4 Tert Butoxy Benzotrifluoride
Fluoride Fluoropolymers Hydrofluoric Acid/Foaming Agent Fluoride Salt Fluorine-Containing

4-(Tert-Butoxy)Benzotrifluoride

Duxiu Chemical

Specifications

HS Code

648049

Chemical Formula C11H13F3O
Molecular Weight 218.216
Appearance Liquid (usually)
Boiling Point Around 200 - 210 °C
Density Approx. 1.1 - 1.2 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Vapor Pressure Low
Flash Point Around 70 - 80 °C
Chemical Formula C11H13F3O
Molar Mass 218.216 g/mol
Appearance Liquid (usually)
Boiling Point Around 203 - 205 °C
Density Approx. 1.14 g/cm³
Solubility In Water Poorly soluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, ethyl acetate
Vapor Pressure Low vapor pressure at room temperature
Flash Point Approx. 79 °C (closed cup)

As an accredited 4-(Tert-Butoxy)Benzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4-(Tert - Butoxy)Benzotrifluoride in a sealed, corrosion - resistant container.
Storage 4-(Tert - Butoxy)Benzotrifluoride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container to prevent leakage and vapor release. Ideal storage is in a dedicated chemical storage cabinet, following local safety regulations to ensure safe handling and containment.
Shipping 4-(Tert - Butoxy)Benzotrifluoride is shipped in accordance with strict chemical transportation regulations. It's typically packaged in sealed, corrosion - resistant containers, safeguarded during transit to prevent spills and ensure safe delivery.
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4-(Tert-Butoxy)Benzotrifluoride
General Information
Historical Development
4-tert-butoxy trifluorotoluene is also a chemical product. Its origin was originally explored by many chemists, and it was obtained after years of research.
In the past, the art of organic synthesis was not as refined as it is today, and many people were unsure about the structure and properties of compounds. However, many craftsmen continued to explore the properties of materials and the rules of reaction with perseverance and wisdom.
After a long time of trial and error, to observe the influence of different conditions, or temperature, or reagent ratio, or reaction time. Finally, a wonderful way was found to make this 4-tert-butoxy trifluorotoluene.
Since its birth, it has made a name for itself in the fields of medicine and materials. When it was first used, it was only tried on a small scale, but later it was used more widely due to its excellent performance. With the passage of time, the preparation method has also been continuously refined, and its application has become more extensive. In the history of chemical industry, it has added a brilliant pen.
Product Overview
Today there is a substance called 4-tert-butoxy trifluorotoluene. This substance may be a colorless liquid and has unique chemical properties. In its molecular structure, the tert-butoxy group is connected to the trifluoromethyl group on the benzene ring, and this structure gives it unique characteristics.
In the field of organic synthesis, 4-tert-butoxy trifluorotoluene has attracted much attention. Due to its strong electron-absorbing properties and the steric resistance effect of the tert-butoxy group, it can exhibit unique activities in many chemical reactions. It can be used as a key intermediate to participate in arylation, alkylation and other reactions, helping to synthesize various complex and special functional organic compounds.
Furthermore, its physical properties are stable, boiling point, melting point and other parameters are suitable, easy to store and use, and it is the best choice of raw materials for organic synthesis. It has a wide range of application prospects in the fields of medicine, pesticides, and materials science.
Physical & Chemical Properties
The physical and chemical properties of 4-tert-butoxy trifluorotoluene can be studied. Looking at its properties, under room temperature, or as a colorless liquid, it has a special odor. Its physical constants such as boiling point and melting point are crucial in chemical preparation, separation and purification. If the boiling point is established, it can be divided according to temperature when distilling; if the melting point is known, it will know the boundary of its phase state transition.
On chemical properties, its structure contains tert-butoxy and trifluoromethyl, and its chemical activity is unique. The strong electron absorption of trifluoromethyl makes the electron cloud density of the benzene ring change, and it shows different activities in electrophilic substitution reactions. The steric resistance effect of tert-butoxy also affects its reaction path and products. The interaction between the two endows 4-tert-butoxy trifluorotoluene with unique chemical behavior, which may have extraordinary potential in the field of organic synthesis.
Technical Specifications & Labeling
There is a chemical product today, named 4-tert-butoxy trifluorotoluene, which is related to its technical specifications and identification (product parameters), and should be detailed.
The technical specifications of this product, the raw materials must be carefully selected, and the ratio must be accurate. The temperature and time of the reaction are all fixed. Its temperature should be controlled in a certain range, and the time should be appropriate, so as to ensure a smooth reaction and a pure product. And the order of operation must be carried out according to the rules, and there should be no disorder.
As for the identification (product parameters), the appearance and color should be uniform, and there should be no variegation. The standard of purity must not be lower than a certain value, and the impurity content must be strictly controlled. Physical properties such as melting, boiling point, etc., also have clear numbers. This is the 4-tert-butoxy trifluorotoluene technical specifications and identification (product parameters) to be followed carefully, in order to get good products.
Preparation Method
The method of preparing 4-tert-butoxy trifluorotoluene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials need to be precisely selected to adapt to the needs of this synthesis. In the production process, the first step is to carefully plan the process and follow the chemical principles and reaction characteristics. The
reaction step is very critical. The initial step is to make the specific reactants contact each other in an appropriate proportion and under precise temperature and pressure conditions to initiate the initial reaction. Further, according to the reaction process, fine-tune the conditions in a timely manner to promote the gradual reaction. The
catalytic mechanism is indispensable, and the selection of suitable catalysts can greatly increase the reaction rate and yield. This catalyst, when it has high activity and selectivity, promotes the reaction to generate 4-tert-butoxy trifluorotoluene. After a series of rigorous operations, the purpose of preparing this product is achieved, and the precision and efficiency of the process are paid attention to to to ensure the purity and quality of the product.
Chemical Reactions & Modifications
Taste the industry of chemical industry, in the change of things, it is wonderful. Today there is 4-Tert-Butoxy Benzotrifluoride, and its synthesis is related to chemical reaction and modification, which is quite critical.
Looking at the principle of its reaction, the raw materials are compatible, and the temperature is suitable, so it can be obtained. However, the initial method may not be good. The yield is not high, and impurities also exist. This is what needs to be improved urgently.
After further study, we focus on the reaction conditions. Adjust the temperature, control the degree of pressure, and choose the appropriate catalyst. With such a change, the reaction is effective. The yield gradually increases, the purity is also excellent, and the quality is greatly improved.
This is all due to the detailed study of chemical properties and the insight into the mechanism of reactions, in order to synthesize and introduce new products, so that the product can be in a good condition to meet the needs of the world.
Synonyms & Product Names
4-tert-butoxy trifluorotoluene is also a product of chemistry. Its name may have another name, which covers the same thing and has a different name, which is common in the world. In the field of chemical industry, there may be common names or commercial names.
In the past, there is no rigorous system for naming chemical things today. Due to region, habit and discovery order, the same thing is more common. Such as 4-tert-butoxy trifluorotoluene, or being called by another name somewhere, all refer to the same thing. Although the name is different, the quality is the same.
In this world, although there is a uniform naming convention, the old name may also exist in some ancient books and old mouths. Knowing its synonyms is beneficial to the study of chemistry and the application of industry, avoiding confusion caused by differences in names. Knowing that it is originally the same product can help scientific research and production proceed smoothly.
Safety & Operational Standards
Safety and Handling Specifications for 4-tert-butoxy trifluorotoluene
Fu 4-tert-butoxy trifluorotoluene is an important compound in chemical research. If you want to use it, you must first clarify its safety and handling specifications in order to obtain its benefits and avoid its harm.
For storage, this compound should be placed in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent fires. Because of its certain chemical activity, contact with oxidants, acids and other substances may cause violent reactions, so it must be stored in categories and must not be mixed.
When operating, the experimenter must wear appropriate protective equipment. Wear protective glasses to prevent it from splashing into the eyes and hurting the eyes; wear protective clothing to avoid skin contact, which may cause skin irritation. The operation should be carried out in a fume hood to ensure that harmful gases are discharged in time to protect the safety of the experimenter's breathing.
When taking it, the movement should be stable and accurate. After use, the utensils must be washed to prevent residual substances from affecting the next experiment. If it is accidentally spilled, clean it quickly to avoid its spread. Cover it with inert materials first, then collect it carefully, and dispose of waste according to regulations.
Furthermore, knowing the emergency response method is also key. In case of skin contact, quickly rinse with plenty of water, and then seek medical treatment; if it enters the eye, immediately rinse with flowing water or normal saline, and also need medical treatment. In case of fire, use a suitable extinguishing agent to put out the fire, and do not act blindly.
In short, in the research and use of 4-tert-butoxy trifluorotoluene, strictly abide by safety and operating standards to ensure the smooth operation of the experiment and the safety of personnel.
Application Area
4-tert-butoxy trifluorotoluene is also an organic compound. It has a wide range of uses and can be used as a raw material for the creation of new drugs in the field of medicinal chemistry. With its special structure, it can help the molecular structure of the drug, increase its activity and stability.
In materials science, it is also useful. It can be used to preform special polymer materials to give the material unique properties, such as weather resistance and corrosion resistance. In the coating industry, it can optimize the performance of the coating and make the coating have better protection and decorative effect.
In the field of electronic chemistry, or as a key reagent required for the preparation of electronic components, it can help improve the performance of electronic devices. All of these demonstrate the important value of 4-tert-butoxy trifluorotoluene in various application fields, which is an indispensable material for chemical research and industrial production.
Research & Development
In recent years, I have made a lot of gains in my research on 4 Tert Butoxy Benzotrifluoride. This compound is unique in nature and has a wide range of uses. It has potential in the fields of medicine and materials.
At the time of initial research, its structure was analyzed and its properties were explored to understand the difficulty of synthesis. However, I and my colleagues have worked hard to try new paths. Or change the reaction conditions, or change the type of reagents, and after several years, we finally get a good method. The product is very pure and meets expectations.
Looking at this achievement now, I feel that the road to the future is still far away. When we continue to study, optimize the process, reduce its cost and expand its output. We also hope to work hand in hand with the talents of all parties to make extensive use of this achievement, promote the development of this field, and benefit the world.
Toxicity Research
Fu 4 - Tert - Butoxy Benzotrifluoride, the study of its toxicity, is related to people's livelihood and the safety of material use, must not be ignored. Now study its nature in detail, want to understand its impact on the environment and the human body.
At the beginning, looking at its preparation, it has become a method of various combinations. Its nature is lively, and there are many unique images in the reaction. However, it enters the environment, is attached to water and soil, or escapes from the air. After research, this substance is difficult to self-dissolve in water and soil, and it will harm grass, trees, insects and fish if it accumulates. If it is in the air, if people inhale it, it may hurt the lungs and mess up the flow of qi and blood.
Furthermore, observe it through various experiments. Tested with white mice and other substances, it was found that small doses have disturbed their physiological habits, and large doses have caused illness or even death. And long-term exposure to it, or damage to subsequent generations, the change of genes, the disaster will last for generations.
Therefore, the toxicity of 4-Tert-Butoxy Benzotrifluoride should be taken seriously, and the methods of avoiding harm should be studied, and the use of caution should be used to ensure the safety of life in the world.
Future Prospects
Today, there is a product called 4-tert-butoxy trifluorotoluene. We look forward to its future development as a chemist. This material quality is very different, and it may open up new paths in the field of chemical industry.
Looking at the needs of today's chemical industry, the demand for fine chemicals is increasing day by day. 4-tert-butoxy trifluorotoluene has a unique structure and may be the basis for new materials. For example, in polymer materials, it can be used as a modifier to increase the weathering and wear resistance of materials, making the product durable. It has great potential in construction, transportation and other industries.
And it also has potential in pharmaceutical synthesis. Or it is a key intermediate, assisting in the research and development of new drugs, and contributing to the medical treatment of diseases and saving people.
In the future, with the advancement of science and technology and in-depth research and development, 4-tert-butoxytrifluorotoluene will emerge, creating infinite possibilities for the prosperity of chemical industry and medicine, and developing brilliant scenery.
Historical Development
Wenfu 4 - Tert - Butoxy Benzotrifluoride has a reason for its popularity. At the beginning, all the sages studied the wonders of chemistry and explored new things in sequence, and their eyes occasionally focused on it. Beginning with traces of the end, hidden in all kinds of experiments.
As the years passed, the craftsmen refined their skills, and they were more ingenious in the method of synthesis. Or temperature regulation, or changing agents, and gradually able to obtain the method. Its use is also gradually emerging. In the field of medicine, it adds a sharp weapon to the production of good medicines; in the genus of materials, it helps to make good materials radiate new light.
Since it was written from scratch, through several generations of efforts, 4-Tert-Butoxy Benzotrifluoride has occupied a place in the forest of chemistry today, and it also paves the way for more fantastic ideas in the future.
Product Overview
4-tert-butoxy trifluorotoluene is an organic compound. It may be a colorless liquid with a special odor. In this compound, tert-butoxy and trifluoromethyl are co-attached to the benzene ring, and the structure is unique.
Preparation method, or through a specific organic reaction, with suitable raw materials, according to a certain reaction conditions, carefully operated. In the field of organic synthesis, 4-tert-butoxy trifluorotoluene has a wide range of uses. Or can be used as an intermediate to prepare various organic materials with special properties, such as pharmaceuticals, pesticides and functional polymer materials. Due to its structure containing fluorine atoms, it has unique physical and chemical properties, good stability, and special solubility and reactivity. It has potential application value in many fields and can contribute to the development of organic synthesis.
Physical & Chemical Properties
4-Tert-butoxy trifluorotoluene has unique physical and chemical properties. Looking at its physical properties, it is often a colorless liquid with a specific taste. The boiling point is appropriate, and under normal temperature and pressure, it can maintain its liquid state, which is easy to store and transport. And its density is fixed, and when mixed with various substances, it is related to the mixed state.
On its chemical properties, the genus of tert-butoxy allows the substance to participate in various chemical reactions under specific conditions. The addition of trifluoromethyl increases its chemical stability and resists the invasion of many chemical reagents. The combination of the two makes 4-tert-butoxy trifluorotoluene unique in the field of organic synthesis, providing excellent raw materials for various reactions and producing a variety of organic products.
Technical Specifications & Labeling
There are chemical products today, called 4-tert-butoxy trifluorotoluene. Its process specifications and identification (product parameters) are the key.
In terms of process specifications, when preparing, it is necessary to accurately control the temperature, the ratio of raw materials must be in line with the law, and the reaction time during this period should not be slightly poor, so as to ensure its high quality. And the utensils used must be clean and dye-free to avoid impurities mixed in and damage its quality.
As for the identification (product parameters), the purity should be extremely high, and the impurity content should be minimal. Its physical properties, such as color, smell, melting point, boiling point, etc., are fixed and cannot be disturbed. On the packaging, its name should be clearly marked, with necessary warnings to inform everyone of its characteristics and attention, so that the user can understand it and use it correctly.
Preparation Method
The method of making 4-tert-butoxy-trifluorotoluene is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw materials are potassium tert-butoxide and trifluoromethylphenylboronic acid, which have suitable activities and can promote the smooth reaction. The production process is in an anhydrous environment protected by nitrogen, using tetrahydrofuran as a solvent to mix the raw materials in a certain proportion. First control the temperature to a low temperature, slowly stir to make the material evenly disperse, which is the key to the initiation of the reaction. In the reaction step, the temperature is gradually increased, triggering a nucleophilic substitution reaction between the two, and the tert-butoxy group is connected to the trifluoromethylphenylboronic acid. The catalytic mechanism uses copper salt as a catalyst to increase Copper ions coordinate with the reactants, optimize the distribution of electron clouds, and make the reaction proceed efficiently, thus 4-tert-butoxy trifluorotoluene can be obtained.
Chemical Reactions & Modifications
I am still trying to study the chemical and reverse modification of 4 Tert Butoxy Benzotrifluoride. This compound is used for its special properties, but its reverse properties are still unknown.
Its chemical and reverse properties often require specific components, such as the degree and catalysis. The method of the past may not be good, and the yield is not ideal. I am thinking of changing its reverse approach, and using new catalysis to increase its reverse efficiency.
It is also important to modify it. To make this compound have better properties, such as qualitative and solubility. Modified by the ancient method, the effect is not good. Start with the current molecular research, study its characteristics, and hope to make a breakthrough, so that this compound can be used more effectively in the field of engineering and scientific research, and achieve its greater value.
Synonyms & Product Names
4-tert-butoxy trifluorotoluene, which is very important in the chemical industry. Its aliases are many, or tert-butyl 4-trifluoromethyl phenyl ether, also known as 4- (tert-butoxy) trifluorotoluene.
In the records of various ancient books, although the names are different, they actually refer to the same thing. When traders trade, according to regional customs and industry practices, the names used are different, but it is clear that it refers to 4-tert-butoxy trifluorotoluene.
This substance is widely used in chemical synthesis and other things. It can be used as a raw material and an intermediate to help prepare various fine chemicals. Its various names are parallel, just like the old saying that "although the names are different, they are actually the same". Although the names are different, the entities referred to are consistent, adding to the chemical industry and promoting its development and evolution.
Safety & Operational Standards
4-tert-butoxy trifluorotoluene
Safety and operation specifications for 4-tert-butoxy trifluorotoluene
4-tert-butoxy trifluorotoluene is a commonly used raw material in chemical preparation. If you want to make good use of this material, you must first clarify its safety and operation specifications to ensure that everything goes smoothly and avoid disasters.
This material has certain chemical activity. In case of hot topic, open flame or strong oxidant, there is a risk of explosion. Therefore, when storing, it should be placed in a cool and ventilated warehouse, away from fire and heat sources, and stored separately from oxidants and acids. Do not mix storage. The lighting, ventilation and other facilities in the warehouse should be explosion-proof, and the switch should be placed outside the warehouse to prevent accidents.
When operating, make sure that the operator is professionally trained and strictly abide by the operating procedures. It is recommended that the operator wear a self-priming filter gas mask (half mask), wear chemical safety glasses, wear anti-poison penetration work clothes, and wear rubber oil-resistant gloves to prevent hazards. The operating environment should be well ventilated to avoid steam leakage into the air. When handling, it should be handled lightly to prevent damage to the packaging and containers.
If you accidentally come into contact with the skin, you should immediately take off the contaminated clothes, rinse with a large amount of flowing water for at least 15 minutes, and then seek medical attention. If it splashes into the eyes, you should immediately lift the eyelids, rinse thoroughly with a large amount of flowing water or normal saline for at least 15 minutes, and seek medical attention in time. If inhaled, should quickly leave the scene to fresh air, keep the respiratory tract unobstructed; such as breathing difficulties, give oxygen; if breathing stops, immediately perform artificial respiration and seek medical attention.
During emergency treatment, if there is a leak, the personnel in the leakage contaminated area should be quickly evacuated to the safe area, and quarantined, strictly restricting access. Cut off the source of fire. It is recommended that emergency personnel wear self-contained positive pressure breathing apparatus and wear anti-toxic clothing. Cut off the source of leakage as much as possible. Prevent it from flowing into restricted spaces such as sewers and drainage ditches. Small leakage: Absorb with sand, vermiculite or other inert materials. It can also be scrubbed with an emulsion made of non-flammable dispersant, diluted with the washing liquid and placed into the wastewater system. Large leakage: build a dike or dig a pit for containment. Cover with foam to reduce vapor hazards. Transfer to a tanker or special collector with an explosion-proof pump, recycle or transport to a waste treatment site for disposal.
In general, the use and storage of 4-tert-butoxy trifluorotoluene must comply with the above safety and operating standards to ensure personnel safety and environmental safety, so that chemical research and production can proceed smoothly.
Application Area
4-tert-butoxy trifluorotoluene has a wide range of application fields. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new special drugs for the well-being of patients. In the field of materials science, it can participate in the research and development of high-performance materials to improve the properties of materials such as stability and weather resistance. In the field of fine chemicals, this compound can be used to synthesize fine chemicals with special functions, such as high-end coatings, dyes, etc., giving products unique properties and quality. Therefore, 4-tert-butoxy trifluorotoluene has shown important value in many application fields and is of great significance to promote the progress and development of related industries.
Research & Development
Yu has been dedicated to the research of chemical substances for a long time, and recently focused on the research of 4-tert-butoxy trifluorotoluene. This substance has unique properties and has great potential in many fields.
Yu scrutinized its synthesis method, considered the selection of raw materials and reaction conditions, and strived to improve. After repeated experiments, improved the process, and hoped to improve the yield and purity.
Viewing its application prospects, it can be used in medicine, materials and other industries. In medicine, it may help the development of new drugs, and materials may be able to give materials special properties.
However, the road to research has many obstacles. The complexity of the reaction and the harsh conditions are all challenges. However, I adhere to the heart of research, not afraid of difficulties, and hope to make achievements in the research and development of 4-tert-butoxy trifluorotoluene, which will contribute to the field of chemistry and reach a new frontier.
Toxicity Research
In recent years, I have focused on the investigation of the toxicity of chemical substances, especially the substance 4-Tert-Butoxy Benzotrifluoride. This substance is increasingly used in the field of industry, but its toxicity has not been studied in detail.
I have checked the ancient books, looked at the data of its experiments, and observed the characteristics of its effect on organisms. In animal experiments, it may cause damage to organs and interfere with the normal order of physiology. At first contact, you can see the difference in behavior, and then the physiological function also seems to decay.
Also think about it in the environment, or through diffusion and migration, it affects the surrounding ecology. Aquatic things and terrestrial plants are all affected by it. Although the current evidence is not full of its harm, the potential danger cannot be ignored.
I will study diligently and obtain a complete and accurate conclusion. To show the true toxicity of 4-Tert-Butoxy Benzotrifluoride, provide a reliable lesson for the world when using this substance, and protect the ecological and personal safety.
Future Prospects
The 4 - Tert - Butoxy Benzotrifluoride is also used to transform things. Today's products have similar characteristics, and they are all useful in the field of engineering and scientific research.
Looking forward to the future, the scenery of its development can be looked forward to. Technology is new, and demand is also increasing. This product may be used in the research of new materials, and it can be used for general purpose. Such as the work of the child, the material is expected to have special properties, and the 4 - Tert - Butoxy Benzotrifluoride may be able to help it.
Furthermore, in the research and development, there are also its problems. Or it can be used in the middle of the research, to help the synthesis of the product, to improve its strength. In addition, 4 - Tert - Butoxy Benzotrifluoride is not yet developed, it is suitable for development, and it is beneficial to the world.
Where to Buy 4-(Tert-Butoxy)Benzotrifluoride in China?
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Frequently Asked Questions

As a leading 4-(Tert-Butoxy)Benzotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the main use of 4- (Tert-Butoxy) Benzotrifluoride?
4- (tert-butoxy) trifluorotoluene has a wide range of uses. In the field of organic synthesis, it is a key intermediate. In terms of the preparation of specific drugs, its structure can be cleverly modified through chemical reactions, incorporated into drug molecules, giving drugs unique pharmacological activities, which are of great benefit to the treatment of specific diseases.
In the field of materials science, 4- (tert-butoxy) trifluorotoluene also has important functions. After special processing, it can participate in the material synthesis process and improve material properties, such as enhancing material stability and enhancing chemical resistance, which contribute to the creation of high-performance new materials.
In the preparation of fine chemical products, it can be used as a raw material or additive to improve product quality and performance. If used in the production of special coatings, it can endow the coatings with excellent weather resistance and wear resistance, making them suitable for a variety of harsh environments.
In summary, 4 - (tert-butoxy) trifluorotoluene is an indispensable substance in many fields such as organic synthesis, materials science, and fine chemicals, promoting technological progress and product innovation in various fields.
What are the physical properties of 4- (Tert-Butoxy) Benzotrifluoride?
4- (tert-butoxy) trifluorotoluene is also an organic compound. Its physical properties are quite impressive.
Looking at its properties, under normal temperature and pressure, it often appears as a colorless to light yellow transparent liquid, which is convenient for it to participate in reactions in many chemical reaction systems. And because it is a liquid, it has good fluidity, which can make the contact between the reactants more sufficient and accelerate the reaction process.
As for the boiling point, it is within a certain numerical range. This boiling point characteristic determines the conditions required for separation, purification and other operations. If you want to separate this substance from the mixture, you need to apply the method of distillation according to its boiling point, control the appropriate temperature, so that 4 - (tert-butoxy) trifluorotoluene is gasified and then condensed to collect, so as to achieve the purpose of purification.
Melting point is also one of its important physical properties. Under specific low temperature conditions, this substance will change from liquid to solid. Knowing the melting point is of great significance during storage and transportation. It can be adjusted according to the ambient temperature to ensure that it maintains the required physical state and avoids changing its state due to improper temperature and affecting the quality.
Its density has a specific value compared to water. This density characteristic is very important in the operation of liquid-liquid separation. If the density of the liquid mixed with it is significantly different from it, the two can be separated by liquid separation method, and the delamination characteristics under the action of gravity can be used to achieve effective separation.
In terms of solubility, 4- (tert-butoxy) trifluorotoluene is soluble in some organic solvents, such as common aromatic hydrocarbons, halogenated hydrocarbons and other solvents. This solubility facilitates its use as a solvent or reactant in organic synthesis, allowing the reaction to proceed in a homogeneous system, which helps to improve the reaction rate and product purity.
In addition, its volatility is also reflected to a certain extent. Although it is not highly volatile, some molecules will still escape into the air under appropriate temperature and ventilation conditions. When handling this substance, it is necessary to pay attention to this characteristic and take ventilation protection measures to ensure the safety of operators and the cleanliness of the environment.
What are the chemical properties of 4- (Tert-Butoxy) Benzotrifluoride?
4 - (tert-butoxy) trifluorotoluene is also an organic compound. Its properties are both physical and chemical.
In terms of its physical properties, under room temperature and pressure, it is a colorless and transparent liquid with a light taste and no odor. Its boiling point is moderate, and it gasifies at a certain temperature, which can be used for separation and purification. Its density is lighter than that of water, and it is insoluble in water, but it is miscible with common organic solvents such as ethanol, ether, and dichloromethane. Due to the similar principle of compatibility, its molecular structure is similar to that of organic solvents.
As for chemical properties, because it contains trifluoromethyl, it has strong electronegativity, which makes the molecule have a certain polarity, which affects its reactivity. The tert-butoxy group is the power supply group. Although the steric barrier is large, it is useful in specific reactions. It can participate in nucleophilic substitution reactions. Because the electron cloud density of the benzene ring is affected by the substituent group, the nucleophilic reagent can attack the specific position of the benzene ring. Under appropriate conditions, the ether bond cleavage reaction occurs, which may cause the tert-butoxy group to leave due to the acidic or basic environment, and then form new compounds. And in oxidation and reduction reactions, depending on the reaction conditions, there are different transformations, which may increase the number of organic synthesis paths. In organic synthesis in the fields of medicine, pesticides, materials, etc., it is often used as a key intermediate to form products with special properties.
What are the synthesis methods of 4- (Tert-Butoxy) Benzotrifluoride?
To prepare 4 - (tert-butoxy) trifluorotoluene, the following numbers are often followed.
First, 4-hydroxytrifluorotoluene is reacted with tert-butanol under the action of an appropriate catalyst. 4-hydroxytrifluorotoluene has an active hydroxyl group, and the hydroxyl group of tert-butanol can be substituted with it. This reaction requires the selection of a suitable catalyst, such as concentrated sulfuric acid or a specific Lewis acid. Concentrated sulfuric acid can promote protonation, making the hydroxyl group of tert-butanol easy to leave, and the phenoxy negative ion of 4-hydroxytrifluorotoluene attacks the nucleophilic, and then becomes the target product. However, concentrated sulfuric acid is highly corrosive, and the operation needs to be cautious. The reaction conditions are harsh, and the temperature and time need to be controlled accurately. Otherwise, side reactions will occur and
Second, 4-halogenated trifluorotoluene reacts with potassium tert-butoxide. The halogen atom in 4-halogenated trifluorotoluene has high activity, and potassium tert-butoxide has strong alkalinity and nucleophilicity. The oxygen anion of potassium tert-butoxide nucleophilically attacks the alpha-carbon of the halogen, and the halogen ion leaves to form 4- (tert-butoxy) trifluorotoluene. This reaction condition is relatively mild and the yield is high. However, potassium tert-butoxide needs to be prepared and used now, because it is sensitive to water and air and inconvenient to store.
Third, 4-nitrotrifluorotoluene is used as the starting material. It is first reduced to 4-aminotrifluorotoluene, and then diazotized and hydrolyzed to obtain 4-hydroxytrifluorotoluene, and then reacted with tert-butanol according to the first method. This route step is complicated, but the raw material is easy to obtain. When reducing 4-nitrotrifluorotoluene, hydrogen-palladium carbon or iron-hydrochloric acid systems can be selected. The diazotization reaction needs to be low temperature to maintain the stability of the diazonium salt, and the conditions for hydrolysis need to be carefully regulated.
All these production methods have advantages and disadvantages. In actual synthesis, the choice is based on factors such as raw material availability, cost, yield and purity.
What is the price range of 4- (Tert-Butoxy) Benzotrifluoride in the market?
4 - (tert-butoxy) trifluorotoluene, the value of the market is difficult to determine. The change in its price is affected by various factors.
First, the state of supply and demand is the key. If there are many people in the market, but the supply is small, the price will tend to rise; conversely, if the supply exceeds the demand, the price will drop.
Second, the cost of production is also a factor. The price of raw materials, the cost of labor, and the consumption of equipment are all related to the production. If the price of raw materials is high, or the cost of labor and equipment increases, the price will also rise.
Third, the competition in the market has a great impact.
Fourth, the regulations of government decrees cannot be ignored. Changes in taxes and different regulations can make prices different. Taxes increase in weight, and prices may rise as a result; loose regulations may have the effect of reducing costs and promoting prices.

Looking at the past, the price of such chemicals in the market fluctuated every time. However, the price of 4 - (tert-butoxy) trifluorotoluene is now between hundreds and thousands of yuan per kilogram or per kilogram. If you want to know the exact number, you should consult the commercial of chemical materials or observe the real-time reports in the market.