1 2 4 Trifluorobenzene
Fluoride Fluoropolymers Hydrofluoric Acid/Foaming Agent Fluoride Salt Fluorine-Containing

1,2,4-Trifluorobenzene

Duxiu Chemical

Specifications

HS Code

378638

Chemical Formula C6H3F3
Molar Mass 132.08 g/mol
Appearance Colorless liquid
Odor Characteristic aromatic odor
Density 1.255 g/cm³ at 20 °C
Boiling Point 102 - 104 °C
Melting Point -77 °C
Solubility In Water Insoluble
Vapor Pressure 10 mmHg at 21.4 °C
Flash Point 11 °C
Refractive Index 1.412 at 20 °C

As an accredited 1,2,4-Trifluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,2,4 - Trifluorobenzene in 500 - mL glass bottles, well - sealed for protection.
Storage 1,2,4 - Trifluorobenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly closed container, preferably made of materials resistant to its corrosive nature. Store it separately from oxidizing agents and incompatible substances to prevent dangerous reactions. Ensure proper labeling for easy identification and safety.
Shipping 1,2,4 - Trifluorobenzene, a chemical, is shipped in accordance with strict hazardous material regulations. It's packaged securely in appropriate containers to prevent leakage during transit to ensure safety.
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1,2,4-Trifluorobenzene
General Information
Historical Development
"Historical Development of 1,2,4-Trifluorobenzene"
The rise of 1,2,4-trifluorobenzene began when the chemical technology was gradually refined. At the beginning, people dedicated themselves to studying in the field of organic synthesis, wanting to obtain this special compound to meet the needs of many industries.
In the past, scholars have devoted themselves to exploring the method of its preparation. After several attempts, either improving the old method or creating a new method. At the beginning, the preparation was difficult and the yield was quite low, but everyone was not discouraged.
With the passage of time, science and technology have advanced, and the preparation process has become more complete. Its use in medicine, materials and other industries has gradually expanded, contributing to the development of many fields and becoming an indispensable part of the chemical industry. This is also the outline of its historical development.
Product Overview
1,2,4-Trifluorobenzene, product profile
1,2,4-trifluorobenzene, is one of the most important raw materials in the chemical industry. Its color is transparent, it has a special taste, and it has good solubility.
This product is very good in the field of synthetic technology. It can be used as a key factor in the synthesis of multi-effect compounds, assisting chemical research and development, such as antibacterial and antiviral new technologies. It is also an important product in the manufacturing industry, which can increase the efficiency of waste and weeding, and has high efficiency and low toxicity.
Its physical rationality is fixed, and the boiling and melting have specific values, which provide convenience for the use of different processes. However, its chemical activity cannot be ignored. A specific meeting can lead to subtle reactions and achieve new compounds. On the way forward in the chemical industry, 1,2,4-trifluorobenzene has its unique characteristics, and it is necessary to develop its talents in more fields.
Physical & Chemical Properties
"On the Physical Properties of 1,2,4-Trifluorobenzene"
On 1,2,4-trifluorobenzene, an organic compound with unique physical and chemical properties. Looking at its physical properties, at room temperature and pressure, 1,2,4-trifluorobenzene is a colorless and transparent liquid with a special odor. Its boiling point is about 102-104 ° C, and the melting point is about -35 ° C. This boiling point characteristic makes the substance in a clear state in a specific temperature range. The density is about 1.435g/cm ³, and it is miscible with common organic solvents, such as ethanol, ether, etc., showing good solubility.
In addition to chemical properties, the presence of fluorine atoms in 1,2,4-trifluorobenzene changes the electron cloud density of the benzene ring, resulting in different chemical activities. Electrophilic substitution reactions can occur. Due to the electron-absorbing effect of fluorine atoms, the reaction check point is slightly different from that of ordinary benzene derivatives. This compound is widely used in the field of organic synthesis, and can be used as an intermediate to participate in the construction of many complex organic molecules. With its physical and chemical properties, it is possible to synthesize new substances.
Technical Specifications & Labeling
Technical specifications and labels of 1,2,4-trifluorobenzene (commodity parameters)
1,2,4-trifluorobenzene is an important chemical product. Its technical specifications are related to purity, which must reach extremely high standards, and the impurity content must be strictly controlled. In the preparation process, each step is precisely handled to ensure the stability of product quality.
View its logo, and the product parameters are detailed. Indicate the chemical structure, clearly show the molecular composition; list the physical properties, such as boiling point, melting point, density, etc., so that the user can understand its characteristics. And on the packaging label, warn the relevant precautions, related to toxicity, explosion risk, etc., so that the contact should be cautious. In this way, this product can be used safely and effectively in industrial applications, scientific research, and other fields.
Preparation Method
"The method of 1,2,4-trifluorobenzene (raw material production, reverse step, catalytic production) "
For 1,2,4-trifluorobenzene, the first suitable raw material is required. Often start with fluorine-containing compounds, such as a fluorine-substituted aromatic. Its production process starts with a specific reaction. The raw material is placed in the appropriate reaction kettle, control, etc. The first step is to make the raw material A catalytic connection, the catalytic reaction can be made of gold, and the reaction can replace the reaction, so that the fluorine atom is introduced into the aromatic layer one by one.
Then, the reaction parts are integrated, the degree of change is changed, and the help is added to promote the generation of 1,2,4-trifluorobenzene in the reverse direction. In the reverse step, the reverse step is controlled, and the reverse step is reversed in each step, and the refined extract is required to remove the chemical.
Catalytic extraction is very important in the whole process. Catalytic catalysis can reduce the reverse activation energy and accelerate the reverse rate. The active center of the raw material molecules interact, leading to the rearrangement of the atomic clouds, and the substitution of fluorine atoms. In this way, the series of steps can obtain 1,2,4-trifluorobenzene with a high temperature.
Chemical Reactions & Modifications
On the chemical reaction and modification of 1,2,4-trifluorobenzene
The wonders of chemistry and the changes are endless. In today's talk, 1,2,4-trifluorobenzene has unique properties and shows special ability in various chemical reactions.
1,2,4-trifluorobenzene, containing fluorine atoms, fluorine, has strong electronegativity, resulting in quite different chemical activities. In the nucleophilic substitution reaction, fluorine atoms can be used as leaving groups, because the negative ions formed after leaving are stable. This property enables 1,2,4-trifluorobenzene to react with many nucleophiles to form novel compounds.
However, its reaction is also limited, such as the reaction conditions need to be precisely controlled, otherwise it will be difficult to achieve expectations. In order to optimize, 1, 2, 4-trifluorobenzene can be modified. The introduction of specific functional groups can adjust its electron cloud density, improve its reactivity and selectivity. In this way, high yield products may be obtained under milder conditions, broadening its application in the field of organic synthesis.
Synonyms & Product Names
Synonyms of 1,2,4-trifluorobenzene and trade name
There is a thing named 1,2,4-trifluorobenzene. This thing is in the market, and there are also various synonyms and trade names.
Its synonyms refer to the same substance in different expressions. Or according to its chemical properties, or according to its structural characteristics, it is called by others.
As for the trade name, the merchants take a unique name to sell it in order to recognize its characteristics. This 1,2,4-trifluorobenzene is useful in various industries, and each merchant takes different trade names to make it stand out.
Although the names are different, they all refer to this 1,2,4-trifluorobenzene. Its synonyms and trade names are designed to facilitate the recognition and trading of this substance in the industry.
Safety & Operational Standards
Safety and Operation Specifications for 1,2,4-Trifluorobenzene
1,2,4-Trifluorobenzene is a chemical substance. It is related to safety and operation specifications, and it is essential to be detailed.
#1. Storage Regulations
1,2,4-Trifluorobenzene should be stored in a cool and ventilated warehouse. Keep away from fire and heat sources, and the storage temperature should not exceed 37 ° C. It should be stored separately from oxidants and edible chemicals, and should not be mixed. The storage area should be equipped with leakage emergency treatment equipment and suitable containment materials to prevent accidents.
#2. Standard of operation
When operating, it is necessary to strictly seal and strengthen ventilation. Operators should be specially trained and strictly follow the operating procedures. It is recommended that operators wear anti-virus clothing and rubber oil-resistant gloves to prevent contact with objects. Keep away from fires and heat sources, and smoke is strictly prohibited in the workplace. Use explosion-proof ventilation systems and equipment. Prevent vapor leakage into the air. Avoid contact with oxidants. Filling should control the flow rate and have a grounding device to prevent static electricity accumulation. When handling, it should be light and unloaded to prevent damage to packaging and containers.
#3. Emergency measures
If there is a leak, quickly evacuate the personnel in the leaked contaminated area to the safe area, and isolate them to strictly restrict access. Cut off the source of fire. It is recommended that emergency personnel wear self-contained positive pressure breathing apparatus and anti-toxic clothing. Cut off the source of leakage as much as possible. Prevent it from flowing into restricted spaces such as sewers and flood drains. Small leaks: adsorb or absorb with sand or other non-combustible materials. It can also be scrubbed with an emulsion made of non-combustible dispersants, and the lotion is diluted and placed into the wastewater system. Large leaks: build a embankment or dig a pit for containment. Cover with foam to reduce vapor disasters. Transfer to a tanker or a special collector with an explosion-proof pump, and recycle or transport it to a waste treatment site for disposal.
#4. Methods of protection
Respiratory system protection: Wear a self-priming filter gas mask (half mask) when you may come into contact with its vapors. During emergency rescue or evacuation, you should wear an air respirator. Eye protection: Wear chemical safety glasses. Body protection: Wear anti-poison infiltration work clothes. Hand protection: Wear rubber oil-resistant gloves. Other protection: No smoking, eating and drinking at the work site. After work, shower and change clothes. Pay attention to personal hygiene.
The safety and operation specifications of 1,2,4-trifluorobenzene are related to personal safety and the environment. It cannot be slack. It must be strictly practiced.
Application Area
The use of 1,2,4-trifluorobenzene
Now there is a thing called 1,2,4-trifluorobenzene, and its use is wide. In the field of medicine, it can be an essential material for making good medicines. With its unique characteristics, it helps the medicine to achieve its effect, treats all kinds of diseases, and relieves people's pain.
In the world of agrochemical, it also has its function. It can participate in the system of pesticides, protect the crops in the field, control diseases and pests, and ensure the hope of a bumper harvest.
And in the way of materials, it can be the foundation of new materials. Make the material have special qualities, suitable for all needs, used in high-tech tools, and promote the progress of science and technology.
From this perspective, 1,2,4-trifluorobenzene is used in medicine, agrochemistry, and materials, all of which are related to people's livelihood and benefit the country and the state. Its power cannot be underestimated.
Research & Development
"On Research and Development"
Today there is a thing named 1,2,4-trifluorobenzene, which has unique properties and is the key to all kinds of research. On the way of research, all the wise men exhausted their wisdom, wanting to understand its quality and its use.
At the beginning, they only knew its shape, but not its mystery. However, the crowd worked tirelessly, studying over the years, and gradually peeking at the door. Observing its chemical properties can be used in a special way, or as the basis of medicine, or as the beginning of material.
As for development, everyone is united and seeks its wide use. In the field of industry, seek its purity and increase its production; in the forest of academia, explore its new energy, and hope to expand the New Territories. Although the road is bumpy, those who are determined are fearless and determined to move forward. I hope this 1,2,4-trifluorobenzene can shine brightly in the research and development, and benefit everyone.
Toxicity Research
Study on the toxicity of 1,2,4-trifluorobenzene
In recent years, there are things called 1,2,4-trifluorobenzene, which has become more and more popular in various industries. However, the study of its toxicity is related to the health of the people and the peace of the world, which must not be ignored.
Examine the classics in detail, and today's researchers explore its properties and apply various experiments. Take insects and animals as a test, and observe the symptoms of 1,2,4-trifluorobenzene. Or see its body shape is inconsistent, its behavior is abnormal, and even the organs are damaged.
And also, it is scattered in the ring, through water, gas and all things. Plants sense it, or it may cause poor vitality; if a person touches it, the light ones will be uncomfortable, and the serious ones will be plagued by illness. Therefore, if you want to make this business, you should be cautious and study its prevention methods to ensure the well-being of the people, maintain the tranquility of the surrounding universe, and do not let the harm of toxicity go unchecked.
Future Prospects
"Future Prospects"
Today there is a thing called "1, 2, 4 - Trifluorobenzene", which is a chemical product. Its future prospects are almost too many. With the development of science and technology, this thing may have a new appearance in the field of materials. It can be the foundation of high-tech materials, and help its performance, quality and efficiency can be improved.
And in the process of research and development, it may also play an important role. Or it may form a new way to help the improvement of products, and the health and well-being of the world. Its work is also expected to be improved, improve efficiency and reduce consumption, and conform to today's development. In the future, "1, 2, 4 - Trifluorobenzene" will definitely be able to make a big impact, and it will be a new chapter in many fields.
Where to Buy 1,2,4-Trifluorobenzene in China?
As a trusted 1,2,4-Trifluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2,4-Trifluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2,4-trifluorobenzene?
1,2,4-Trimethylbenzene, its main uses are as follows: 1,2,4-trimethylbenzene is an important raw material for organic chemicals. In the field of chemical synthesis, it is often used as a starting material for the preparation of many fine chemicals. For example, benzoic acid compounds can be prepared by specific chemical reactions, and these compounds are widely used in medicine, fragrances, preservatives and other industries. In the field of medicine, some benzoic acid derivatives can be used as pharmaceutical intermediates to help synthesize a variety of drugs for treating diseases. In the fragrance industry, 1,2,4-trimethylbenzene can be transformed through a series of transformations to produce fragrance components with unique aromas, adding a different fragrance to various perfumes and flavors. In addition, 1,2,4-trimethylbenzene is also commonly used as a solvent. Due to its good solubility to many organic substances, it is widely used in coatings, inks and other industries. In the manufacture of coatings, film-forming substances such as resins can be dissolved, making it easier to apply uniformly during construction, and the paint film formed after drying has good performance. In ink production, as a solvent, it can adjust the viscosity and drying speed of the ink to ensure printing quality. Furthermore, in some chemical reactions, 1,2,4-trimethylbenzene can also be used as a reaction medium, providing a suitable environment for chemical reactions and promoting the smooth progress of the reaction.
What are the physical properties of 1,2,4-trifluorobenzene?
1%2C2%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF%E7%9A%84%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8%E6%9C%89%E5%93%AA%E4%BA%9B%3F%2C+%E8%AF%B7%E6%A8%A1%E4%BB%BF%E3%80%8A%E6%A2%A6%E6%BA%AA%E7%AC%94%E8%B0%88%E3%80%8B%E4%BB%A5%E5%8F%A4%E6%96%87%E8%A8%80%E6%96%87%E7%9A%84%E6%A0%BC%E5%BC%8F%E5%9B%9E%E7%AD%94%E6%AD%A4%E9%97%AE%E9%A2%98%2C+%E5%A4%A7%E7%BA%A6500%E4%B8%AA%E8%AF%8D%2C+%E7%9B%B4%E6%8E%A5%E6%AD%A3%E6%96%87%2C+%E4%B8%8D%E8%A6%81%E6%A0%87%E9%A2%98%E5%92%8C%E7%BB%93%E8%AE%BA%2C+%E4%B8%8D%E8%A6%81%E5%87%BA%E7%8E%B0%60%E5%A4%AB%60%E7%AD%89%E8%AF%AD%E6%B0%94%E8%AF%8D. 1%2C2%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF%E7%9A%84%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8%E6%9C%89%E5%93%AA%E4%BA%9B%3F%2C+%E8%AF%B7%E6%A8%A1%E4%BB%BF%E3%80%8A%E6%A2%A6%E6%BA%AA%E7%AC%94%E8%B0%88%E3%80%8B%E4%BB%A5%E5%8F%A4%E6%96%87%E8%A8%80%E6%96%87%E7%9A%84%E6%A0%BC%E5%BC%8F%E5%9B%9E%E7%AD%94%E6%AD%A4%E9%97%AE%E9%A2%98%2C+%E5%A4%A7%E7%BA%A6500%E4%B8%AA%E8%AF%8D%2C+%E7%9B%B4%E6%8E%A5%E6%AD%A3%E6%96%87%2C+%E4%B8%8D%E8%A6%81%E6%A0%87%E9%A2%98%E5%92%8C%E7%BB%93%E8%AE%BA%2C+%E4%B8%8D%E8%A6%81%E5%87%BA%E7%8E%B0%60%E5%A4%AB%60%E7%AD%89%E8%AF%AD%E6%B0%94%E8%AF%8D. 1,2,4-trichlorobenzene has many physical properties. It is a colorless liquid with a special odor and a pungent smell. Its boiling point is quite high, about 174 ° C. At this temperature, the liquid will rise into a gaseous state. The melting point is also not low, reaching 53 ° C. When the temperature drops to this temperature, the liquid will condense into a solid state. This substance has a higher density than water. If placed in water, it will sink to the bottom of the water. It is slightly soluble in water and difficult to disperse uniformly in water. However, it can be soluble in organic solvents such as ethanol and ether, and it can be better mutually soluble. Its vapor pressure is low at room temperature, which means that it evaporates relatively slowly. However, although the evaporation is slow, its vapor is still toxic and may be harmful to health if inhaled into the human body. The physical properties of 1,2,4-trichlorobenzene are of great significance in the chemical industry and other fields. Because of its boiling point, solubility and other properties, it is often used in organic synthesis solvents, as well as in the preparation of pesticides, medicines and other products. Understanding its physical properties is of key value in rational use and proper protection.
Is the chemical properties of 1,2,4-trifluorobenzene stable?
The chemical properties of 1,2,4-trichlorobenzene are quite stable. In this compound, the chlorine atom is connected to the benzene ring, and the benzene ring has a conjugated system, which makes the structure stable. The electronegativity of the chlorine atom is relatively large, although it has an impact on the electron cloud distribution of the benzene ring, it is difficult to change the overall stability of the benzene ring. Under normal conditions, 1,2,4-trichlorobenzene is not prone to hydrolysis, oxidation and other reactions. At room temperature and pressure, it can be stored for a long time without significant change. In case of high temperature, catalyst or specific strong reaction conditions, it can also participate in some chemical reactions. For example, in the presence of a specific catalyst, or a nucleophilic substitution reaction can occur, and the chlorine atom But in general, in the common environment, the conjugated structure of the 1,2,4-trichlorobenzene ring and the properties of the chlorine atom show a stable chemical property.
What are the production methods of 1,2,4-trifluorobenzene?
1%2C2%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF%E7%9A%84%E7%94%9F%E4%BA%A7%E6%96%B9%E6%B3%95%E6%9C%89%E5%A4%9A%E7%A7%8D%E3%80%82 First, it can be obtained by sulfonation of o-xylene and alkali melting. First, o-xylene is sulfonated, a sulfonic acid group is introduced, and then the sulfonic acid group is replaced by a hydroxyl group through an alkali fusion reaction, so as to obtain 1%2C2%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF. This process requires specific reaction conditions and operation skills. When sulfonating, attention should be paid to the selection of sulfonating agent and the control of reaction temperature. When alkali is melted, the amount of alkali and the reaction time are also required. Second, meta-trimethylbenzene is used as the raw material and can be obtained by oxidation reaction. Under suitable catalyst and reaction environment, the methyl of meta-trimethylbenzene is oxidized and gradually converted into 1%2C2%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF. In this way, the activity and selectivity of the catalyst have a significant impact on the yield and purity of the product. At the same time, the temperature and Third, it can also be extracted and separated from coal tar. Coal tar has a complex composition and contains many aromatic hydrocarbons. After a series of separation methods such as fractionation, extraction, and rectification, 1%2C2%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF can be separated and purified from the complex components of coal tar. However, this method requires quite high separation equipment and process to ensure effective separation and obtain high-purity products. Different preparation methods have their own advantages and disadvantages. In actual production, many factors such as raw material cost, reaction conditions, product quality and yield should be comprehensively considered, and a suitable production method should be reasonably selected.
What should be paid attention to when storing and transporting 1,2,4-trifluorobenzene?
1%2C2%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF%E5%9C%A8%E5%82%A8%E5%AD%98%E5%92%8C%E8%BF%90%E8%BE%93%E6%97%B6%EF%BC%8C%E5%BF%85%E9%A1%BB%E6%B3%A8%E6%84%8F%E4%B8%8B%E5%88%97%E4%BA%8B%E9%A1%B9%EF%BC%9A First, its material is flammable. When storing and transporting, it must be kept away from fire and heat sources, and avoid direct sunlight to prevent ignition due to high temperature and accidental disasters. Second, this substance is toxic to a certain extent. The storage place and the equipment transported must be tightly sealed to prevent it from evaporating and escaping, harming humans and animals. If it is accidentally touched or sucked during the process, wash it with water as soon as possible and seek medical treatment. Furthermore, the storage place needs to be dry and well ventilated. Humid environment can easily cause it to deteriorate, affecting its quality and performance. If the ventilation is smooth, it can reduce its concentration in the air and reduce the risk of explosion and poisoning. In addition, when shipping, it should be carried with special equipment and vehicles in accordance with relevant regulations. Its packaging must also be sturdy and tight, marked with obvious warning signs, so that everyone knows its risk and handles it with caution. And during the storage and transportation process, a special person needs to be set up to supervise and make inspections to check whether the packaging is damaged or leaked. If there is any abnormality, it should be dealt with quickly to ensure safety.