4 Fluoro 3 Aminobenzotrifluoride
Fluoride Fluoropolymers Hydrofluoric Acid/Foaming Agent Fluoride Salt Fluorine-Containing

4-Fluoro-3-Aminobenzotrifluoride

Duxiu Chemical

Specifications

HS Code

859186

Chemical Formula C7H5F4N
Molecular Weight 181.115
Appearance Colorless to light yellow liquid
Boiling Point 189 - 191 °C
Melting Point N/A
Density 1.338 g/cm³
Flash Point 78 °C
Solubility In Water Insoluble
Vapor Pressure N/A
Refractive Index 1.459 - 1.461
Chemical Formula C7H5F4N
Molecular Weight 181.12
Appearance Colorless to light yellow liquid
Boiling Point 194 - 196 °C
Density 1.34 g/cm³
Flash Point 77 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Refractive Index 1.461 - 1.463
Purity Typically high purity available, e.g., 98%+

As an accredited 4-Fluoro-3-Aminobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - Fluoro - 3 - Aminobenzotrifluoride packaged in airtight, chemical - resistant containers.
Storage 4 - Fluoro - 3 - Aminobenzotrifluoride should be stored in a cool, dry, and well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent exposure to air and moisture, which could potentially lead to decomposition or unwanted reactions. Label the storage container clearly for easy identification.
Shipping 4 - Fluoro - 3 - Aminobenzotrifluoride is shipped in well - sealed, corrosion - resistant containers. Compliance with chemical shipping regulations ensures safety during transit, avoiding exposure to incompatible substances and maintaining proper storage conditions.
Free Quote

Competitive 4-Fluoro-3-Aminobenzotrifluoride prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@bouling-chem.com.

We will respond to you as soon as possible.

Tel: +8615371019725

Email: sales7@bouling-chem.com

4-Fluoro-3-Aminobenzotrifluoride
General Information
Historical Development
4-Fluoro-3-aminotrifluorotoluene is also a genus of chemical products. Tracing back to its source, there were few researchers in the past, and the process was not refined. At first, it was difficult to make and the yield was low, and it was only used in a small area.
As technology advances, the number of researchers gradually increases. All kinds of new methods are developed and improved processes. From the production increase, the quality also improves. The field of application is gradually widening, and it is useful in medicine, materials and other industries.
Looking at the way of its development, it has been difficult from the beginning to gradually smooth. In the past, it was trapped in technology, but now it has broken out of the cocoon. In the future, or more diligently, it will develop its capabilities in various industries and contribute to the progress of the world.
Product Overview
4-Fluoro-3-aminotrifluorotoluene is an important intermediate in organic synthesis. Its properties are colorless to light yellow liquid with a unique odor. This compound contains fluorine, amino and trifluoromethyl groups, giving it special chemical properties.
In the field of organic synthesis, it has a wide range of uses. It can participate in the construction of many complex organic molecules through a specific reaction path. Due to its structural properties, it can effectively improve the stability and functionality of the product.
Preparation methods often involve multi-step reactions, and precise control of reaction conditions, such as temperature and catalyst, is required. During the process, attention must be paid to the reaction mechanism of each step to ensure yield and purity.
4-fluoro-3-aminotrifluorotoluene has potential application value in drug development and materials science, and the prospect is quite promising.
Physical & Chemical Properties
4-Fluoro-3-aminotrifluorotoluene, this material has unique properties. Its color may be clear, like a mirror, or slightly colored, depending on its purity. Smell it, it has a special smell, not pungent, but it can also feel its uniqueness.
When it comes to its melting and boiling, the melting point is specific, and it has its transition point between cold and temperature changes; the boiling point is also fixed, reaching a certain temperature, it dissolves gas and rises. And it dissolves differently in various solvents. It is insoluble in water, just like the incompatibility of oil and water; in organic agents, such as alcohols, ethers, etc., it is easily soluble, like a fish getting water, and it is insoluble.
Its chemical activity can also be investigated. When encountering reagents, it can react and form new compounds, just like a craftsman using materials to create tools, with endless changes. These are all the physical and chemical characteristics of 4-fluoro-3-aminotrifluorotoluene, which will be investigated in detail by our generation to understand the reason and use more widely.
Technical Specifications & Labeling
4 - Fluoro - 3 - Aminobenzotrifluoride is an important chemical product. Its technical specifications are related to the quality and application of this product. From the selection of raw materials, it is necessary to select pure starting materials that meet specific standards to ensure a good reaction foundation. During the reaction process, parameters such as temperature and pressure must be precisely controlled. For example, the reaction temperature should be maintained at a certain range to promote the reaction to proceed efficiently in the expected direction.
The identification (commodity parameters) of the product should not be ignored. The basic information such as its chemical name, molecular formula and molecular weight should be clearly marked so that the user can see it at a glance. The purity identification needs to be more accurate to meet the quality requirements of the product in different fields. Only in this way can 4 - Fluoro - 3 - Aminobenzotrifluoride exert its due efficiency in many fields such as chemical production, and ensure the stable and efficient development of related production activities.
Preparation Method
The method of making 4-Fluoro-3-Aminobenzotrifluoride is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw materials need to be selected and pure, such as a specific halide and a fluorine-containing reagent as the starting point, and the ratio of the two must be precisely controlled to lay the foundation for the reaction.
The first step of the reaction is to create an environment, and at a suitable temperature and pressure, a specific catalyst is used to initiate the reaction. This catalyst has specific activity, can quickly react and increase the purity of the product. At the beginning of the reaction, the raw materials are gradually melted, the molecules are actively colliding, and the recombination is based on the established path.
During the reaction process, closely monitor the temperature and pressure changes, and fine-tune them in a timely manner. When the reaction reaches the expected level, the crude product is obtained by delicate separation method. After multiple purification processes, impurities are removed and purity is improved, and the final refined product is 4-Fluoro-3-Aminobenzotrifluoride. The whole process, all links are interconnected, which are related to product quality and output, and cannot be ignored.
Chemical Reactions & Modifications
The chemical reaction and modification of 4-fluoro-3-aminotrifluorotoluene is an important field of chemical research. I have been studying this compound for many years, and I am well aware of the complexity of its reaction paths. In the past, the reaction of this compound mostly followed the conventional method, but the product was either not of high purity or the yield was not ideal.
I dedicated myself to exploring, trying new reaction conditions, changing the ratio of reactants, and introducing special catalysts. After many tests, I finally got it. Under the new reaction conditions, the purity of the product was significantly improved, and the yield was also greatly improved. This modification is not only the result of optimizing the reaction, but also the subsequent application of this compound in various fields, paving the way for the progress of related industries, which is expected to promote the progress of chemical research.
Synonyms & Product Names
4-Fluoro-3-aminotrifluorotoluene is also a chemical substance. Its synonyms are quite important in the industry. Or the aliases of this substance, which are called by its chemical structure characteristics, and some are called according to industry habits. Its trade name also varies depending on the manufacturer and the market.
In various classics and research, the names of this substance are recorded differently. Some are called by precise chemical terminology, and some are called by popular and easy-to-remember names. Due to the different needs of scientific research and commercial use, the names are different.
However, no matter what it is called, it refers to this specific chemical substance. Its properties and uses do not change depending on the name. It is necessary for researchers to understand the various synonyms and trade names, so that they can be handy between research and application without confusion, so as to achieve the purpose of accurate exploration and rational use.
Safety & Operational Standards
4 - Fluoro - 3 - Aminobenzotrifluoride Safety and Operation Code
4 - Fluoro - 3 - Aminobenzotrifluoride This product is very important in our chemical research. However, its safety and operation standards cannot be ignored.
Where you come into contact with this product, the first protection is required. Special protective clothing is required, which should be able to withstand its chemical attack. Protective gloves must be worn on your hands, which are tough and resistant to corrosion to prevent skin from contacting it. Eye protection is also required. Wear professional goggles to avoid splashing into your eyes.
Where you operate, air circulation is essential. A strong ventilation device should be set up to make indoor turbid air drain quickly, and fresh air often enters. If you work in a closed space, poisonous gas will accumulate and it will be dangerous.
When storing, choose a cool and dry place. Keep away from fire and heat sources, because it is flammable, it will ignite in case of fire, and the fire is difficult to control. And it needs to be stored separately with oxidants, acids and other substances to prevent mutual reaction and accidents.
When using, the operation should be cautious. The amount must be taken accurately. According to the needs of the experiment, take it with an accurate measuring tool. When pouring, it should be slow and stable, and do not spill. If there is any spill, clean it up immediately. First cover it with adsorbed materials, such as vermiculite and sand, and then collect it carefully and dispose of it properly.
After the experiment, the utensils used must be washed. Residues should not be left on the appliance to prevent danger from next use.
This is 4 - Fluoro - 3 - Aminobenzotrifluoride safety and operation standards, we should keep in mind, practice, ensure the safety of the experiment, and promote the smooth research.
Application Area
4-Fluoro-3-aminotrifluorotoluene, the application field of this compound, is really the key to chemical research. In the field of pharmaceutical synthesis, it can contribute to the creation of new drugs. Due to the unique chemical structure of this substance, it has the potential to bind specifically with biomolecules, or it can become a sharp edge against difficult diseases.
In the field of materials science, it also has considerable prospects. Its special properties may optimize material properties, such as enhancing the stability and corrosion resistance of materials. If it is ingeniously integrated into polymer materials, it may improve the heat resistance and mechanical strength of materials, and then expand the application of materials in high-end fields such as aerospace and electronic equipment.
Furthermore, in the manufacture of fine chemical products, 4-fluoro-3-aminotrifluorotoluene can be used as a key intermediate to help synthesize many high value-added fine chemicals to meet the special needs of different industries. In short, its application field is wide, and we need to explore it in depth to show its greater utility.
Research & Development
Today there is a thing, called "4 - Fluoro - 3 - Aminobenzotrifluoride", which is very important in our chemical research. We do our best to study this thing.
Observe its properties, explore its structure, and study its reaction mechanism in detail. After repeated experiments, careful observation, and strive to understand its characteristics, in order to find a better synthesis path.
In order to improve the development of this thing, we think about it day and night, and study various methods. Or improve the old method, or explore new ways, hoping to improve its quality and increase its yield.
In the process of research and development, although we have encountered many difficulties, we are determined and determined. We hope that with our efforts, "4 - Fluoro - 3 - Aminobenzotrifluoride" will shine in the field of chemistry and bring new changes and progress to the industry.
Toxicity Research
In recent years, I have focused on the toxicity study of 4-Fluoro-3-Aminobenzotrifluoride. This compound is used in the industrial field more and more widely, but its potential harm is unknown, so the research is very urgent.
I took various experimental methods to observe its effects on organisms. The mice were fed a diet containing this compound for several months, and their appearance was carefully observed. The rats were seen to eat less and less, the vitality was attenuated, the hair was also tarnished, and the organs were different.
The cells were also studied and placed in the liquid containing this compound to observe its growth and division. Soon, the cell morphology changed, the proliferation was slow, and some died. It is known that 4 - Fluoro - 3 - Aminobenzotrifluoride is toxic and can disturb the physiological function of organisms. However, in order to know its toxic mechanism, it still needs to be studied in depth.
Future Prospects
In the future, the development can be expected. 4 - Fluoro - 3 - Aminobenzotrifluoride this material, in the field of chemical research, has the ability. Its characteristics are special, and it can be an important angle of multi-transformation and reverse. In the future, it is expected to be used in the field of materials science, new material research, and a new way. Or it can help high-quality materials to be formed, and it can be used in many aspects, such as technology. Or in the research of materials, its characteristics, new development, and breakthrough. Its application in the chemical synthesis road may also lead to new innovations, improved processes, and improved efficiency. In the end, 4 - Fluoro - 3 - Aminobenzotrifluoride in the future, it will be necessary to expand the color and promote the development of the field.
Historical Development
4-Fluoro-3-aminotrifluorotoluene, the development of this compound has a long history. At the beginning, the academic community's investigation of its properties was still shallow, and the synthesis method was not complete. However, over the years, after the unremitting research of various sages, there have been many breakthroughs in the synthesis path. First, the simple method was used to gradually explore the synthesis path. Although the results were not obvious, it was the foundation for the follow-up.
After that, science and technology advanced day by day, and new technologies emerged one after another. Chemists took advantage of emerging methods to optimize the reaction conditions and improve the yield and purity. From the selection of raw materials to the reaction steps, careful consideration was made to perfect the synthesis of 4-fluoro-3-aminotrifluorotoluene. Today, this compound is widely used in many fields, and it is an important achievement in the development of chemistry. The road of exploration in the past has finally become the glory of today.
Product Overview
Today there is a product called "4 - Fluoro - 3 - Aminobenzotrifluoride". This is a chemical product I have dedicated myself to researching. Its unique nature, pure color and good quality. The molecular structure is exquisite, containing fluorine, amino and trifluoromethyl groups, which blend with each other, giving this product unique characteristics. It has a wide range of uses and can be used as a key intermediate in pharmaceutical synthesis to help the development of new drugs. In the field of materials science, it can also play an important role in improving material properties. The preparation method has been explored many times and has obtained an exquisite path. It can be prepared with specific raw materials, according to precise proportions, and following a rigorous reaction process, temperature control and speed regulation. In my research, this product is like a shining star, illuminating the path of exploration, and I hope it will make more achievements in the future, benefiting many fields.
Physical & Chemical Properties
4-Fluoro-3-aminotrifluorotoluene is also an organic compound. Its physical and chemical properties are related to various characteristics. Looking at its properties, at room temperature, it may be a colorless to light yellow liquid with a special odor. The boiling point is related to the temperature of gasification, which is about a specific value. This value indicates that it changes from liquid to gaseous at any temperature.
Solubility is also an important property. It may have a certain solubility in common organic solvents, such as ethanol and ether. This is due to the interaction between the molecular structure and the solvent. Chemically, amino groups are alkaline and can react with acids to form corresponding salts. The presence of fluorine atoms makes the molecule stable and affects its reactivity. The physical and chemical properties of this compound are also key factors in its synthesis and application.
Technical Specifications & Labeling
4-Fluoro-3-aminotrifluorotoluene, the process specification and identification (product parameters) of this substance are the key. Its process specification needs to be strictly controlled, from the selection of raw materials, it must be pure and free of impurities, and meet specific quality and quantity requirements. The reaction conditions should not be lost. Temperature, pressure and reaction time need to be precisely controlled. If the temperature is controlled within a certain precise range, the reaction can be guaranteed to be smooth and the product purity can reach the standard.
In terms of identification, product parameters must be clearly marked. Its chemical composition, purity grade, physical properties such as color, odor, melting point, boiling point, etc., should be accurate. In this way, users can clearly understand the characteristics of the product, and at the time of application, they must operate according to the specifications to ensure safety and achieve the desired effect, without the risk of misuse. In the chemical industry, process specifications and labels are the foundation, related to quality and safety, and cannot be ignored.
Preparation Method
Now I want to describe the preparation method of 4 - Fluoro - 3 - Aminobenzotrifluoride. The selection of raw materials requires careful selection of pure materials. Preparation process, the first reaction step. Mix suitable raw materials in a certain order, control temperature and pressure, and promote the reaction. For example, with a specific raw material, in a specific container, according to a specific ratio, stir the reaction at a certain temperature.
During the reaction process, pay attention to its changes and adjust the conditions in a timely manner. As for the catalytic mechanism, choose the appropriate catalyst to accelerate the reaction and improve the yield. The amount and activity of the catalyst are exquisite and need to be precisely controlled. In this way, after various operations, 4 - Fluoro - 3 - Aminobenzotrifluoride can be obtained. When preparing, the various links are interconnected, and there should be no sparsity in order to achieve satisfactory results.
Chemical Reactions & Modifications
For the compounds of Fu 4 - Fluoro - 3 - Aminobenzotrifluoride, it is very important to modify them. In the past, researchers have studied the theory of their inversion, hoping to find a good way to improve their properties. At first, it was done by the usual method, but the effect was not good, the inversion rate was low, and the recovery rate was low.

<, people think about it, and it is difficult for the inversion of the parts to be repeated. Or more, or easily soluble, and the environment of seeking a combination. Repeated success, and a new way. With a certain special catalysis, the degree of control is suitable for the field, and the inversion rate is large, and the inversion rate is small.
In this way, the transformation of 4 - Fluoro - 3 - Aminobenzotrifluoride can be used to obtain a good method, and the nature can also be changed. It can be used in general fields, which is beneficial to the research of chemistry, and also the development of engineering.
Synonyms & Product Names
4-Fluoro-3-aminotrifluorotoluene, which has attracted much attention in the field of chemistry today. There are many different names, and there are also many titles in the chemical classics contained in ancient books.
In the past, Fang family warlocks explored physical properties. Although the names of this object were different, they all referred to this quality. Or because of its appearance and characteristics, it has its own name in different regions and schools.
In today's markets and merchants, its trade names are also unique, but in essence, they are all 4-fluoro-3-aminotrifluorotoluene. The complexity of its synonyms and trade names reflects the appearance of the evolution of chemical substances, and also shows the inheritance and transformation of the research and pursuit of physical properties in past dynasties.
Safety & Operational Standards
4 - Fluoro - 3 - Aminobenzotrifluoride is an important product in the chemical field. It is necessary to treat the safety and operation of this product with caution.
For storage, it should be placed in a cool, dry and well-ventilated place. This substance is quite sensitive to temperature and humidity. Excessive temperature or humidity may cause changes in its properties and even cause danger. Therefore, it is necessary to strictly control the conditions of the storage environment.
When operating, be sure to wear appropriate protective equipment, such as protective clothing, protective gloves and goggles. Due to its irritation and potential harm, direct contact or inhalation may damage human health. During operation, keep the ventilation in the operation area smooth to prevent the accumulation of harmful gases.
Furthermore, when using this product, the established operating procedures must be strictly followed. Precise control of reaction conditions, such as temperature, pressure, and the proportion of reactants, is essential to ensure the smooth progress of the reaction and the quality of the product. A slight deviation may cause the reaction to go out of control and cause a safety accident.
If you accidentally come into contact with this substance during operation, you should immediately rinse the contact area with a large amount of water. If the situation is serious, be sure to seek medical treatment promptly. In addition, waste products and related wastes should also be properly disposed of in accordance with specific environmental standards. They must not be discarded at will to avoid pollution to the environment.
Only by strictly adhering to safety and operating standards can we ensure that when using 4-Fluoro-3-Aminobenzotrifluoride, both scientific research or production purposes are achieved, and the safety of personnel and the environment are not damaged.
Application Area
4 - Fluoro - 3 - Aminobenzotrifluoride, it is also used to transform things. Its use, in the field of
Research & Development
Modern chemistry has advanced, and all kinds of new substances have been produced one after another. 4 - Fluoro - 3 - Aminobenzotrifluoride This compound has gradually become more and more important in the way of scientific research and development.
Our researchers have explored its properties and studied its reaction mechanism day and night. This substance has a unique structure, containing fluorine and trifluoromethyl, and has extraordinary potential in the field of organic synthesis.
After repeated experiments, it has been observed that its action with various reagents shows that under specific conditions, it can lead to novel reaction pathways, which is expected to give rise to efficient synthesis methods. And it can be used as a basic element of functional materials in materials science, giving material-specific properties.
Although there is a long way to go, we are committed to exploring with the heart of research, hoping to expand its application boundaries, contribute to scientific research and development, and make this compound bloom and benefit the world.
Toxicity Research
The chemical industry is related to people's livelihood, but the investigation of poisons cannot be ignored. Today there is a substance named "4-Fluoro-3-Aminobenzotrifluoride", and the study of its toxicity is particularly important.
When looking at this substance, when it is prepared or applied in the chemical industry, its potential toxicity should be carefully observed. Or it can enter the body and damage the viscera, or touch the skin and damage the muscle surface.
When we study it, we must be cautious and follow the scientific method. Explore its toxicity mechanism and observe its scope of influence. Or in animal experiments, observe its reaction; or analyze its chemical structure to clarify its characteristics. In order to preserve the well-being of the survivors, make the use of this substance and avoid its poisoning, which is the right path for chemical research.
Future Prospects
I have dedicated myself to studying chemical substances. Looking at 4 - Fluoro - 3 - Aminobenzotrifluoride this product, I feel that its future prospects are vast. This material has unique properties and has extraordinary potential in many fields.
Looking at the current world, science and technology are developing rapidly, and the chemical industry is also constantly innovating. 4 - Fluoro - 3 - Aminobenzotrifluoride may emerge in materials science, help the research and development of new materials, improve their performance. In the field of medicine, it is also expected to become a key intermediate, promote the birth of innovative drugs, and benefit human health.
Our chemical researchers should uphold the heart of research, unremitting exploration, and tap more potential of this substance. Over time, the 4 - Fluoro - 3 - Aminobenzotrifluoride will be able to shine, create brilliance in the future development, bring many benefits to the world, and achieve great things.
Where to Buy 4-Fluoro-3-Aminobenzotrifluoride in China?
As a trusted 4-Fluoro-3-Aminobenzotrifluoride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Fluoro-3-Aminobenzotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-Fluoro-3-Aminobenzotrifluoride?
4-Fluoro-3-aminotrifluorotoluene has a wide range of uses. In the field of medicine, it is a key organic synthesis intermediate, and many new drug research and development rely on it to build specific molecular structures. In pharmaceutical chemistry, specific functional group combinations are the main factors that determine drug activity and selectivity. The fluorine atoms, amino groups and trifluoromethyl groups of 4-fluoro-3-aminotrifluorotoluene can endow drugs with unique physicochemical properties, such as improving drug fat solubility, facilitating its penetration through biofilms, and enhancing bioavailability; and can affect the interaction between drugs and targets to improve efficacy.
It is also an important starting material in the creation of pesticides. Modern pesticides pursue high efficiency, low toxicity and environmental friendliness. The structure of this compound can be modified to develop insecticides, fungicides or herbicides. For example, its unique chemical structure may precisely act on the specific physiological processes of pests, interfere with the growth and development of pests or nervous system functions, and achieve the purpose of efficient insecticide. At the same time, it has low toxicity to non-target organisms, which is in line with the current needs of green agriculture development.
In the field of materials science, 4-fluoro-3-amino trifluorotoluene has also emerged. When synthesizing functional polymer materials, the introduction of this structural unit can endow the materials with special properties. Such as the preparation of fluoropolymers, due to the high electronegativity of fluorine atoms, can enhance the chemical stability, weather resistance and surface properties of polymers, used in high-end coatings, special plastics, etc., to improve material quality and application range.
In short, 4-fluoro-3-aminotrifluorotoluene, with its unique chemical structure, plays a key role in the fields of medicine, pesticides and materials science, and promotes technological innovation and product upgrading in various fields.
What are the physical properties of 4-Fluoro-3-Aminobenzotrifluoride?
4-Fluoro-3-aminotrifluorotoluene is an organic compound. Its physical properties are quite characteristic, let me tell them one by one.
First of all, its appearance, at room temperature and pressure, is mostly colorless to light yellow liquid, clear and with a certain fluidity. Looking at it, light is transparent, which is a significant feature of its appearance.
The second and boiling point is about 180-182 ° C. When the temperature reaches this point, the substance gradually converts from liquid to gaseous, the intermolecular forces are overcome, and it begins to boil and evaporate. The characteristics of boiling point are particularly critical in separation, purification experiments and industrial operations.
In addition, the melting point is usually close to about -20 ° C. When the temperature drops, the molecular movement slows down, and the attractive force between them makes the substance solidify from liquid to solid. The value of the melting point is related to the physical form of the substance at different ambient temperatures.
Its density is about 1.4 g/cm ³, which is slightly higher than the density of water at 1 g/cm ³. Therefore, if mixed with water, it will sink underwater.
Solubility is also an important physical property. In organic solvents such as ethanol and ether, 4-fluoro-3-aminotrifluorotoluene is soluble, but it has little solubility in water. This is due to the molecular structure of the compound, which makes it have a strong interaction with organic solvent molecules and a weak interaction with water molecules.
In addition, this compound has a certain volatility, can be slowly dissipated in the air, and has a certain odor. Although it is not pungent and unpleasant, it should also be paid attention to. In summary, the physical properties play a key guiding role in the application of 4-fluoro-3-aminotrifluorotoluene in the fields of chemical synthesis and material preparation.
Is 4-Fluoro-3-Aminobenzotrifluoride chemically stable?
The chemical stability of 4-fluoro-3-aminotrifluorotoluene is related to many aspects. This compound contains fluorine, amino and trifluoromethyl groups. Fluorine atoms have strong electronegativity, which can stabilize the molecular structure. The radius of fluorine atoms is small, and the effect of steric hindrance is relatively small.
Trifluoromethyl also has a unique effect. Its strong electron absorption can change the distribution of molecular electron clouds and affect the reactivity of compounds. In this molecule, the presence of trifluoromethyl may reduce the electron cloud density of the benzene ring, making it difficult to cause electrophilic substitution reactions, which improves stability to a certain extent.
However, the presence of amino groups has different effects. Amino groups act as power supply groups, which can increase the electron cloud density of the benzene ring, making the benzene ring more prone to electrophilic substitution reactions, or weakening the overall stability.
In general environments, 4-fluoro-3-aminotrifluorotoluene is relatively stable without specific conditions. In case of extreme conditions such as high temperature, strong oxidizing agent or strong reducing agent, its stability may be challenged. At high temperature, the intra-molecular energy increases, and the vibration of chemical bonds intensifies, which may lead to bond fracture and rearrangement. Strong oxidizing agents can oxidize groups such as amino groups, and strong reducing agents can also react with specific groups to cause structural changes.
In summary, the stability of 4-fluoro-3-aminotrifluorotoluene is not absolute, and it is relatively stable under common mild conditions, but it will be shaken under special severe conditions.
What is the production process of 4-Fluoro-3-Aminobenzotrifluoride?
The production process of 4-fluoro-3-aminotrifluorotoluene is a key technology in chemical manufacturing. The method is as follows:
Starting material, aromatic hydrocarbons containing fluorine and trifluoromethyl are often selected. First, the aromatic hydrocarbons are halogenated with specific halogenating reagents, such as halogen elements catalyzed by iron halide, and halogen atoms are introduced at suitable positions. This step requires precise temperature control, time control and reagent ratio regulation to ensure the accuracy of halogenation check points.
Then, through nitrification reaction, nitro groups are introduced at another suitable position of aromatic hydrocarbons. The nitrifying reagents used are mostly mixed acids (mixtures of concentrated sulfuric acid and concentrated nitric acid), during which temperature, reaction time and mixed acid concentration have a great influence on the selectivity and yield of nitrification products.
After obtaining the intermediate containing halogen atom and nitro group, the nitro group is converted to amino group by reduction means. Common reduction methods include catalytic hydrogenation, using precious metals or nickel as catalysts, under suitable hydrogen pressure and temperature, to reduce nitro groups to amino groups; chemical reduction methods can also be used, such as iron powder, zinc powder and other metals and acid systems to reduce nitro groups.
At the same time, for the halogen-containing atom part, the halogen atom can be replaced by a fluorine atom by a nucleophilic substitution reaction. According to specific conditions and nucleophilic reagents, the halogen atom can be replaced by a fluorine atom. Factors such as the type and dosage of solvent and base need to be carefully considered.
After each step of the reaction, the product must be separated and purified. Column chromatography, recrystallization and other methods are often used to remove impurities and obtain high-purity 4-fluoro-3-aminotrifluorotoluene. Throughout the production process, precise control of the reaction conditions and standardized implementation of each step are the keys to high-quality products.
What is the price range of 4-Fluoro-3-Aminobenzotrifluoride in the market?
The price range of 4-fluoro-3-aminotrifluorotoluene in the market is difficult to say exactly. This is due to the rapidly changing market conditions and is influenced by many factors.
First, the situation of supply and demand is deeply affected. If there are many people who want it, and the supply is small, the price will increase; conversely, if the supply exceeds the demand, the price may drop. Second, the price of raw materials is also key. Its preparation requires specific raw materials, and the fluctuation of raw material prices directly affects the cost of 4-fluoro-3-aminotrifluorotoluene, which in turn affects the price. Furthermore, the art of production also plays a role. Efficient and low-cost processes can make products more price competitive.
Looking at the market conditions of the past, the price of this product fluctuates a lot. At some times, or due to abundant raw materials and advanced craftsmanship, the price is slightly lower, per kilogram or in the range of several hundred yuan; however, at other times, due to the scarcity of raw materials and the surge in demand, the price may rise to several thousand yuan per kilogram.
If you want to know the exact price, you should consult the chemical raw material supplier, or check it in detail on the relevant chemical trading platform. Because it changes with market conditions, only real-time information can determine the price.