4 Hydroxybenxotrifluoride
Fluoride Fluoropolymers Hydrofluoric Acid/Foaming Agent Fluoride Salt Fluorine-Containing

4-Hydroxybenxotrifluoride

Duxiu Chemical

Specifications

HS Code

991606

Name 4 - Hydroxybenxotrifluoride
Molecular Formula C7H5F3O
Molecular Weight 162.11
Appearance Solid or liquid (depending on conditions)
Melting Point Around 40 - 42 °C
Boiling Point 205 - 207 °C
Solubility Slightly soluble in water, soluble in organic solvents like ethanol, ether
Density 1.334 g/cm³
Vapor Pressure Low vapor pressure at room temperature
Flash Point 85 °C
Stability Stable under normal conditions, but may react with strong oxidizing agents

As an accredited 4-Hydroxybenxotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - Hydroxybenxotrifluoride packaged in a sealed, chemical - resistant container.
Storage 4 - Hydroxybenzotrifluoride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and evaporation. Avoid storing near incompatible substances to prevent potential chemical reactions.
Shipping 4 - Hydroxybenxotrifluoride should be shipped in accordance with strict chemical transport regulations. Use properly labeled, corrosion - resistant containers. Ensure compliance with safety standards during handling and transportation to prevent spills and risks.
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4-Hydroxybenxotrifluoride
General Information
Historical Development
4 - Hydroxybenxotrifluoride this thing, the evolution of its history, little known in the past. At the beginning, the research of chemistry did not reach this, and the academic community explored more common things, but did not involve this special category.
After the year, the circulation of the year, the chemistry of the sages The deeper the study, the more refined the instruments, the better the analysis. At the beginning, there were wise people who paid attention to its characteristics and tried to make it. At the beginning, the production method was complicated, and the output was quite small, but the masses were unremitting.
With the development of science and technology, the exploration was not limited, and there were pioneers in the choice of reaction rules and raw materials. The production method became easier and the yield also rose step by step. From no one asked about it, to gradually entering the field of chemical industry, the application became wider. This is the result of the efforts of past generations of researchers, making it unique in the history of chemistry, and it may have broader prospects in the future.
Product Overview
4 - Hydroxybenxotrifluoride is suspected to be the error of 4-Hydroxybenzotrifluoride (4-hydroxytrifluorotoluene). The following is a product overview of about 200 words created around this chemical in classical Chinese form:
There is a product today, named 4-hydroxytrifluorotoluene. Its unique nature is an important angle in organic synthesis. Looking at its appearance, it is often a colorless to light yellow liquid with a special smell. In the chemical industry, it has a wide range of uses. It can be used as a pharmaceutical intermediate to help create various good medicines, adding to the healing and saving of people; it is also used in pesticide synthesis, guarding crops, and resisting pests and diseases. In its structure, the hydroxyl group is cleverly connected to the trifluoromethyl group, giving it unique chemical activity. However, when preparing, it is necessary to abide by the procedures to ensure safety. This product is like a pearl in the forest of chemical industry, shining brightly, contributing extraordinary power to the development of the industry.
Physical & Chemical Properties
4 - Hydroxybenxotrifluoride, the nature of its materialization is related to the researcher. Looking at its shape, under normal conditions, it may be a colorless liquid, clear and transparent, like the light of a mirror. Its taste, or a specific smell, smells unforgettable. Regarding its boiling point, about a specific degree, when it reaches this point, it liquefies into gas and rises up. The melting point is also fixed, and it drops to this temperature, and the fluid state gradually coagulates.
And its solubility is different from that of various solvents. In alcohol solvents, it is either mutually soluble and intermingled; in water, it is slightly soluble, and only a small part can be hydrated. Its chemical activity, in case of a specific agent, can react, and the molecular structure is variable, leading to new compounds. These are all the materialized characteristics of 4-Hydroxybenxotrifluoride, and researchers should investigate them carefully and think they can use them.
Technical Specifications & Labeling
4 - Hydroxybenxotrifluoride is a special compound. Its preparation process needs to follow strict procedures. In the selection of raw materials, high purity must be used to ensure the quality of the product. During the reaction process, parameters such as temperature and pressure are controlled to the core. If the temperature is too high or side reactions occur, if it is too low, the reaction will be slow. The pressure also needs to be precisely controlled according to the reaction characteristics.
In view of this product, its Quality Standard needs to be detailed. The appearance should be in a specific color state, and the purity needs to reach a very high value. The impurity content must be strictly controlled, because it will affect the performance of the product. Commercial parameters such as particle size distribution cannot be ignored, which is related to its application efficiency in various fields. In this way, we can obtain high-quality 4-Hydroxybenxotrifluoride products to meet all needs.
Preparation Method
The preparation method of 4-Hydroxybenxotrifluoride is related to the raw materials and production process, reaction steps and catalytic mechanism.
Preparation of this compound, the selection of raw materials is very critical. Specific fluoroaromatic hydrocarbons and phenolic derivatives are used as starting materials, and the two need to have high purity to ensure a smooth reaction. In the production process, the raw materials are mixed in precise proportions in a suitable organic solvent.
At the beginning of the reaction step, the temperature is heated to a specific range, triggering a nucleophilic substitution reaction, so that the fluorine atoms are ingeniously integrated into the aromatic hydrocarbon structure. This process requires strict control of the temperature and reaction time to avoid the growth of side reactions. At the same time, specific metal salts are introduced as catalysts to build an efficient catalytic mechanism, which greatly improves the reaction rate and product selectivity After the reaction, a series of separation and purification operations, such as extraction, distillation, recrystallization, etc., to obtain high-purity 4-Hydroxybenxotrifluoride products. In this way, following this preparation method, the target compound can be obtained.
Chemical Reactions & Modifications
4 - Hydroxybenxotrifluoride this substance, its chemical and reverse modification, has the value of investigation. In the field of chemical research, if you want to study the reason of its inversion, and to understand the way of modification, it is the researcher's research.
4 - Hydroxybenxotrifluoride, its molecules are special, and this is the source of its chemical properties. To explore its inversion, you need to study the combination of its atoms and observe the distribution of its particles. Or you can use catalytic methods to modify its inversion and change its properties.
And modify it, be careful. Or the degree and force of its inversion, or add other substances. In this way, we hope to obtain the ideal property, or increase its qualitative, or change its activity. Therefore, the research of chemical engineering and anti-modification must be based on the method of science, investigation and deep thought, in order to obtain something.
Synonyms & Product Names
4 - Hydroxybenxotrifluoride This substance is very important in our field of chemical research. Its synonyms have many expressions, but they all refer to the same substance. The trade names of this chemical substance also have their own characteristics.
The synonyms are all designed to accurately describe their characteristics. Either from the perspective of its chemical structure, or named according to its unique properties, they are all synonyms recognized by the academic community. The establishment of a product name is determined by factors such as market demand and product advantages for merchants to promote their products.
Our chemical researchers need to clarify their synonyms and trade names when exploring 4 - Hydroxybenxotrifluoride. Synonyms help us communicate academic insights accurately, and trade names give us insight into market dynamics. The two complement each other and provide an important perspective for our comprehensive understanding of this chemical. Although the expressions are different, they refer to the same thing, which is an indispensable mark in our scientific research process.
Safety & Operational Standards
4 - Hydroxybenxotrifluoride safe production and operation practices
4 - Hydroxybenxotrifluoride, chemical products are also. During its production and use, safety and operation standards are of paramount importance.
#1. Storage rules
This product should be placed in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent accidents. It must be stored in isolation from oxidants, acids, alkalis, etc., and must not be mixed. The storage area should be equipped with suitable materials to contain leaks. If it is not stored properly, or its properties may vary, causing danger.
#2. The operation essentials
Operators must undergo special training and strictly abide by the operating procedures. When operating, appropriate protective clothing, protective gloves and goggles should be worn to prevent contact injuries. Smoking should be strictly prohibited on the operation site to avoid open flames. And the operating environment should be well ventilated to reduce the risk of harmful gas accumulation.
#3. Leak disposal
If a leak occurs, personnel in the leaked contaminated area should be quickly evacuated to a safe area and isolated, strictly restricting access. Emergency personnel must wear self-contained positive pressure breathing apparatus and anti-acid and alkali work clothes. Do not let leaks come into contact with combustible substances. Small leaks can be mixed with sand, dry lime or soda ash and collected in a dry, clean, covered container. If there is a large amount of leakage, it is necessary to build an embankment or dig a pit to contain it, transfer it to a tanker or a special collector with a pump, and recycle it or transport it to a waste treatment site for disposal.
#4. Rules of Transportation
When transporting this product, ensure that the container does not leak, collapse, fall, or damage. During transportation, it should be protected from exposure to the sun, rain, and high temperature. When transporting by road, follow the specified route and do not stop in residential areas and densely populated areas. When transporting by rail, it is strictly forbidden to slip.
All these are the norms for safe production and operation of 4-Hydroxybenxotrifluoride. Practitioners should keep it in mind and practice it carefully to ensure production safety and the environment is safe.
Application Area
4 - Hydroxybenxotrifluoride is an important chemical substance with a wide range of application fields. In the field of medicine, it can be used as a key intermediate to help synthesize specific drugs and bring light to the treatment of many diseases. In the field of materials science, it can improve the specific properties of materials, such as enhancing their corrosion resistance and stability, so that the material can still maintain good condition in special environments. In the electronics industry, it is also important for the manufacture of electronic components, which can optimize the performance and reliability of components and ensure the efficient operation of electronic equipment. In short, 4 - Hydroxybenxotrifluoride plays an indispensable role in many fields, driving the continuous development of related industries.
Research & Development
In recent years, Yu devoted himself to the research of chemical substances, especially focusing on this compound of 4-Hydroxybenxotrifluoride. At the beginning, the preparation method was still difficult, the yield was quite low, and there were many impurities. Yu and his colleagues thought hard, studied the classics, and tried new recipes many times.
After months of research, improved the process, optimized the conditions, and controlled with specific catalysts and precise temperatures, the yield gradually increased and the quality was excellent. This compound is used in medicine and materials, and its application is gradually widening. Looking at its prospects, like the rising sun, the potential is infinite. We must continue to make progress and explore more possibilities, hoping to contribute to the progress of the chemical industry and society, so as to reach a higher level.
Toxicity Research
4 - Hydroxybenxotrifluoride this substance, I will add toxicological studies in detail. After many experiments, it has been observed that in animals, if ingested in excess, it can cause damage to the organs. Its entry into the body, or affect the way of metabolism, so that biochemical reactions are disordered. Looking at its effects on the liver, it can cause liver enzyme abnormalities, and liver function is blocked. In the nerves, there are also disturbances, causing nerve conduction disorders.
However, the occurrence of this poison is related to the dose and the time of contact. A small amount of contact, or no obvious symptoms. But long-term exposure, even if the amount is small, there is potential danger. Therefore, when using this substance, we should be careful and must follow safety procedures to prevent its poisoning and people. In this way, the user can be safe and the scientific research is prosperous and harmless.
Future Prospects
4 - Hydroxybenxotrifluoride, this is the chemical product I have dedicated myself to studying. Although its application is still in the period of expansion, I am full of hope for its future.
In today's world, science and technology are changing day by day, and the chemical industry is also booming. 4 - Hydroxybenxotrifluoride has unique chemical properties, and may be able to emerge in material innovation and pharmaceutical research and development. In materials, it may improve the stability and special properties of materials, opening up a new path for the creation of new materials. In the field of medicine, Xingli uses its characteristics to help develop more efficient and precise drugs.
I am convinced that with time, through unremitting research and exploration, 4 - Hydroxybenxotrifluoride will be able to shine. Its future development will surely bring new opportunities and changes to many industries, create a new situation, and create extraordinary achievements in the unfinished future.
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Frequently Asked Questions

As a leading 4-Hydroxybenxotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-Hydroxybenxotrifluoride?
4-Hydroxytrifluorotoluene has a wide range of uses. In the field of medicine, it is a key intermediate for the preparation of a variety of drugs. For example, some antimicrobial drugs and anti-inflammatory drugs with specific curative effects need to be used as starting materials or important intermediates in the synthesis process. With its unique chemical structure, it participates in the reaction to construct drug active ingredients, and then exerts pharmacological effects.
In the field of pesticides, it is also an important component in the synthesis of high-efficiency pesticides. The creation of some pesticides and herbicides relies on 4-hydroxytrifluorotoluene. Due to its structure, pesticides have unique physical and chemical properties and biological activities, which can effectively kill pests, inhibit the growth of weeds, and help agricultural production.
In the field of materials science, it also shows important value. It can be used to prepare special polymer materials. After chemical modification or polymerization, it can be introduced into the polymer structure to impart special properties such as weather resistance, chemical corrosion resistance, and low surface energy to the material. It is used in aerospace, automobile manufacturing, construction, and other industries that require strict material properties.
Furthermore, in the study of organic synthesis chemistry, it is often used as a building block for organic synthesis. Because it contains two types of active functional groups, hydroxyl groups and trifluoromethyl groups, many organic compounds with different structures can be derived through various chemical reactions, such as esterification, etherification, nucleophilic substitution, etc., providing a rich material basis and diverse synthesis paths for the development of organic synthesis chemistry.
What are the physical properties of 4-Hydroxybenxotrifluoride?
4-Hydroxytrifluorotoluene, this substance is colorless to light yellow liquid with a special odor. Its melting point is remarkable, the melting point is about 40-43 ° C, and the boiling point is between 220-222 ° C. Due to the special structure of the intramolecular hydroxyl group and trifluoromethyl group, it has a certain polarity and has good solubility in organic solvents. Like common organic solvents such as ethanol, ether, and acetone, it can be miscible with it, but the solubility in water is relatively small.
Looking at its stability, it is relatively stable at room temperature and pressure. However, when encountering open flames or hot topics, there is a risk of combustion. And the decomposition of hot topics will release toxic gases containing fluorine and sulfur, so caution must be used when storing and using.
The density of this substance is greater than that of water, about 1.44g/cm ³, and the vapor pressure has a corresponding value under specific conditions, which affects its behavior in the gas phase. In the field of organic synthesis, 4-hydroxytrifluorotoluene has a unique structure and is often used as a key intermediate. It participates in the synthesis process of many drugs, pesticides and fine chemicals, and is an important raw material for organic synthetic chemistry.
Is 4-Hydroxybenxotrifluoride chemically stable?
4-Hydroxytrifluorotoluene, its chemical properties are relatively stable. This substance contains trifluoromethyl. Due to the extremely high electronegativity of fluorine atoms, trifluoromethyl has a strong electron-withdrawing effect, which affects the distribution of molecular electron clouds. The hydroxyl groups on the benzene ring interact with it, affecting its chemical activity.
Under normal conditions, 4-hydroxytrifluorotoluene can exist stably in mild environments. In case of strong oxidizing agents, the hydroxyl groups may be oxidized, such as in contact with strong oxidizing substances such as potassium permanganate under suitable conditions, and the hydroxyl groups may be converted to carbonyl groups or even carboxyl groups.
However, in view of the strong electron-absorbing properties of trifluoromethyl, the electron cloud density of benzene ring decreases, so that the electrophilic substitution activity of benzene ring decreases compared with benzene, and it is less prone to electrophilic substitution reactions such as halogenation and nitrification. However, under specific conditions and suitable catalysts, electrophilic substitution reactions can still occur. The substitution position is jointly dominated by the electronic effect of hydroxyl groups and trifluoromethyl groups. Because hydroxyl groups are ortho-para-sites and trifluoromethyl groups are meta-sites, in general, the reaction tends to occur in the ortho or para-sites of hydroxyl groups.
In terms of nucleophilic substitution reactions, due to the influence of trifluoromethyl groups, its reaction activity is different from that of general halogenated aromatics, and specific conditions and
Overall, 4-hydroxytrifluorotoluene is stable under common conditions, but under the action of specific chemical environments and reagents, it can undergo specific chemical reactions and exhibit unique chemical behaviors.
What is 4-Hydroxybenxotrifluoride production method?
In the past, there were many different methods for the preparation of 4-hydroxytrifluorotoluene. The common one is to use p-cresol as the starting material and first use a specific reagent to sulfonate. The sulfonating agent such as p-cresol and sulfuric acid is interacted with at a suitable temperature and time to obtain a sulfonated product.
Then, the sulfonated product is reacted with a fluorinated reagent. This fluorinated reagent, or potassium fluoride, is obtained by replacing the sulfonate group with a fluorine atom under the help of a high temperature and a phase transfer catalyst.
The method of re-oxidation selects a suitable oxidizing agent, such as potassium permanganate, potassium dichromate, etc., in a suitable acid-base environment, temperature and other conditions, the methyl of p-fluorotoluene is oxidized to a carboxyl group to obtain p-fluorobenzoic acid.
Finally, the carboxyl group of p-fluorobenzoic acid is reduced to a hydroxyl group with a specific reducing agent, such as lithium aluminum hydride, etc., to obtain 4-hydroxytrifluorotoluene.
There is another method, starting with p-chlorotrifluorotoluene. React it with alkali metal hydroxide in a system of high temperature and high pressure, phase transfer catalyst, and the chlorine atom is replaced by a hydroxyl group, and 4-hydroxytrifluorotoluene can also be obtained. These two methods have their own advantages and disadvantages, and they are both common ways to prepare 4-hydroxytrifluorotoluene.
What is the price range of 4-Hydroxybenxotrifluoride in the market?
4-Hydroxytrifluorotoluene, in the market price range, varies depending on time and place supply, demand and quality. Looking at the market of chemical materials in the past, the price of such fine chemicals is influenced by many factors.
When it comes to the cost of raw materials, if the initial materials required for their preparation, such as fluorinated compounds and phenols, are abundant in sources and stable in price, the price of 4-hydroxytrifluorotoluene may stabilize. On the contrary, if raw materials are scarce, difficult to mine or affected by policy regulation, the cost will rise, and its market price will also rise.
Furthermore, the difficulty and advanced level of production technology are also key. If the process is complex, requires high-end equipment and fine operation, and consumes a lot of energy, the production cost will be high, and the price will be high. However, if the process is improved, the efficiency will be improved, and the loss will be reduced, the price may be reduced.
The supply and demand relationship in the market is more like leverage in the trade-off. When the market has strong demand for 4-hydroxytrifluorotoluene, which is widely used in industries such as medicine, pesticides and materials, and the demand exceeds the supply, the price will rise. On the contrary, if there is excess capacity and the demand is weak, the price will fall.
Based on the rough estimate of past market conditions, the price per kilogram may be between hundreds and thousands of yuan. For high-quality products that meet high-end application standards, the price may be nearly several thousand yuan per kilogram; for ordinary industrial-grade products, it may be several hundred yuan per kilogram. However, this is only a rough estimate. The actual price must be carefully checked by the current market conditions and consulted with industry merchants, chemical trading platforms and relevant professionals before the exact number can be obtained.