P-Bromobenzotrifluoride

Duxiu Chemical

Specifications

HS Code	473860
Chemical Formula	C7H4BrF3
Molar Mass	225.005 g/mol
Appearance	Colorless to light yellow liquid
Density	1.635 g/cm³ (at 20 °C)
Boiling Point	196 - 198 °C
Melting Point	−27 °C
Flash Point	78 °C
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, ether
Vapor Pressure	Low vapor pressure
Refractive Index	1.476 (at 20 °C)

As an accredited P-Bromobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	500g of P - Bromobenzotrifluoride packaged in a sealed, corrosion - resistant bottle.
Storage	P - Bromobenzotrifluoride should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames. Keep it in a tightly sealed container to prevent leakage. Store it separately from oxidizing agents and reactive chemicals. Ensure the storage location has proper spill - containment measures in case of an accident.
Shipping	P - Bromobenzotrifluoride is shipped in specialized containers compliant with chemical transport regulations. It's carefully packaged to prevent leakage, transported under controlled conditions to maintain stability during transit.

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General Information

Historical Development

In the past, the research of chemical things has gradually flourished in the world. P - Bromobenzotrifluoride this thing, its beginning, the researcher observes its nature and studies its success, and has gone through a difficult journey. At the beginning, the cognition is still shallow, but the sages are unremitting. Or in the room of seclusion, the candle burning night research, analyze its composition, explore its reaction rules.
Years have passed, and technology has advanced. Researchers use new techniques and new tools to study its characteristics in detail. From ignorance to clarity, from crude to subtle. The unfathomable nature of the past is now obvious. Its application is also gradually widening, and it has its merits in the fields of medicine and materials.
Looking at its historical development, it is known from ignorance, and widely used from rarity. It all depends on the efforts of researchers and the inheritance of successive generations to have today's appearance. This is an example of the evolution of chemical research.

Product Overview

"P Bromobenzotrifluoride Product Overview"
P Bromobenzotrifluoride, is an important product of chemical research. Its unique properties, with the characteristics of aryl halide and fluorine-containing groups. Looking at its shape, it is a colorless to slightly yellow transparent liquid at room temperature, with a specific smell, which can be identified around.
The preparation method depends on the magic of organic synthesis. With a specific halogenation reaction and fluorination method, through exquisite steps, the reactants interact with each other under the help of temperature, pressure and catalyst, and finally obtain this product.
In the field of application, P Bromobenzotrifluoride has a wide range of uses. In the field of medicinal chemistry, it is a key intermediate for the synthesis of a variety of specific drugs. With its structural characteristics, specific functional groups can be introduced to form molecules with unique pharmacological activities. In the field of materials science, it is also an important angle for the preparation of high-performance fluorine-containing materials, helping materials to obtain excellent chemical stability, thermal stability and electrical properties. It is like a cornerstone in chemical synthesis, paving the way for the creation of many complex organic compounds.

Physical & Chemical Properties

Today there is a thing called P-Bromobenzotrifluoride. Its physical and chemical properties are particularly important and cannot be ignored.
Looking at its physical properties, at room temperature, this thing is often in a liquid state, with a clear and transparent color, like jade dew. Its boiling point is quite different from that of ordinary things, and the value is specific, because of the force between molecules. As for the melting point, it also has a certain number, which is restricted by its structure. And its density is moderate, and it has its own unique state in liquids.
On its chemical properties, it contains atoms such as fluorine and bromine, which makes its chemical activity unique. The strong electronegativity of fluorine atoms makes the distribution of molecular electron clouds special, which affects its reactivity. Bromine atoms are also the key to the reaction and can participate in a variety of chemical transformations. The interaction between the two makes P-Bromobenzotrifluoride exhibit unique behaviors in many chemical reactions, providing many possibilities for chemical research and applications.

Technical Specifications & Labeling

"P - Bromobenzotrifluoride Technical Specification and Identification (Product Parameters) "
For P - Bromobenzotrifluoride, it is a chemical product, and its technical specification and identification are the key. As far as technical specifications are concerned, the synthesis method needs to be accurate. The selection of starting materials must be pure, and the proportion must be determined. The temperature and duration of the reaction are strictly controlled. The temperature control is within a certain range, and a certain time must be elapsed to make the reaction sufficient and obtain a high-purity product.
As for the label, the name P - Bromobenzotrifluoride must be stated on the product, and the product parameters must be listed in detail. Such as purity, it should meet a certain standard; physical parameters such as density and boiling point are also indispensable. In this way, users can clarify its characteristics and use it in the correct way to ensure the smooth operation of experiments and production, and avoid the risk of accidents.

Preparation Method

The method of preparing P-Bromobenzotrifluoride, the raw material, bromobenzene and trifluoromethylation reagent is also. First, the bromobenzene is mixed with the reagent, the temperature is controlled at a moderate level, and the catalytic agent is applied to induce the reaction to occur. The first step of the reaction is to replace the bromine on the bromobenzene with the trifluoromethyl group in the reagent, and go through electron transfer, bond fracture and formation.
Preparation process, in a special reactor, the temperature is adjusted by a precise temperature control device, the raw material is pumped at a constant current, and the mixer promotes its full miscibility. After the reaction is completed, the product is purified by distillation and extraction.
Catalytic mechanism, the catalyst activates the carbon-bromine bond of bromobenzene, reduces the reaction energy barrier, and increases the rate of trifluoromethylation. In this way, P-Bromobenzotrifluoride can be efficiently prepared, which is an important way for chemical production.

Chemical Reactions & Modifications

Nowadays, there are many studies on the transformation and modification of this substance in P-Bromobenzotrifluoride. The way of transformation is like the combination of yin and yang, and the interaction between substances produces new changes. The transformation of P-Bromobenzotrifluoride involves nucleophilic substitution, free radical reaction, etc. The method of the past may be cumbersome and inefficient.
Therefore, if you want to modify it, you can hope that the reaction conditions are mild, the rate is faster, and the yield is higher. Such as improving the catalyst, or finding an appropriate solvent to make the intermolecular interaction suitable to promote the smooth flow of the reaction. Or change its structure, add or subtract groups, adjust its electron cloud density, and change its activity and selectivity. These are all the learners of transformation, on the road of P-Bromobenzotrifluoride and modification, they should think deeply about what they do, and hope to obtain exquisite methods to achieve transformation.

Synonyms & Product Names

P Bromobenzotrifluoride is an important compound in organic chemistry. Its synonymous name is also expressed in various academic circles. Or p-bromotrifluorotoluene, this name indicates the relative position of the bromine atom and the trifluoromethyl according to its chemical structure. Also known as 4-bromotrifluorotoluene, this number "4" indicates the position of the bromine atom in the benzene ring.
As for the trade name, there are also different names on the market. Some manufacturers market this product under unique names, but they all refer to it. The variety of synonyms and trade names stems from the development of chemical research and the difference in commercial markets. But its essence, all are P Bromobenzotrifluoride, in the field of organic synthesis, often used as a key intermediate for the preparation of various fine chemicals, its synonymous name and clear trade name, in scientific research and industrial applications are of great significance.

Safety & Operational Standards

"P - Bromobenzotrifluoride Product Safety and Operation Specifications"
P - Bromobenzotrifluoride is an important substance for chemical research. Safety and operation standards are of paramount importance during its experimentation and production.
First words Storage method. When placing this material in a cool, dry and well-ventilated place, away from fire and heat sources. Because it has certain chemical activity, if stored improperly, it is prone to danger. It must be stored separately from oxidizing agents and alkalis, etc., and should not be mixed with storage to prevent chemical reactions and endanger safety.
The rules of operation are discussed. Operators must be specially trained and strictly abide by the operating procedures. When operating, appropriate protective equipment should be worn, such as gas masks, chemical protective clothing, etc., to protect their own safety. The operating environment needs to have good ventilation conditions to prevent gas accumulation. When taking P-Bromobenzotrifluoride, the action should be steady and light to avoid spillage. If there is a spillage, emergency measures should be taken immediately, collected with special adsorption materials, properly handled, and cannot be discarded at will to avoid polluting the environment.
Furthermore, it is related to transportation. During transportation, ensure that the container is well sealed to prevent leakage. Transportation vehicles need to be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. And the driving route should avoid densely populated areas to reduce the risk.
All of these are the standards for the safety and operation of P-Bromobenzotrifluoride products. Following this rule can ensure the smooth operation of experiments and production, and ensure the safety of personnel and the environment from harm.

Application Area

In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize many special drugs to cure various diseases. In materials science, it can participate in the preparation of high-performance materials, so that materials have special chemical properties and physical properties, such as enhancing the stability and durability of materials. In the field of agriculture, it can be used to develop new pesticides, improve the efficacy of insecticides and weeding, and reduce the harm to the environment. This substance is of great value in many fields. With the deepening of research, its application prospects will be broader, and it is expected to bring new opportunities for the development of various industries and promote the progress of technology and industry.

Research & Development

In recent years, I have dedicated myself to the research of P Bromobenzotrifluoride. This compound has unique properties and wide uses, and has potential value in many fields.
At the beginning, it was difficult to explore its synthesis method. The screening of raw materials and the regulation of reaction conditions all need to be carefully considered. After repeated tests, a suitable path was obtained, and the yield was gradually improved.
Then study its properties, analyze its structure and characteristics. Observe its stability and activity changes in different environments to clarify its inherent laws.
At present, this research result has shown signs. In industrial production, it is expected to become an efficient raw material; in the field of scientific research, it can be the cornerstone of new exploration. However, there is still a long way to go, and many directions need to be expanded, such as optimizing the synthesis process to reduce costs, and digging deeper into the characteristics to expand the application. I should make unremitting efforts to promote the development of this compound and add new color to both academia and industry.

Toxicity Research

Nowadays, there is a chemical called P-Bromobenzotrifluoride. I am a chemical researcher and study its toxicity. The toxicity of this substance is related to the safety of everyone and cannot be ignored.
After many experiments, P-Bromobenzotrifluoride has certain toxicity. It may enter the body through respiration, damaging the lungs and organs, causing respiratory diseases; it can also penetrate the skin, seep into the bloodline, and disrupt the physiology of the human body. Looking at its effects on animals, rats, rabbits, etc., after exposure to this substance, they often appear restless and anorexic, and their organs will be damaged for a long time.
In order to ensure the safety of everyone, strict protection measures should be set up where this chemical is produced and used. The operator must wear professional protective equipment to prevent its harm. And the discharge and disposal of this thing also need to be cautious, so as not to let it pollute the environment and harm all living beings. Our chemical researchers should make unremitting research to find a better way to reduce its toxicity and harm, and be used by the world to avoid its harm.

Future Prospects

If P-Bromobenzotrifluoride, it is also a chemical thing. I am researching it, hoping that it will not be developed in the future. The properties of this compound are not special, or it can be used in new research. Not yet, I hope to be able to refine its chemical properties, make good use of its characteristics, and use it in the new way. Or it can be used in the field of materials to make special materials, used in aerospace and other fields, additive performance, and promote its progress. It is also expected to be able to improve its method, reduce its cost, increase the quantity, and benefit the general industry. In addition, the undeveloped P-Bromobenzotrifluoride, full of hope, we are diligent research to explore its possibility.

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Frequently Asked Questions

As a leading P-Bromobenzotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of P-Bromobenzotrifluoride?

P-bromotrifluorotoluene is a crucial raw material in organic synthesis and has a wide range of uses.
In the field of pharmaceutical synthesis, this compound plays a key role. It is used as the starting material for the preparation of many drugs. Through a series of delicate chemical reactions, molecular structures with specific pharmacological activities can be constructed. For example, in the synthesis of some antidepressant drugs and cardiovascular drugs, P-bromotrifluorotoluene can be used as a key intermediate. Through halogenation reaction, nucleophilic substitution reaction and other steps, specific functional groups can be ingeniously introduced to achieve the construction of target drug molecules. Due to its unique chemical structure, it can endow drugs with better lipid solubility and stability, and improve the bioavailability of drugs.
In the field of pesticides, P-bromotrifluorotoluene is also indispensable. It can be used to synthesize a variety of high-efficiency and low-toxicity pesticides. After reacting with other organic reagents, compounds with excellent insecticidal and bactericidal properties can be prepared. Such pesticides can not only effectively control crop diseases and insect pests, ensure crop yield and quality, but also have relatively little impact on the environment and ecology due to their low toxicity, which is in line with the development needs of today's green agriculture.
In addition, in the field of materials science, P-bromotrifluorotoluene also has its uses. When synthesizing high-performance polymer materials, it can be introduced into the polymer main chain or side chain as a functional monomer, giving the material unique properties, such as excellent corrosion resistance and heat resistance. These high-performance materials are widely used in high-end fields such as aerospace, electronics and appliances, and help the development of related industries.
P-bromotrifluorotoluene, with its unique chemical properties, plays an irreplaceable role in many fields such as medicine, pesticides and materials science, promoting technological progress and industrial development in various fields.

What are the physical properties of P-Bromobenzotrifluoride?

P-Bromobenzotrifluoride, or p-bromotrifluorotoluene, is an important compound in organic chemistry. Its physical properties are unique and of great research value.
This substance is mostly colorless to light yellow liquid at room temperature and pressure, and it looks clear and translucent. Its boiling point is about 195-197 ° C. This boiling point enables it to realize gas-liquid conversion at a specific temperature environment, providing a basis for related chemical operations such as distillation separation. The melting point is about -16 ° C, indicating that at lower temperatures, it will condense from liquid to solid.
The density of p-bromotrifluorotoluene is about 1.64 g/cm ³, which is relatively dense compared to water. If mixed with water, it will sink to the bottom of water. It has a certain degree of volatility and can evaporate slowly in the air, emitting a special odor. The substance is insoluble in water, but it can be miscible with many organic solvents such as ethanol, ether, acetone, etc. This solubility is convenient for selecting suitable solvents to promote the reaction in organic synthesis reactions.
In addition, the vapor pressure of p-bromotrifluorotoluene has a corresponding value at a specific temperature, which is related to its existence in the gas phase and the possibility of participating in the reaction. At the same time, its refractive index also has a specific index, and the refractive index can be used as an important reference for identifying the purity and concentration of the substance. Under the influence of external conditions such as light and heat, its physical state and related properties may change, so it is necessary to pay attention when storing and using.

What is the chemistry of P-Bromobenzotrifluoride?

P-Bromobenzotrifluoride, or p-bromotrifluorotoluene, is an important raw material in organic synthesis. Its chemical properties are unique and it exhibits distinct characteristics in many chemical reactions.
The bromine atom in this compound is highly active and can often participate in nucleophilic substitution reactions. When encountering nucleophilic reagents such as alkoxides and amines, the bromine atom is easily replaced by nucleophilic reagents, thus forming novel carbon-heteroatomic bonds. For example, when reacting with alkoxides, corresponding ether compounds can be formed; when reacting with amines, nitrogen-containing derivatives can be obtained. The occurrence of these reactions is mostly due to the benzene ring connected to the bromine atom. Affected by the electron-withdrawing effect of trifluoromethyl, the bromine atom is easier to detach, which is conducive to the attack of nucleophilic reagents. The presence of
trifluoromethyl also endows the compound with unique properties. Because of its strong electron absorption, the electron cloud density of the benzene ring is reduced, so in the electrophilic substitution reaction, compared with benzene, its activity is significantly reduced. However, once electrophilic substitution occurs, because trifluoromethyl is the meta-locator, the electrophilic reagents are more inclined to attack the position between the benzene rings.
P-Bromobenzotrifluoride still has certain chemical stability and can resist the action of some weak oxidizing agents and reducing agents. However, under certain conditions, such as the presence of strong oxidizing agents, trifluoromethyl may be oxidized, but the conditions required for such reactions are usually more demanding.
In addition, the physical properties of the compound, such as boiling point, melting point, solubility, etc., are also closely related to its chemical properties. It is insoluble in water, but soluble in common organic solvents. This solubility characteristic is of great significance in the reaction operation and product separation of organic synthesis.
In summary, P-Bromobenzotrifluoride exhibits unique chemical properties due to the synergistic effect of bromine atoms and trifluoromethyl. It is widely used in the field of organic synthesis and provides a key basic raw material for the creation of various organic compounds.

What is the preparation method of P-Bromobenzotrifluoride?

To prepare p-bromotrifluorotoluene (P-Bromobenzotrifluoride), there are two common methods.
First, p-bromotoluene is used as the starting material and is obtained by two steps of side chain halogenation and fluorination. First, p-bromotoluene is reacted with halogens (such as bromine or chlorine) under the presence of light or initiators under heating conditions, so that the hydrogen on the side chain methyl is gradually replaced by halogens to form p-bromobenzyl halides. This reaction process requires temperature control and halogen dosage to prevent over-halogenation. Subsequently, the prepared p-bromobenzyl halide reacts with anhydrous hydrogen fluoride (HF) in the presence of catalysts (such as Lewis acids such as antimony pentachloride), and the halogen is replaced by fluorine atoms. After separation and purification, p-bromotrifluorotoluene can be obtained. In this way, the raw materials are easily available, but the selectivity of the side chain halogenation step is poor, there are many side reactions, and the product separation is complicated.
Second, trifluorotoluene is used as the starting material and directly brominated. Trifluorotoluene is reacted with bromine in the presence of a catalyst (such as iron or iron tribromide). The brominating agent bromine undergoes an electrophilic substitution reaction with trifluorotoluene. Because trifluoromethyl is the meta-locator, the main by-products of bromide are generated. However, appropriate regulation of the reaction conditions, such as catalyst dosage, reaction temperature and time, can improve the selectivity of p-bromotrifluorotoluene. After the reaction is completed, the products are separated and purified by distillation, extraction and This method is simple, but the cost of trifluorotoluene is high, and the reaction conditions are strict.
The method of preparing p-bromotrifluorotoluene has its own advantages and disadvantages. The actual preparation needs to be based on the availability of raw materials, cost, product purity requirements and other factors to comprehensively consider and choose the appropriate method.

What are the precautions in storage and transportation of P-Bromobenzotrifluoride?

P-bromotrifluorotoluene is also an organic compound. During storage and transportation, many matters need to be paid attention to.
First storage, this substance should be stored in a cool and ventilated warehouse. Because the warehouse is cool, it can avoid abnormal chemical reactions caused by heat, and it is well ventilated to dissipate harmful gases that may accumulate to prevent danger. Keep away from fires and heat sources, both of which are prone to combustion and explosion. The open flame of the kindling and the high temperature of the heat source can cause P-bromotrifluorotoluene to reach the ignition point or cause it to decompose, causing accidents.
Furthermore, it should be stored separately from oxidants and alkalis, and must not be mixed. The oxidizing agent has strong oxidizing properties. The chemical properties of alkalis are different from those of P-bromotrifluorotoluene. The mixture of the two is prone to chemical reactions, or causes material deterioration, or produces dangerous products. And the storage area should be equipped with suitable materials to contain the leakage, in case of leakage, it can be collected in time to minimize the harm.
As for transportation, it is necessary to ensure that the packaging is complete and safely loaded before transportation. If the packaging is damaged, P-bromotrifluorotoluene is easy to leak during transportation, polluting the environment and endangering the safety of transportation personnel. It should travel according to the specified route and do not stop in densely populated areas, residential areas, etc. Because the substance may be toxic, corrosive and other hazards, if an accident occurs in such areas, the impact will be wide and the consequences will be unimaginable. During transportation, it is necessary to prevent exposure to the sun, rain and high temperature. Exposure and high temperature can change the physical and chemical properties of substances, and rain may cause damage to the packaging and cause leakage. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment for emergencies. In this way, the safety of storage and transportation can be guaranteed.