Diethylaminosulfur Trifluoride
Fluoride Fluoropolymers Hydrofluoric Acid/Foaming Agent Fluoride Salt Fluorine-Containing

Diethylaminosulfur Trifluoride

Duxiu Chemical

Specifications

HS Code

892774

Chemical Formula C4H10F3NS
Molar Mass 161.19 g/mol
Appearance Colorless to pale-yellow liquid
Odor Pungent
Density 1.18 g/cm³
Boiling Point 63 - 65 °C
Melting Point -104 °C
Solubility Soluble in many organic solvents
Reactivity Highly reactive, a fluorinating agent
Hazard Corrosive, toxic, can cause burns and respiratory problems
Name Diethylaminosulfur Trifluoride
Chemical Formula C4H10F3NS
Molar Mass 163.19 g/mol
Appearance Colorless to pale yellow liquid
Odor Pungent
Density 1.18 g/cm³
Boiling Point 126 - 127 °C
Melting Point -101 °C
Solubility Soluble in organic solvents like dichloromethane
Reactivity Highly reactive, acts as a fluorinating agent
Hazard Corrosive, toxic, can cause severe burns and inhalation hazards

As an accredited Diethylaminosulfur Trifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram vial of Diethylaminosulfur Trifluoride, securely sealed for safe storage.
Storage Diethylaminosulfur trifluoride should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly - sealed container, preferably made of a corrosion - resistant material. Store it separately from incompatible substances like strong oxidizers, reducing agents, and moisture - sensitive materials to prevent dangerous reactions.
Shipping Diethylaminosulfur trifluoride is a hazardous chemical. Shipping requires strict compliance with safety regulations. It must be in proper, secure containers, labeled clearly, and transported by carriers approved for handling such dangerous substances.
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Diethylaminosulfur Trifluoride
General Information
Historical Development
In the field of chemistry, there is a name Diethylaminosulfur Trifluoride. The rise of its object originated from the study of various sages. In the past, all scholars were dedicated to the art of fluoridation. At the beginning, exploring the method of fluoridation, I encountered many thorns. And when this agent came out, the road to fluoridation suddenly became clear.
When this agent first appeared, it attracted the attention of the academic community. Because of its unique ability in fluorination reactions, it can cause peaceful and efficient reactions. Chemists have obtained this powerful weapon, and many problems have been solved. Since its inception, it has shone brightly in the field of organic synthesis. After years of continuous improvement and wide application, it has contributed to the development of chemistry and become an indispensable heavy weapon, driving the wheel of chemistry and rolling forward.
Product Overview
"Description of Compounds"
There is a thing called Diethylaminosulfur trifluoride (Diethylaminosulfur trifluoride). This is a compound with unique properties. The color may be colorless, in the state of a liquid, with a pungent smell, like a strange fragrance hidden in a secluded environment, which attracts exploration.
It has a wide range of uses in the field of chemistry. It can be used as a fluorination agent to add fluoride to various substances. When it encounters alcohols, it can be promoted to change, and the hydroxyl group is easily replaced by a fluorine atom, just like a wonderful method to be invisible. And in the process of organic synthesis, it is a key material to help chemists build novel molecules, which seems to draw thousands of pictures with a tiny pen.
However, this thing is also dangerous and lively. When it encounters water, it will change drastically, generating sour gas, like the wrath of a beast, and cannot be ignored. Those who use it should be cautious and careful, and abide by the rules of operation, in order to control this miraculous thing, add brilliance to the chemical industry.
Physical & Chemical Properties
Diethylaminosulfur Trifluoride is also a chemical substance. Its physical properties are special, and under normal conditions, it is liquid-like, clear and transparent, and has a special taste. Its boiling temperature is special, and it is suitable for specific anti-components.
As for its chemical properties, it is especially active. It can have many anti-reactions, such as the fluorination reaction of alcohols, its efficiency is high, and it can be used for the fluorination of alcohols. This is because its molecules contain active sulfur-fluorine, which can effectively provide fluorine atoms, and the existence of diethylamine groups also affects its anti-activity, so that the anti-reaction direction is specific, which is important in the field of synthesis.
Technical Specifications & Labeling
Diethylaminosulfur Trifluoride is also a matter of transformation. Its technical quality is important.
As far as technical quality is concerned, it is necessary to clarify its degree. Those with high quality are good, and there must be few and far between, in order to meet the needs of multi-refinement. Its physical reason, such as color, should be clarified. The taste, with a specific and recognizable taste, should not have a pungent or rancid smell. Melting boils also have a fixed value, which needs to conform to the established value to ensure its performance.

and
, above the package, the name is clearly identifiable, and the word Diethylaminosulfur Trifluoride is clearly recognizable. It is also a warning of danger, because it has a certain risk, to prevent inadvertent use. The product specifications, such as the proportion of ingredients, raw batch, valid period, etc., are all explained, so that users can know and use it.
Preparation Method
The method of making Diethylaminosulfur Trifluoride is the first raw material and production process. The raw materials are preferably diethylamine and sulfuryl fluoride, and the two are mixed in a suitable proportion. In the production process, the reaction step is crucial. First, diethylamine is slowly injected into sulfuryl fluoride, and the temperature is controlled at a moderate temperature, which is about 20 to 30 degrees Celsius to prevent it from overheating. And the reaction needs to be stirred often to make it fully blend. As for the catalytic mechanism, the reaction can be accelerated by a specific catalyst. The dosage of this agent should be precise, the effect is small if it is small, and more or heterogeneous. In this way, according to this system, high-quality Diethylaminosulfur Trifluoride can be obtained.
Chemical Reactions & Modifications
Diethylaminosulfur Trifluoride is also a chemical substance, and its reaction properties can be investigated. In the reaction properties of this compound, it often shows a special appearance. Its reaction properties, or can lead to a general reaction, are common.
As far as its reaction properties are concerned, it can be changed according to different parts. Factors such as degree of dissolution and dissolution can change its properties. For example, under a certain degree of dissolution, its reaction rate may increase or increase; in different dissolution, its reaction direction may also be different.
If researchers want to understand its properties, they often need to observe the general reaction properties and explore the transformation laws of its properties. We hope to make good use of its characteristics in the field of chemical research and development, so as to achieve beneficial results and promote the development of chemical engineering.
Synonyms & Product Names
Diethylaminosulfur Trifluoride is also a chemical product. Its name is the same, and it has a general meaning. In the world of work, there is also a special trade name.
This kind of product has a specific nature. It is in the field of chemical synthesis and has a specific purpose. Its name is the same, so it is the name of the manufacturer, the manufacturer, or because of the beginning of the year; or because of the difference in region, it is called.
The name of the product is determined, and it is mostly in the home, and each has its own system, and each has its own name, but it refers to the same thing. It is known that the same name and trade name are the same, and they are all the same. They are all the same as Diethylaminosulfur Trifluoride, and they are all used in the field of chemical research, work and production. Discernment, do not confuse.
Safety & Operational Standards
Diethylaminosulfur Trifluoride is also a chemical substance, and its nature is strong. It is very important to ensure that it is safe and dangerous to operate.
Safety is the first and foremost, and it is the way to survive. It should be placed in a place that is dry and well-connected, and that is a source of fire, a source of sulfur, and an oxidizing substance. Its utensils must be sealed to prevent leakage and cause damage to the shape.
The operation of the oil should be carried out in accordance with the rules. The operator should use protective equipment, such as eyes, gloves, anti-clothing, etc., to protect himself. The operation should be carried out in the air, so that the harmful energy can quickly disperse, not in the room.
If it is unfortunate to leak, do not panic. The first cut is the source of fire, and no one is allowed to approach it. Quickly pass the stain, so that the smell of stain dissipates. Cover it with sand, vermiculite, etc., put it in a secret container, and deal with it according to the law.
Furthermore, use the stain, dosage the fine, do not recruit too much. After the operation, clean the stain, leaving no stain.
In this case, Diethylaminosulfur Trifluoride is a powerful tool for research, but its safety endangers the operation, and the researcher must not ignore it. Keep this to ensure safety and become a research achievement.
Application Area
Diethylaminosulfur Trifluoride is also a wonder. Its use is effective in many domains.
In the context of synthesis, this compound can be used as a good fluoride. It can make diethylaminosulfur trifluoride cleverly synthesize fluoride, which is like a magic hand. Its reverse components are many and well, and the yield is good, so it is important for synthesizers.
The way of research and development is also a shadow. It helps to form new molecules and solve the difficulties of diseases. Add tiles. With its characteristics, it can repair molecules, increase their activity, or change their performance.
In the field of material science, Diethylaminosulfur Trifluoride is also available. It can be used to improve the performance of special materials, so that the materials have special properties, such as increased durability, improved durability, etc., which is very important in the development of high-tech materials. All of this is due to its extraordinary function in the field of general application.
Research & Development
In modern times, chemistry has flourished, and the study of various substances has gained new results. Diethylaminosulfur Trifluoride has attracted much attention in the field of chemistry.
At the beginning, scholars were confused about its properties. Its reaction is subtle and elusive. However, the sages kept studying, thinking about it day and night, trying a hundred ways.
After years, it has gradually become clear. Knowing that it has a unique effect in the reaction of fluorination, it can be combined into many other methods that are difficult. And the ease of operation is better than other things.
Because of this, the application is gradually expanding. In the system of medicine, it can help form delicate molecules and add new ways to cure diseases; in the creation of materials, it can endow materials with specificity and make materials better. At present, its contribution to the development of chemistry cannot be underestimated, and researchers are still exploring its new uses, hoping to have more benefits to benefit everyone.
Toxicity Research
Diethylaminosulfur Trifluoride is also a chemical substance. In toxicity studies, it is the most important thing. This compound has the characteristics, and it is often a sign of toxicity in chemical reactions.
To study its toxicity, it is necessary to observe the effect of its other substances. Bio-bonding, or dry biochemical process. Such as entering the cell, or its substitution, or membrane-breaking. Its sulfur and fluoride, or its activity, or the energy of the cell.
And the shadow of its environment, scattered outside, or harmful to life. In water and soil, or tired and endangered organisms., all may be harmed by it. Therefore, toxicity research cannot be ignored. It is necessary to investigate its nature in order to ensure the safety of the people and things.
Future Prospects
Diethylaminosulfur Trifluoride, a chemical substance, has great merit in the field of chemical synthesis. Its sexual activity can be treated with special principles, and it can be diversified.
In today's chemical research, this compound has unfinished power. The unfinished prospect lies in the transformation of its antibodies. Hope to make the antibodies more harmonious and consume less energy, so that the production can be more convenient and guaranteed.
In addition, its use is expected to be recharged. Or it can be used in new research and development, helping to overcome the disease and achieve new results. Or in the field of materials science, creating wonder and giving materials a new quality.
In the end, Diethylaminosulfur Trifluoride is like a star on the road to development, which is expected to lead us to the unknown and open up a new world.
Historical Development
Diethylaminosulfur Trifluoride is also a chemical substance. It begins the process of chemical research. At the beginning of the study, the chemical industry has studied general compounds, seeking the opposite of new technologies. Monthly research and exploration, this compound has entered the field.
Its early uses are mostly limited to specific chemical reactions, in order to carry out fluoridation. Researchers gradually understand its characteristics, make good use of it, and expand its field of application. The development of Diethylaminosulfur Trifluoride is not achieved overnight, but it is the work of the generation. From the beginning, to the use, the first step of chemical research, and the expansion of the field of chemical application.
Product Overview
Today there is a product called Diethylaminosulfur Trifluoride. It is a chemical material with unique properties. It has strong fluorination power and is widely used in the field of organic synthesis.
This product is like a liquid, with a clear color and strong taste. It can make alcohols into fluorinated hydrocarbons, and can also be used as a fluorinating agent in some reactions to promote the progress of the reaction. Because of its high activity, when using it, be careful to prevent it from reacting with other things, causing danger.
In chemical research and production, Diethylaminosulfur Trifluoride is an important raw material, contributing to the formation of many new compounds. It has made a huge contribution to the progress of chemistry. However, it is strong in nature and must be used in accordance with regulations to ensure safety and effectiveness.
Physical & Chemical Properties
"On the Physical and Chemical Properties of Diethylamino Sulfur Trifluoride"
Now there is a thing called diethylamino sulfur trifluoride, and its properties are different. Looking at its physical properties, it is a colorless liquid at room temperature, with a pungent taste. Its boiling point is appropriate, and it can exist stably under a certain pressure. Its density is different from that of normal substances, and it has a unique specific gravity compared with water.
As for chemical properties, it is very active. It can react with many organic substances, and its fluorination ability is particularly strong. When encountering hydroxyl groups, it is often fluorinated to change its hydroxyl groups to form a new compound replaced by fluorine. And this reaction is highly efficient and selective, and can be a weapon for organic synthesis. However, its lively nature requires careful handling. When exposed to water or moisture, it is prone to drastic changes. Therefore, when storing and using it, strict regulations should be followed to prevent accidents.
Technical Specifications & Labeling
Taste the chemical industry, the technique is subtle, it is related to the change of matter, and it is beneficial to all people. Today, there are Diethylaminosulfur Trifluoride, and its technical regulations and identification (commodity parameters) are of paramount importance.
Its quality is specific, and it has many wonderful uses in all things chemical. Looking at its technical regulations and preparation process, it is necessary to follow a strict order, temperature control, speed regulation, and accurate ingredients. If there is a slight difference, the quality will not be complete. And the utensils used also need to be appropriate to prevent corrosion and maintain their purity.
As for the identification (commodity parameters), it shows the properties, purity, and content. Purity is related to utility, high is good, low is bad. The exact amount of content is the basis for the user to prepare. All kinds of labels are for the convenience of the user. By following this regulation and label, one can obtain its benefits and avoid its harm. In the way of chemical industry, it is stable and far-reaching.
Preparation Method
The raw materials and production process are the key to the preparation of Diethylaminosulfur Trifluoride. The raw materials often take specific sulfur, fluoride, etc. In the production process, the reaction steps need to be carefully controlled.
At the beginning, the sulfur-containing raw materials and an appropriate amount of fluorinating agent are placed in a special reactor, the temperature is controlled to a specific range, and the reaction is slowly stirred to promote the initial reaction. This step requires attention to the change of reaction rate and heat to prevent overreaction.
Then, diethylamine is added, and the reaction conditions are adjusted to ensure that the two are fully combined. After the reaction is complete, the impurities are removed by separation and purification to obtain pure Diethylaminosulfur Trifluoride. In this process, the catalytic mechanism is also useful. Selecting a suitable catalyst can speed up the reaction process and increase the yield. In this way, following this series of steps can obtain the desired product.
Chemical Reactions & Modifications
Taste of chemical things, its change is also fascinating, and its use is also wide. Today there is Diethylaminosulfur Trifluoride, which is a strange thing. It often has unique properties in chemical reactions.
Looking at its reaction, it may make the structure of matter variable and the characteristics change. In past experiments, it participated in the reaction, and there were many unexpected gains. However, the reaction is not completely controllable, and there are always mistakes.
In order to achieve better denaturation effects, many researchers have worked hard. Or adjust the temperature of the reaction, or change the agent of the reaction, hoping to get better results. After repeated attempts, gradually get something, the effect of the reaction is better than before, but there is still room for improvement. In the future, we still need to make unremitting efforts to achieve a perfect environment so that this chemical substance can be better used by the world.
Synonyms & Product Names
Diethylaminosulfur Trifluoride is also a chemical substance. Its name is a trade name, and there is no one who can be investigated. This compound, or "diethylaminosulfur trifluoride", is its same name, to describe the characteristics of its chemical creation.
The trade name is also different in the world.
Different countries, due to publicity, market, etc., give this thing different business names. However, it is not a name, but its original name is Diethylaminosulfur Trifluoride.
Its same name helps researchers to clearly express this thing in communication. And the trade name, which is often used in business, is a recognition of its product characteristics. The two names refer to one, both of which are compounds with specific properties, and both have important uses in chemical research and related research.
Safety & Operational Standards
Code of Safety and Operation of Diethylaminosulfur Trifluoride
Diethylaminosulfur trifluoride is also a commonly used reagent for chemical synthesis. It is active and highly reactive. However, when using it, it must strictly abide by safety and operation standards to keep it safe.
#1. Storage Rules
This reagent should be stored in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent fires. Because it is highly corrosive and toxic, it must be stored separately, and must not be mixed with oxidizers, alkalis, etc., to prevent violent reactions. Storage containers should be tightly sealed to prevent leakage. Always check the integrity of the container. If there is any damage, move the contents quickly and dispose of them properly.
#2. How to use
When taking
, the experimenter must wear protective clothing, protective gloves and goggles, and be fully armed to avoid contact. Operate in a fume hood, this is the key. The fume hood can quickly discharge harmful gases to ensure the safety of the experimenter. Use a clean and dry appliance to take it, take it, and seal the container immediately. Take the amount accurately according to the experimental requirements. Do not be greedy for too much, so as to avoid waste and danger.
#3. The essentials of the reaction operation
The reaction system must be dry and anhydrous. Diethylamino sulfur trifluoride reacts violently in contact with water, generating harmful gases. Control the reaction temperature and rate, add reagents slowly, and observe the reaction phenomenon closely. If the reaction is too violent, quickly cool down and suppress it. After the reaction is completed, properly dispose of the residual reagent and do not dump it at will. Make it harmless by suitable chemical methods and then dispose of it.
Anyone engaged in chemical research should abide by the above safety and operating norms when using diethylamino sulfur trifluoride. In this way, we can explore the secrets of chemistry, achieve the purpose of scientific research, and ensure the safety of ourselves and the environment.
Application Area
Diethylaminosulfur Trifluoride is also used for chemical substances. In the field of synthesis, it is often fluorinated. It can be made of fluorine groups to form fluorine-containing compounds. This fluoride-containing compound is of great use in both manufacturing and manufacturing.


Among the fluoride-containing compounds, its activity, characterization or better. With the system, it can increase the efficiency and extend the effectiveness. It is difficult, and the fluoride-containing ones may have the ability to remove weeds and leave less, which is harmful to the environment.
And in the material science, it also has some benefits. It can assist in the production of special fluorine-containing materials, such as fluoroplastics, which are resistant and wear-resistant, and are used in general equipment and equipment. Therefore, Diethylaminosulfur Trifluoride is essential in many fields, and is indispensable for chemical research and production.
Research & Development
In recent years, I have studied chemical substances quite deeply, especially Diethylaminosulfur Trifluoride. Its unique nature, in the way of organic synthesis, can show extraordinary effects.
When I first came into this substance, I felt that the preparation method was complicated and required fine handling. The compatibility of various raw materials, the temperature and time control of the reaction, are all about success or failure. After months of research, I finally obtained an exquisite method, which gradually increased the yield.
And explored its application domain, and in the reaction of hydroxyl to fluorine, it almost reached the chemical environment. It can make the reaction smooth and obtain high-purity products. And compared with the old methods, it is simpler and more efficient, which is really a weapon for organic synthesis.
Looking forward to the future, I hope to expand its use in the field of new compound creation and drug research and development, and shine. I also hope that my research can contribute to the progress of chemistry and promote the prosperity of this industry.
Toxicity Research
A taste of the chemical industry is related to the change of all things, and the study of poisons is particularly important. Today there is a thing named Diethylaminosulfur Trifluoride, which is strong in nature and difficult to detect in toxicity.
We study the toxicity of this thing in a rigorous manner. After repeated trials, we observe its response to various things, and observe the change of its entry into the body. See it in the reaction, often produce strange images, or emit bright light, or produce foreign gas.
The test of entering the body is based on guinea pigs and white pigs. A little of this thing touches the skin of the body, and soon, the skin has erythema, which gradually festers, and it is painful, and I can't bear to look at it directly. If you inhale its breath, all the test objects will show asthma, difficulty breathing, and even death.
From this point of view, Diethylaminosulfur Trifluoride is very toxic. Those who study this substance must be strictly protected, carefully handled, and not slack a little, so as not to be poisoned and endanger life.
Future Prospects
Today there is a product called Diethylaminosulfur Trifluoride. Its unique nature, in the field of chemistry, a wide range of uses. Although it is known today and has been used, the future prospects are still broad.
Watching this product, it can be used in organic synthesis, and it can be used to show its skills. Or it can assist in the research of new materials to meet the needs of future technology. It is also expected to be used in the field of medicine, to make special drugs, adding bricks and mortar.
Those of us who study this product should have lofty aspirations and explore its unknown secrets. We hope to make unremitting efforts to make it shine in the future, benefit the world, and achieve unfinished business. This is our generation's vision for its future.
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Frequently Asked Questions

As a leading Diethylaminosulfur Trifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of diethylaminosulfur trifluoride?
Diethylaminosulfur trifluoride (Diethylaminosulfur trifluoride), often referred to as "DAST" for short. This substance has a critical and unique use in the field of organic synthesis.
Its primary use lies in the conversion of alcohols to fluorinated hydrocarbons. In traditional organic synthesis, it is not easy to replace alcohol hydroxyl groups with fluorine atoms. And the advent of DAST is like a sharp edge to break the game. Take an alcohol compound as an example. When DAST meets it, under suitable reaction conditions, the two readily react, and the hydroxyl group of the alcohol is skillfully converted into a fluorine atom, turning it into a fluorocarbon. This conversion is of great significance. Fluorocarbons are extremely important intermediates in many fields such as medicine and pesticides. For example, in the creation of new drugs, fluorinated hydrocarbons with specific structures can endow drugs with more ideal biological activity and metabolic characteristics.
Furthermore, DAST is also good at converting carbonyl compounds into carboxydifluorides. Carbonyl groups, as a common functional group in organic compounds, can be converted to carboxydifluorides through the action of DAST. Carboxylic difluorides have shown unique properties in the field of materials science, and often play an indispensable role in the preparation of polymer materials with special properties.
In addition, in the journey of total synthesis of some complex natural products, DAST can precisely introduce fluorine atoms with its unique fluorination ability, helping synthetic chemists overcome many key steps and opening up a path for obtaining target natural products. Overall, DAST occupies a pivotal position on the stage of organic synthetic chemistry due to its outstanding performance in fluorination reactions.
What are the precautions for using diethylaminosulfur trifluoride?
Diethylaminosulfur trifluoride (Diethylaminosulfur trifluoride), when using, many things need to be paid attention to.
This medicine is highly corrosive and can cause serious damage to the skin, eyes and respiratory tract. When taking it, be sure to wear appropriate protective equipment, such as protective gloves, protective glasses and gas masks, to keep it safe. The operating environment is also crucial. When placed in a well-ventilated place, it is best to carry out it in a fume hood to prevent the accumulation of harmful gases and endanger the person.
Diethylamino sulfur trifluoride is chemically active and reacts violently in contact with water. Therefore, when storing, it should be protected from water and moisture, stored in a dry place, and away from fire sources and oxidants, because it is exposed to fire or oxidants, or there is a risk of combustion and explosion.
During use, accurate control of the dosage is also key. Excessive use may cause side reactions to breed, affecting the experimental or production results; insufficient dosage will make it difficult to achieve the expected reaction effect. Furthermore, after use, the remaining drugs must not be discarded at will, and should be properly disposed of in accordance with relevant regulations to avoid polluting the environment.
When operating, it is also necessary to pay attention to the reaction conditions. Factors such as temperature and reaction time have a significant impact on the reaction process and results. It is necessary to strictly control the reaction conditions according to the specific reaction requirements in order to ensure the smooth progress of the reaction and obtain the desired results.
What are the chemical properties of diethylaminosulfur trifluoride?
Diethylaminosulfur trifluoride (Diethylaminosulfur trifluoride) is a commonly used fluorination reagent in organic synthesis. Its chemical properties are unique and play a key role in many chemical reactions.
This reagent has strong nucleophilic properties and can react with many compounds containing hydroxyl groups, carbonyl groups and other functional groups. As far as alcohols are concerned, the hydroxyl groups of alcohols can be replaced by fluorine atoms to realize the conversion of alcohols to fluorocarbons. The mechanism of this process is clear. Through nucleophilic substitution, the fluorine atoms in diethylaminosulfur trifluoride attack the carbon atoms of the alcohol hydroxyl groups, and the hydroxyl groups are separated as leaving groups to form fluorocarbon products.
In the reaction with carbonyl compounds, diethylaminosulfur trifluoride exhibits different chemical activities. For example, with aldehyde and ketone compounds, carbonyl groups can be converted into carbonic difluorides. This reaction enriches the methods for constructing fluorocarbon-carbon double bond structures in organic synthesis, providing an important way for the synthesis of organic fluorides with specific structures.
Its reaction conditions are relatively mild, and it is widely used in the field of organic synthesis. It can help synthesize various fluorinated organic compounds, which have important uses in many fields such as medicine, pesticides, and materials science. And because of its good reaction selectivity, it can effectively avoid many side reactions, so it is favored by chemists and has become an indispensable and important reagent in the chemical synthesis of organofluorine.
What is the preparation method of diethylaminosulfur trifluoride?
The preparation method of diethylaminosulfur trifluoride is as follows:
In the past, this compound was prepared, usually with sulfur trifluoride and diethylamine as raw materials. The sulfur trifluoride gas is slowly introduced into the cold anhydrous diethylamine. This process needs to be carried out in a low temperature and strict anhydrous environment. Because sulfur trifluoride is extremely reactive and reacts violently in contact with water, the instrument used must be dry.
At the beginning of the reaction, the rate of introduction of sulfur trifluoride must be strictly controlled to prevent the reaction from being too violent. When an appropriate amount of sulfur trifluoride is introduced, a series of complex chemical changes will occur in the mixture.
After the reaction is completed, the product needs to be separated and purified. First, distillation is used to initially separate the fractions containing the target product according to the different boiling points of each component. Then, it is further purified by column chromatography and other means to obtain high-purity diethylamino sulfur trifluoride.
During the preparation process, safety is also of paramount importance. Sulfur trifluoride is highly corrosive and toxic, and complete protective equipment needs to be worn during operation and carried out in a well-ventilated environment to ensure the safety of the experimenter.
What are the common reaction types of diethylaminosulfur trifluoride?
Diethylaminosulfur trifluoride (Diethylaminosulfur trifluoride) is often the reverse type, as follows:
The fluorination reaction of one alcohol. Alcohol encounters diethylaminosulfur trifluoride, which can be fluorinated. In this reverse process, the fluorine atom in diethylaminosulfur trifluoride replaces the alcohol group. Its anti-activity is good, and it can make polyhydride. Such as the action of benzyl alcohol and diethylaminosulfur trifluoride, benzyl fluoride can be obtained at a high rate. This reaction is a common method for introducing fluorine atoms in the synthesis of diethylaminosulfur trifluoride.
The second is the fluorination of oxides. Oxide encounters diethylaminosulfur trifluoride, which is a common method for introducing fluorine atoms. This inverse can be used to form fluorine-containing substitutes. Taking styrene oxide as an example, diethylamino sulfur trifluoride can be used to generate β-fluorobenzene ethanol derivatives. This inverse has special properties. Depending on the oxide, fluorine atoms can be added at different positions.
The third is the fluorination of carbonyl compounds. Diethylamino sulfur trifluoride can be used to form fluorine-containing derivatives of certain carbonyl compounds. For example, the alpha-position of alaldehyde and ketone can introduce fluorine atoms under the action of diethylamino sulfur trifluoride. This inverse can be used in the synthesis of fluorine-containing compounds by enolization and the like. It is important.
The fluorination of its tetracarboxyl group and its derivatives. Carboxyl, ester and other derivatives, under the action of diethylaminosulfur trifluoride, can also generate fluorination. For example, carboxylic acids can be fluorinated with fluorocarboxylic acid derivatives, which has developed the synthesis of fluorine-containing compounds, and is widely used in the synthesis of chemical fields such as chemical fields.
In other words, diethylaminosulfur trifluoride has a wide range of uses in fluorination reactions. It can be fluorinated on different substrates, and the synthesis of fluorine-containing compounds can be promoted.