3 4 5 6 Tetrafluorophthalonitrile
Fluoride Fluoropolymers Hydrofluoric Acid/Foaming Agent Fluoride Salt Fluorine-Containing

3,4,5,6-Tetrafluorophthalonitrile

Duxiu Chemical

Specifications

HS Code

961932

Chemical Formula C6F4N2
Molecular Weight 188.07
Appearance white to off - white solid
Melting Point 76 - 79 °C
Boiling Point 186 - 188 °C
Density 1.63 g/cm³
Solubility Soluble in some organic solvents like dichloromethane
Vapor Pressure Low vapor pressure at room temperature
Stability Stable under normal conditions
Hazard May cause skin, eye and respiratory irritation

As an accredited 3,4,5,6-Tetrafluorophthalonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 3,4,5,6 - Tetrafluorophthalonitrile packaged in a sealed, chemical - resistant bottle.
Storage Store 3,4,5,6 - Tetrafluorophthalonitrile in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances like strong oxidizers. Store in a tightly sealed container to prevent moisture absorption and potential degradation, ensuring its stability during storage.
Shipping 3,4,5,6 - Tetrafluorophthalonitrile is shipped in sealed, corrosion - resistant containers. Adequate cushioning is used to prevent breakage. Shipments follow strict hazardous chemical transport regulations for safe transit.
Free Quote

Competitive 3,4,5,6-Tetrafluorophthalonitrile prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@bouling-chem.com.

We will respond to you as soon as possible.

Tel: +8615371019725

Email: sales7@bouling-chem.com

3,4,5,6-Tetrafluorophthalonitrile
General Information
Historical Development
"Notes on the Evolution of 3,4,5,6-tetrafluoro-terephthalonitrile"
3,4,5,6-tetrafluoro-terephthalonitrile is also a chemical thing. Its initial appearance depends on the research of chemistry. In the past, everyone was dedicated to the decomposition and synthesis of substances. After years of research, this compound was obtained.
At the beginning, the synthesis method was quite difficult, and the selection of raw materials and the control of reactions were all difficult problems. However, the craftsmen did not stop, with perseverance, to study the mechanism. Gradually, the process improved, and the yield also increased.
As the years passed, the use of this compound became more and more widespread. Emerging in various fields, it contributed to the development of chemistry and the rise of industry. From the perspective of it, it has relied on the diligence of all scholars from the beginning to prosperity, and has finally become the grand view of today.
Product Overview
3,4,5,6-tetrafluoro-terephthalonitrile, Product Overview
3,4,5,6-tetrafluoro-terephthalonitrile is a key raw material for organic synthesis. It forms a white crystalline powder with high purity and good chemical stability.
This product is widely used in the fields of medicine, pesticides and electronic materials. In medicine, it helps to create new special drugs and improve therapeutic efficacy; in pesticides, it can produce high-efficiency and low-toxicity pesticides to protect crop growth; in electronic materials, it is an important substrate for the manufacture of high-end electronic components. With its stability characteristics, it guarantees excellent component performance.
Production of this product adopts advanced technology, and each step is precisely controlled to ensure high quality. The products have been strictly tested, and all indicators meet high standards, which can meet the needs of all walks of life. Stable supply, proper packaging, easy transportation and storage. Sincerely a high-quality choice for cooperation between all parties.
Physical & Chemical Properties
On the physical state and properties of 3,4,5,6-tetrafluoro-terephthalonitrile
3,4,5,6-tetrafluoro-terephthalonitrile, which is a substance and has specific physical and chemical properties. Looking at its shape, at room temperature, or in a crystalline state, pure and color, like frost and snow. Its melting point is very different, and accurate measurement shows that it begins to melt at a specific temperature. This temperature is its inherent nature and is related to the attractive force and arrangement between molecules.
On the chemical properties, the nitrile group is active and can participate in many reactions. Under suitable conditions, it can combine with other substances to derive new substances. The fluorine atom also has characteristics and strong electronegativity, which makes the molecule have unique chemical activity. In the field of organic synthesis, it is often used as a key raw material to help form a variety of compounds, or for the creation of new drugs, or for the development of high-tech materials. It has a wide range of uses and promising prospects. It is indeed an important part of chemical research and industrial production.
Technical Specifications & Labeling
3,4,5,6-Tetrafluoro-terephthalonitrile Technical Specifications and Labeling
There is now 3,4,5,6-Tetrafluoro-terephthalonitrile, and its technical specifications are related to many important items. In terms of ingredients, it needs to be pure and free of impurities, and the proportion of impurities contained must meet specific regulations. The appearance should be [specific appearance description], with uniform color and no visible defects.
Its labeling is also very critical. On the packaging, the name of this product must be stated, that is, "3,4,5,6-Tetrafluoro-terephthalonitrile", and the exact content value must be marked. At the same time, the relevant physical properties, such as melting point, boiling point, and other parameters, should also be clearly identified, so that the user can know their characteristics and use them correctly to ensure that the product is in the market circulation and application, and there are rules to follow, each according to its type, and each suitable for its own use.
Preparation Method
3,4,5,6-Tetrafluorophthalonitrile is a delicate molecule with tetrafluorosubstituted benzene ring and dinitrile functional group. The preparation method is not easy and needs to be strictly implemented.

First, raw material selection

Use tetrafluorobenzene as the base material, assisted by cyaniding reagent and suitable catalyst. The raw material must be pure, free of water and impurities, in order to obtain high-purity products.

Second, preliminary cyanidation

In an organic solvent (such as dimethylformamide), add hydrogen cyanide or sodium cyanide to tetrafluorobenzene, and with the help of catalysts (such as copper powder, copper salt), promote the fixed-point replacement of nitrile based on the ortho position of the benzene ring.

Third, reaction conditions

The heating temperature should be controlled at 120 to 160 degrees Celsius, and the reaction time ranges from several hours to dozens of hours. However, it is necessary to stir evenly to ensure the complete reaction.

Fourth, post-treatment

After the reaction is completed, cool and filter to remove solid impurities. Wash with water to remove residual inorganic salts, and then recrystallize and purify with organic solvents.

Fifth, purification process

Recrystallization uses mixed solvents such as ethanol and acetone, and repeated crystallization ensures a purity of more than 99%. Column chromatography can also be used to assist purification.

Sixth, safety and environmental protection

Cyanide is highly toxic in the reaction, and leakage is strictly prohibited during operation. Waste liquid must be specially treated and must not be discharged at will. Protecting nature is the virtue of modern craftsmen.
Chemical Reactions & Modifications
There is now a thing, named 3,4,5,6 - Tetrafluorophthalonitrile. On the way of transformation, scholars have studied its application and nature.
Those who adapt to it, or encounter other qualities, change by touch. If you add various agents, or change it with temperature or pressure, its molecular structure is easy, and it becomes a new quality. This is a sign of adaptation.
As for goodness, if you want to make this material excellent, it is widely used. Or change its structure, increase its stability, or make it easy to control, and reduce energy consumption. Through various methods, I hope that it can develop its growth in work and research, and benefit everyone. This is the pursuit of goodness.
The study of the transformation of this thing should be related to goodness. If you can understand its principles and be good at its laws, you will transform the Tao, add new colors, and use it for future generations, which will be of infinite benefit.
Synonyms & Product Names
Now there is a thing called 3, 4, 5, 6 - Tetrafluorophthalonitrile. It also has other names, which cover all things in the world, and the names are not the same, or because of differences in regions, or because of different uses.
These 3, 4, 5, 6 - Tetrafluorophthalonitrile, among merchants, and also have the names of commodities. People trade and call the names of their commodities to indicate the things they refer to. And from its meaning, it is also called synonymous. The name of the synonym is designed to accurately indicate the meaning, so that the person who hears it knows the characteristics of the thing.
The name of the thing, the name of the synonym and the name of the commodity are all signs of recognizing things. Although the names are different, they refer to one. Just as the ancients said: "Although the names are different, they are all in one place." The synonymous names and trade names of 3,4,5,6-Tetrafluorophthalonitrile are widely spread in the industry and are well known to everyone. They help the industry operate smoothly and communicate with each other.
Safety & Operational Standards
Specifications for the safety and operation of 3,4,5,6-tetrafluoro-terephthalonitrile
If you want to do a good job, you must first sharpen your tools; if you want to ensure the safety of production, you must understand the rules of operation. In today's discussion of 3,4,5,6-tetrafluoro-terephthalonitrile, its safety and operation standards are of paramount importance, and those who work must not ignore it.
When storing, it is advisable to choose a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent accidents. This material should be stored in separate stores with oxidants, acids, bases, etc., and must not be mixed to avoid chemical reactions and danger. The storage temperature should not exceed 30 ° C, and the relative humidity should be controlled below 80%, so that the storage can be stable.
When operating, it is necessary to strictly follow the norms. Operators must be professionally trained and familiar with the essentials of operation before they can act. The operation room should be equipped with good ventilation and ventilation devices to expel harmful gases. When operating, wear protective clothing, protective gloves and goggles, and be fully armed to protect your own safety. If you accidentally touch the skin, rinse with a large amount of flowing water immediately; if it enters the eyes, lift the eyelids immediately, rinse with flowing water or normal saline, and seek medical treatment as soon as possible.
When handling, it should be handled lightly, and do not drop or pressure it to avoid damage to the package and leakage. In the event of a leak, emergency personnel should arrive at the scene as soon as possible, wearing self-contained positive pressure breathing apparatus and anti-virus clothing. Isolate the leaking contaminated area first, and restrict personnel from entering and leaving. Small leaks can be collected in a dry, clean, covered container with a clean shovel; large leaks need to be built or dug for containment, covered with foam to reduce vapor disasters, and then disposed of in accordance with relevant regulations.
In short, in the production, storage, and use of 3,4,5,6-tetrafluoroterephthalonitrile, safety and operating practices should be adhered to, so as to ensure the safety of personnel, the smooth production, and the risk of disasters.
Application Area
"3, 4, 5, 6 - Tetrafluorophthalonitrile application field"
There is a product named 3, 4, 5, 6 - Tetrafluorophthalonitrile. It is widely used in the field of electronics and can be a key material for the manufacture of high-end chips, which can help improve the performance of chips and make calculations more agile. In material science, it can modify polymers to make them have optimization and mechanical properties, such as enhanced heat resistance and corrosion resistance. In pharmaceutical research and development, or as an intermediary for the synthesis of special drugs, to help overcome difficult diseases. Furthermore, in aerospace, the materials processed by it can reduce weight and enhance the degree, ensuring the safe and efficient operation of aircraft. All of these demonstrate the importance of this object in various fields, and its wide range of uses is indispensable to the development of today's science and technology.
Research & Development
Today there is a thing, name 3, 4, 5, 6 - Tetrafluorophthalonitrile. Our generation focused on this in the way of research and development. Its unique nature, wide range of uses, and potential in various fields.
The process of research, scrutinizing its structure, knowing its physical and chemical properties. The method of fine research and preparation strives for high efficiency and purity. Or improve the old system, or innovate the way, hoping to optimize the output and reduce its cost.
As for the expansion of expansion, think about the expansion of its application. In the electronics and materials industries, it can be used. Looking forward to a new path, develop its growth, and contribute to the prosperity of the industry. Through the unremitting efforts of our generation, we will surely achieve success in the exploration and expansion of this object, which will benefit the world.
Toxicity Research
Study on the toxicity of 3,4,5,6-tetrafluoro-terephthalonitrile
In recent times, various new substances have appeared frequently, and 3,4,5,6-tetrafluoro-terephthalonitrile is also one of them. This substance is gradually used in various industries, but the study of its toxicity is related to everyone's health and cannot be ignored.
According to ancient books, such chemical substances may enter the body through the mouth, nose and skin. At first, it may cause itching and redness of the skin, followed by damage to the respiratory system, causing shortness of breath and cough. And it also has potential harm to the viscera, or it may tire the liver and kidneys, causing it to work.
Today's researchers should collect a wide range of data, scrutinize its toxicological changes, and clarify its harm to life. Those who use this product should also be cautious and take protective measures to avoid it, protect their health, and promote their health.
Future Prospects
In the future, 3, 4, 5, 6 - Tetrafluorophthalonitrile this thing, its development can be looked forward to. This product is unique and unique, and it will be able to reveal the angle in many domains. In the process of construction, it may be possible to transform the complexity to improve the efficiency; scientific and technological research, or to create new materials, to introduce new ones. In the future, its use will be more extensive, like the stars scattered, and it will inject new vitality into the environment. The unlimited development will make the world more colorful, and the prospect will be bright.
Where to Buy 3,4,5,6-Tetrafluorophthalonitrile in China?
As a trusted 3,4,5,6-Tetrafluorophthalonitrile manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3,4,5,6-Tetrafluorophthalonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 3,4,5,6-tetrafluorophthalonitrile
3,4,5,6-tetrafluoro-dimethyl terephthalate, which is a white crystalline powder. Its melting point is quite high, about 145-148 ° C. With this characteristic, it can change the state of matter in a specific temperature environment. Its chemical properties are relatively stable, and its solubility is limited in many common organic solvents, such as methanol, ethanol, acetone, etc. However, in strong polar organic solvents, such as dimethyl sulfoxide (DMSO) and N, N-dimethylformamide (DMF), it can exhibit some solubility. This compound has two key functional groups of ester groups and fluorine atoms. The ester group gives it the possibility of hydrolysis. Under the catalysis of acid or base, the ester group can react with water to form corresponding acids and alcohols. The introduction of fluorine atoms greatly enhances the stability and hydrophobicity of the molecule. Due to its high C-F bond energy, the chemical stability of the compound is improved and it can resist the erosion of many chemical reagents. At the same time, the enhanced hydrophobicity makes it show unique application value in some fields involving oil-water separation or surface property regulation. In the field of organic synthesis, dimethyl 3,4,5,6-tetrafluoro-terephthalate, as an important intermediate, can be converted into various fluorine-containing organic compounds through a series of chemical reactions, such as transesterification, hydrolysis, acylation, etc., laying the foundation for the synthesis of new fluorine-containing materials and drugs.
What are the physical properties of 3,4,5,6-tetrafluorophthalonitrile
3,4,5,6-Tetrafluoro-dimethyl terephthalate is an organic compound. Its physical properties are quite critical, so let me talk about them one by one. This compound is usually in the state of a white crystalline powder with a fine texture. Its melting point is in a specific range, generally between about 130-134 ° C. At this temperature, it will transform from a solid state to a liquid state. This property is of great significance in many chemical processes, such as purification and molding. When it comes to solubility, it exhibits different behaviors in common organic solvents. In halogenated hydrocarbon solvents such as dichloromethane and chloroform, it has a certain solubility and can be well dispersed to form a uniform solution; in water with strong polarity, the solubility is extremely low and almost insoluble, which is caused by the non-polar characteristics of its molecular structure. This difference in solubility can be used as an important basis in chemical processes such as separation and extraction. Its density is also one of the important physical properties, about 1.55 g/cm ³. This value reflects its mass per unit volume, which needs to be taken into account when involving material storage, transportation and related chemical reaction measurement. In addition, the chemical properties of this compound are relatively stable at room temperature and pressure, and chemical reactions may occur under specific conditions, such as high temperature, strong acid and alkali environment, etc. This requires that during storage and use, appropriate conditions should be selected according to its physical properties to prevent its properties from changing and ensure its quality and performance.
What are the main uses of 3,4,5,6-tetrafluorophthalonitrile?
3,4,5,6-tetrafluoro-dimethyl terephthalate has three main uses. First, in the field of organic synthesis, it is a key monomer for the preparation of special polyester materials. Based on it, it can be polymerized into a polyester with unique properties. This polyester has excellent chemical stability due to fluorine atoms and can resist the erosion of many chemical substances. In the chemical industry, electronics and other industries that require strict material tolerance, it can be used as anti-corrosion coatings, electronic components packaging materials, etc. If this polyester coating is applied to the surface of chemical equipment, it can resist the corrosion of strong acids and alkalis for a long time and prolong the service life of the equipment. Second, in pharmaceutical chemistry, it is often an important intermediate for the synthesis of specific drugs. Due to its special molecular structure, it can introduce specific functional groups to help build biologically active drug molecular structures. For example, by combining it with nitrogen-containing heterocyclic compounds through specific reactions, new drugs with antibacterial and anti-tumor activities can be synthesized, opening up new paths for pharmaceutical research and development. Third, it is also of great value in the field of photoelectricity at the forefront of materials science. It can be used to prepare organic electroluminescent materials (OLEDs). The OLED materials synthesized by it can optimize the luminous performance, improve the luminous efficiency and color purity. In this way, in the manufacture of display screens, the display screen can be clearer and the colors are more gorgeous, promoting the development of display technology.
What are the synthesis methods of 3,4,5,6-tetrafluorophthalonitrile
There are many methods for the synthesis of ethyl 3,4,5,6-tetrafluorobenzoyl acetate. One method can also be started from 3,4,5,6-tetrafluorobenzoic acid. First, the 3,4,5,6-tetrafluorobenzoic acid is co-heated with thionyl chloride to obtain 3,4,5,6-tetrafluorobenzoyl chloride. This step needs to be carried out at a suitable temperature and reaction time, and the sealing of the device should be paid attention to to prevent gas escape. The reaction formula is as follows: 3,4,5,6-tetrafluorobenzoic acid + thionyl chloride → 3,4,5,6-tetrafluorobenzoyl chloride + sulfur dioxide + hydrogen chloride. Then, the prepared 3,4,5,6-tetrafluorobenzoyl chloride is reacted with ethyl acetoacetate under the catalysis of a base. Sodium carbonate and the like can be selected for the base. During the reaction, temperature control and stirring are required to make the reaction sufficient. After the reaction is completed, 3,4,5,6-tetrafluorobenzoyl acetate can be obtained by separation and purification methods, such as extraction and distillation. The reaction also has the formula: 3,4,5,6-tetrafluorobenzoyl chloride + ethyl acetoacetate + base → 3,4,5,6-tetrafluorobenzoyl acetate + base salts. There is another method, which can be obtained from 3,4,5,6-tetrafluorobenzaldehyde. Knoevenagel condensation reaction between shilling 3,4,5,6-tetrafluorobenzaldehyde and diethyl malonate is carried out under the catalysis of organic bases. The reaction environment of this organic base such as pyridine needs to be anhydrous, and the temperature needs to be carefully controlled. After the reaction, an intermediate is obtained, and then the intermediate is hydrolyzed and decarboxylated, and the final result is 3,4,5,6-tetrafluorobenzoyl acetate. The series of reaction steps is complicated, but each step has key operation points, such as controlling the degree of hydrolysis and controlling the conditions of decarboxylation. These two methods have their own advantages and disadvantages. In the actual synthesis, the selection should be considered according to the availability of raw materials, cost, yield and other factors.
What should be paid attention to when storing and transporting 3,4,5,6-tetrafluorophthalonitrile?
3,4,5,6-fluorophthalonitrile has a pure shape and a hot temper. It is easy to change when exposed to wind and sun. It should be stored in a cool and dry room, away from light and moisture, and sealed to prevent wind and frost erosion. The container should be a solid and sealed container to prevent gas leakage and foreign matter invasion. During transportation, it should be placed in a stable and firm container, and should not be carried together with acid, alkali, grease and sundries to prevent chemical reactions. The route should be flat and stable, avoiding violent shocks and exposure to the sun. Avoid splashing when encountering water, and stay away from fire to prevent accidents. If stored for a long time, the container should be checked frequently to prevent leakage and moisture. If there is any abnormality, it should be handled quickly. All these storage and transportation methods must be safe and rigorous to ensure that its quality is not destroyed and its efficacy is preserved.