4-Nitrobenzotrifluoride

Specifications

HS Code	959267
Chemical Formula	C7H4F3NO2
Molar Mass	191.107 g/mol
Appearance	Colorless to light yellow liquid
Odor	Pungent odor
Density	1.38 g/cm³
Boiling Point	202 - 204 °C
Melting Point	-3 °C
Solubility In Water	Insoluble
Vapor Pressure	0.17 mmHg at 25 °C
Flash Point	88 °C
Refractive Index	1.475 - 1.477

As an accredited 4-Nitrobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	500 - gram bottle packaging for 4 - Nitrobenzotrifluoride chemical.
Storage	4 - Nitrobenzotrifluoride should be stored in a cool, well - ventilated area, away from heat and ignition sources. Keep it in a tightly closed container made of suitable materials, like steel or high - density polyethylene, to prevent leakage. Store separately from incompatible substances such as oxidizing agents and reducing agents to avoid potential reactions.
Shipping	4 - Nitrobenzotrifluoride is a hazardous chemical. Shipping requires proper packaging in accordance with regulations. It must be labeled clearly, transported by approved carriers, ensuring safety during transit.

Free Quote

Competitive 4-Nitrobenzotrifluoride prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615380400285 or mail to sales2@boxa-chemical.com.

We will respond to you as soon as possible.

Tel: +8615380400285

Email: sales2@boxa-chemical.com

General Information

Historical Development

The industry of chemical industry is changing with each passing day, and there are names 4-Nitrobenzotrifluoride. It is quite important in the field of chemical industry today. Tracing its origin, scholars at the beginning studied it and dedicated themselves to the exploration of new things. After several years, something has been achieved. At the time of initial production, the process was complicated and the production efficiency was not abundant. However, the sages worked tirelessly, refined research and improvement, and the process gradually matured.
In the past, everyone groped in the dark, and with perseverance, they broke through many obstacles. Looking at this now, it is very useful in the fields of medicine and materials. From the beginning of little known to today, it is widely used, which is really the progress of the history of chemical industry. Its development also gathers the efforts of scholars, paves the way for the development of chemical industry in later generations, and is also a model for our generation to study.

Product Overview

4-Nitrotrifluoromethylbenzene is an important chemical in organic synthesis. Its properties are colorless to light yellow liquid with a special odor. The boiling point is quite suitable, and it is easy to control during chemical operation.
This compound plays a significant role in the field of organic synthesis. It is often a key intermediate for the preparation of many drugs, pesticides and functional materials. Because it contains nitro and trifluoromethyl functional groups, it endows the molecule with unique chemical properties and can participate in a variety of organic reactions, such as nucleophilic substitution, reduction, etc.
This compound can be obtained through a specific synthesis path with precise reaction conditions and raw material ratios. In industrial production, focus on optimizing processes to increase productivity, reduce costs, and ensure safe production. Its wide application provides assistance for the development of the chemical industry and promotes continuous progress in related fields.

Physical & Chemical Properties

4-Nitrobenzotrifluoride is an organic compound. Its physical and chemical properties are unique and worthy of study. This substance is mostly liquid at room temperature, and its color is nearly transparent. Its boiling point is quite high, reaching about 200 degrees. This property makes it a stable solvent in specific high temperature reaction systems.
Looking at its chemical properties, it has strong electron absorption due to its nitro and trifluoromethyl groups. Nitro reduces the electron cloud density of the benzene ring, causing its electrophilic substitution activity to decrease, and the reaction check point is mostly in the meso. The existence of trifluoromethyl enhances molecular stability and fat solubility, making it special for specific organic synthesis reactions. And because of its stable chemical structure, it is not easy to decompose under common conditions, providing a stable reaction substrate for many chemical processes. The characteristics of its physical and chemical properties make it play an important role in the fields of medicine and material synthesis.

Technical Specifications & Labeling

There is a way to make 4-Nitrobenzotrifluoride, and its technical regulations and identification (product parameters) are the key. To make this product, when the quality and quantity of the raw materials are known in advance, they should be prepared according to the exact method. When reacting, control the temperature at an appropriate degree, observe its changes, abide by the rules, and do not make mistakes.
After making it, check its quality in detail, observe the color and smell, and measure its purity, boiling point and other parameters. When the color is pure, the taste is not different, the purity must reach a specific standard, and the boiling point is also in line with the specified value. This is the label of the product, which is related to its use. According to this technical regulations and identification, the product of 4-Nitrobenzotrifluoride can be of good quality to meet all needs.

Preparation Method

4-Nitro-tris, fluoromethylbenzene, is an important product in the chemical industry. Its preparation method is related to the raw materials and production, technology, reaction steps, catalytic mechanism, and is very important.
Preparation, this product is often made of tris, fluoromethylbenzene, supplemented by nitrifying reagents. In a suitable reaction vessel, control the temperature and pressure of the strips. First, the reactants are uniformly mixed, and then gradually heated to promote the reaction with a catalyst.
In the reaction step, the nitrifying reagent reacts with tris, fluorine, methyl, and benzene, via electrophilic substitution, mechanism, nitro entry, benzene ring, at a specific position, to obtain 4-nitro tris, fluorine, methyl, benzene. To be reacted, completed, separated, purified, processed, removed, heterogeneous, obtained, pure, square, obtained, product, preparation.

Chemical Reactions & Modifications

The chemical reaction and modification of 4-nitrotrifluorotoluene are crucial to the study of chemical substances. The reaction of this compound requires precise consideration of its characteristics.
In many chemical experiments, 4-nitrotrifluorotoluene exhibits a unique reaction path. The presence of its nitro group and trifluoromethyl gives it special chemical activity. With appropriate modification, its properties may be optimized.
To improve this compound, consider the regulation of reaction conditions. Temperature and catalyst can influence the reaction direction. Reasonable selection of catalyst may accelerate the reaction rate and obtain better products.
Or adjusting the pH of the reaction environment is also a good strategy for modification. Precise control of these elements may enable 4-nitrotrifluorotoluene to exhibit better chemical properties and be more widely used in the chemical industry.

Synonyms & Product Names

Today there is a thing called 4 - Nitrobenzotrifluoride. The synonyms and trade names of this thing are related to the importance of our research.
4 - Nitrobenzotrifluoride, its synonyms have various expressions. Or according to its chemical properties, it is called by another name, but they all refer to the same thing. As for the trade name, it is also called by different names in market transactions and industrial applications.
Looking at its synonyms, chemists call each other in professional terms, and according to its molecular structure and chemical properties, it is given a precise name, which is different from other things. And the trade name is designed to facilitate market circulation and commercial promotion. In order to make this object more recognizable and acceptable to the public, merchants took the name of popular and easy to remember.
Explore the synonyms and trade names of 4-Nitrobenzotrifluoride, which are of great significance in chemical research, industrial production and commercial transactions. It can enable all parties, whether scholars, craftsmen or merchants, to understand the things referred to by their familiar names, so as to travel freely in academic research, manufacturing applications, and transactions without confusion.

Safety & Operational Standards

4-Nitrotrifluorotoluene is also a chemical product. In the process of production, safety and regulations are of paramount importance.
If you want to make this thing, all kinds of raw materials and equipment should be carefully selected. The raw materials must be pure, and the equipment must be good to prevent impurities, damage, and danger to the work.
During the work, the temperature and pressure limits should be observed. 4-Nitrotrifluorotoluene is made. It is easy to promote reaction at high temperature, and then it will explode if it passes. Therefore, the temperature should be controlled in a suitable area, and with precise equipment, it can be constantly monitored and adjusted. The same is true for pressure. If it is too high or too low, it will be harmful to the production, or cause danger.
For workers, protective gear is indispensable. Clothes are made to resist chemicals, which can isolate poison and corrosion; masks can filter air and keep breathing clean; gloves are firm and durable, and the palms are safe.
When storing and transporting, there are also rules to follow. The storage place should be cool and dry, protected from fire and heat, to prevent ignition and explosion. The transportation is stable and careful, preventing collision and shaking, avoiding damage to packaging and leaking.
The principle of waste should not be ignored. 4 - The waste of nitrotrifluorotoluene, whether poisoned or corroded, should not be discarded. It must be handled according to the law, turning harm into profit, or discarding it without harming, and protecting the safety of the ring.
In short, the production of 4-nitrotrifluorotoluene, from beginning to end, safety and regulations are the top priority. Only by observing it can we ensure the smooth production, the safety of people, and the peace of the environment.

Application Area

4 - Nitrobenzotrifluoride, it is also a chemical thing. Its application is not limited. In the field of technology, it can be used to synthesize raw materials for multi-special effects, to help people heal. In the field of technology, it can be used to develop high-efficiency and low-toxicity products, to protect crops from damage and protect crops. In the field of materials, this compound can be used as a high-performance material, so that the material has special properties, such as better corrosion resistance, mechanical properties, etc. In general, 4 - Nitrobenzotrifluoride has its indispensable role in many aspects, and promotes the development of various industries.

Research & Development

In recent years, I have focused on the research of 4-Nitrobenzotrifluoride. This material is unique, has a wide range of uses, and has potential in the fields of medicine and pesticides.
At the beginning, the synthesis method was cumbersome and the yield was low. My colleagues and I worked hard, checked the classics, and improved the process after months of testing. Under the new technique, the yield gradually increased and the quality was also excellent.
However, the research does not stop there. In order to make this product more widely used, we explore its reaction characteristics with other substances, hoping to open up new paths. Although we have achieved something today, the road ahead is still far away. We must make unremitting research, hoping that this product will shine in the future and contribute to the development of the industry.

Toxicity Research

Since modern times, chemical refinement, all kinds of compounds have emerged. Today there are 4-Nitrobenzotrifluoride of this substance, and the study of its toxicity is the most important.
In the laboratory, observe its properties, smell its smell, observe its response to other substances, to judge its nature. After several trials, you can know what signs of toxicity it has.
Or cloud, this substance enters the body, it may damage the organs and disrupt the luck of qi and blood. If the skin touches it, it may also be sick. However, it may be useful in industry, so it should not be discarded for fear of its poison.
It is necessary to study the degree of toxicity and explore the method of protection to ensure the safety of workers, and the use of this product can also benefit the world without harm. Detailed investigation of its toxicity mechanism is the right way to prepare for it.

Future Prospects

The future outlook concerns 4 - Nitrobenzotrifluoride products, which are important in the chemical industry. Although its application has a certain extent at present, there is still a broad field of expansion in the future.
From the perspective of synthesis, in the future, more subtle, efficient and green ways may be found, making the preparation process simpler, reducing energy consumption, and minimizing the impact on the environment. As for the application level, in materials science, it is expected to give birth to new substances with outstanding performance, which will shine in the fields of electronic devices, aerospace materials, etc. In pharmaceutical research and development, it may become a key intermediate to help create new drugs with special effects and cure more diseases.
Over time, with the unremitting advancement of scientific research, 4-Nitrobenzotrifluoride will surely be able to shine like a star, radiate brilliant light in many fields, and contribute extraordinary power to the progress and well-being of mankind.

Where to Buy 4-Nitrobenzotrifluoride in China?

As a trusted 4-Nitrobenzotrifluoride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 4-Nitrobenzotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-Nitrobenzotrifluoride?

4-Nitrobenzotrifluoride, or 4-nitrotrifluorotoluene, is a crucial raw material in the field of organic synthesis. It has a wide range of uses and plays a key role in many industries.
First, in the field of pharmaceutical chemistry, this substance can be used as an important intermediate. Take the synthesis of specific drug molecules as an example, because of its unique chemical structure, it can participate in the construction of key parts of drug molecules. With the characteristics of benzene ring, nitro group and trifluoromethyl group, it can endow drugs with specific physiological activities and pharmacological properties, such as improving the lipid solubility of drug molecules, making it easier to penetrate biofilms, thereby improving drug absorption efficiency and bioavailability.
Second, in the synthesis of pesticides, 4-nitrotrifluorotoluene is also indispensable. It can be used to create new pesticides and use its structural characteristics to enhance the effect of pesticides on specific pests or pathogens. For example, its structure can affect the binding ability of pesticides to specific targets in pests or pathogens, enhance the insecticidal and bactericidal activities of pesticides, and the introduction of trifluoromethyl can improve the stability and environmental adaptability of pesticides.
Third, in the field of materials science, this compound can be used as a starting material for the synthesis of special functional materials. When preparing some polymer materials with special optical and electrical properties, 4-nitrotrifluorotoluene is introduced into the polymer main chain or side chain through a specific chemical reaction, which can endow the material with unique properties. If the photoelectric conversion efficiency of the material is improved, it has potential application value in the field of organic optoelectronic materials.
Furthermore, in the dye industry, 4-nitrotrifluorotoluene can participate in the synthesis of new dyes. Due to the presence of nitro and trifluoromethyl groups on the benzene ring, the conjugate structure and electron cloud distribution of dye molecules can be adjusted, and then the color and color fastness of dyes can be changed, providing the possibility for the development of high-performance and novel color dyes.

What are the physical properties of 4-Nitrobenzotrifluoride?

4-Nitrotrifluorotoluene is an important compound in organic chemistry. Its physical properties are particularly crucial and are related to many practical applications.
This compound is in a colorless to light yellow liquid state, which is quite characteristic. Its pungent smell and strong stimulation of the ability to smell warn people to pay more attention when operating.
The boiling point is 202-204 ° C. At this temperature, the substance changes from liquid to gaseous state. This boiling point characteristic is of great significance in the process of separation and purification. It can be separated from the mixture by distillation and other means according to the difference in boiling points.
The melting point is about -3 ° C. At low temperature, it will solidify from liquid to solid state. Melting point knowledge helps to control its phase changes, providing a key basis for setting storage and transportation conditions.
The relative density is 1.47 (water = 1), which means that under the same volume, its mass is heavier than water. This property affects its distribution in solution and is an important consideration during extraction and other operations.
Its solubility is also an important property. 4-Nitrotrifluorotoluene is insoluble in water, but soluble in most organic solvents, such as ethanol, ether, etc. This difference in solubility provides an effective way to extract and separate it from the impurity-containing system by organic solvents during organic synthesis and separation.
Vapor pressure is related to its volatility, and at a certain temperature, there will be a corresponding vapor pressure. This parameter is closely related to environmental factors and storage conditions, and is of great significance for understanding its diffusion and storage stability in the environment.
The physical properties of 4-nitrotrifluorotoluene lay a solid foundation for its application in chemical industry, medicine and other fields. It needs to be carefully considered in production and operation.

What is the chemistry of 4-Nitrobenzotrifluoride?

4-Nitrotrifluorotoluene has unique chemical properties and is quite interesting to explore. This substance has strong chemical activity due to the presence of nitro and trifluoromethyl groups. Nitro groups are strong electron-absorbing groups, which reduce the electron cloud density of the benzene ring, make the benzene ring more susceptible to attack by nucleophiles, and make the adjacent and para-position electron cloud density drop even more, so nucleophilic substitution reactions mostly occur in the meso-position. For example, when reacted with nucleophiles such as alkoxides and amines, new nitrogen-containing or oxygen-containing derivatives can be formed. This reaction is widely used in organic synthesis and can be used to prepare intermediates for a variety of drugs and pesticides.
Trifluoromethyl is also a strong electron-absorbing group, with high electronegativity and small steric resistance. Its existence increases the polarity of molecules and affects the physical and chemical properties of substances. Due to the strong electron-absorbing effect of trifluoromethyl, the acidity of 4-nitrotrifluorotoluene is enhanced compared with toluene. The presence of trifluoromethyl enhances the stability and chemical inertness of the substance, making it a stable structural unit in some chemical reactions.
4-nitrotrifluorotoluene may participate in free radical reactions under light or heating conditions. The presence of nitro can cause molecules to generate free radicals under specific conditions, which can then initiate a series of free radical chain reactions. This is another way for it to participate in organic synthesis reactions. It can also undergo a reduction reaction, and the nitro group can be reduced to an amino group to form 4-aminotrifluorotoluene. This product is an important organic synthesis intermediate and is widely used in the production of dyes, medicine and other fields.
In the field of organic synthesis, 4-nitrotrifluorotoluene provides an important starting material and structural module for the synthesis of complex organic compounds due to its unique chemical properties, and plays a key role in the construction of new organic molecular structures and the development of new drugs and materials.

What are the preparation methods of 4-Nitrobenzotrifluoride?

The preparation method of 4-nitrotrifluorotoluene has been known in ancient times. In the past, this compound was prepared by the following methods.
First, trifluorotoluene was used as the starting material and prepared by nitrification reaction. The trifluorotoluene was placed in a suitable reaction vessel and slowly mixed acid (mixture of sulfuric acid and nitric acid) was added dropwise under low temperature conditions. This process requires strict control of the reaction temperature and dropwise speed to prevent side reactions from occurring. In this reaction, sulfuric acid not only provides an acidic environment for the reaction, but also promotes the production of nitroyl cation (NO ²) from nitric acid, which is the key active intermediate in the nitrification reaction. The benzene ring of trifluorotoluene is affected by trifluoromethyl, and the electron cloud density decreases, so the reaction conditions are more severe than that of ordinary aromatic hydrocarbons. After the reaction, 4-nitrotrifluorotoluene can be obtained by washing with water, alkali washing, drying and other post-processing steps.
Second, p-nitrobenzoic acid is used as raw material and prepared by fluorination reaction. First, the p-nitrobenzoic acid is converted into the corresponding acid chloride, and the commonly used chlorination reagent such as dichlorosulfoxide. Subsequently, the acid chloride is reacted with fluorinated reagents (such as hydrogen fluoride pyridine salt, etc.) to achieve the substitution of fluorine atoms to chlorine atoms, and then 4-nitrotrifluorotoluene is generated. This route requires attention to the selection of fluorination reagents and the control of reaction conditions to ensure the selectivity and yield of the reaction.
Third, it is prepared by the nucleophilic substitution reaction of halogenated aromatics. Using p-chloronitrobenzene as the substrate, it reacts with trifluoromethylating reagents (such as trifluoromethyl copper lithium reagent, etc.). This reaction involves the attack of nucleophilic reagents on chlorine atoms in the aromatic ring to form carbon-fluorine bonds. However, such reactions need to be carried out under strict conditions of anhydrous and oxygen-free, and the reagents used are relatively special, which requires high reaction equipment and operation.
The above preparation methods have their own advantages and disadvantages, and they need to be selected according to actual needs and conditions in order to achieve the purpose of efficient preparation of 4-nitrotrifluorotoluene.

4-Nitrobenzotrifluoride What are the precautions during storage and transportation?

4-Nitrotrifluorotoluene is a chemical substance, and many things must be paid attention to when storing and transporting.
Its properties are harmful. When storing, it is advisable to find a cool, dry and well-ventilated place. Do not approach fire and heat sources to avoid the risk of fire and explosion. Because of its flammability, it is easy to cause danger in case of open flames and hot topics. It must be stored in isolation from oxidizing agents, reducing agents, alkalis, etc., because it is mixed with them, it may cause chemical reactions and cause accidents. And the storage place should have suitable materials to contain leaks.
As for transportation, the transportation vehicle must comply with the specifications for the transportation of dangerous chemicals. Transport personnel should be professionally trained and familiar with their characteristics and emergency response methods. During transportation, it should be ensured that the container does not leak, collapse, fall or damage. To prevent exposure to the sun, rain and high temperature. If it is road transportation, follow the prescribed route and do not stop in residential areas and densely populated areas. When rail transportation, it should also follow the relevant regulations and be properly equipped to prevent accidents. In this way, the safety of storage and transportation can be guaranteed, so as to avoid disasters.