4 Bromo 2 Iodobenzotrifluoride
Fluoride Fluoropolymers Hydrofluoric Acid/Foaming Agent Fluoride Salt Fluorine-Containing

4-Bromo-2-Iodobenzotrifluoride

Duxiu Chemical

Specifications

HS Code

293141

Chemical Formula C7H3BrF3I
Molar Mass 360.804 g/mol
Appearance likely a colorless to pale yellow liquid
Solubility In Water very low solubility in water, due to non - polar nature
Solubility In Organic Solvents soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure low vapor pressure at room temperature
Stability stable under normal conditions, but may react with strong oxidizing or reducing agents

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Packing & Storage
Packing 100g of 4 - Bromo - 2 - Iodobenzotrifluoride packaged in a sealed, chemical - resistant bottle.
Storage Store 4 - Bromo - 2 - Iodobenzotrifluoride in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances such as strong oxidizing agents. Store in a tightly sealed container to prevent leakage and exposure to air or moisture, which could potentially lead to decomposition or reaction.
Shipping 4 - Bromo - 2 - Iodobenzotrifluoride is shipped in sealed, corrosion - resistant containers. Compliance with hazardous chemical shipping regulations is ensured, with proper labeling indicating its properties for safe transportation.
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4-Bromo-2-Iodobenzotrifluoride
General Information
Historical Development
"The History of 4-Bromo-2-iodotrifluorotoluene"
The author of 4-bromo-2-iodotrifluorotoluene is also a genus of chemical products. Its initial exploration began with the pursuit of organic synthesis by many scholars. In the past, organic chemistry was prosperous, and the public wanted to explore new fields, exploring the wonderful method of substance synthesis.
At that time, the research on halogenated aromatics became more and more popular. 4-Bromo-2-iodotrifluorotoluene, because of its unique structure, contains bromine, iodine and trifluoromethyl, attracted the attention of researchers. At first, the synthesis method was difficult and the yield was quite low. However, many researchers are reluctant to give up. After years of hard work, they have improved their skills and optimized the process. From simple experiments to fine operations, every step has been dedicated.
As the years go by, its synthesis method has become more refined, the yield has gradually increased, and its application has also become wider. In medicine, materials and other fields, it has emerged and made outstanding contributions to the advancement of science and technology.
Product Overview
Today, there is a substance called 4-Bromo-2-Iodobenzotrifluoride. It is a chemical substance, which is either liquid or has a unique color and taste. This substance contains bromine, iodine, and fluorine elements, with a delicate structure and unique properties. The position of bromine and iodine gives it specific reactivity, and it can be used as a key intermediate in the field of organic synthesis. Because of its fluorine content, it has special physical and chemical properties, such as high stability and low surface tension. It has potential uses in chemical and pharmaceutical research and development. It can help synthesize novel drug molecules or optimize the properties of materials. Although its properties and uses still need to be further explored, it has already shown its important value in scientific research and industrial production, and will surely contribute to the development of various fields in the future.
Physical & Chemical Properties
4 - Bromo - 2 - Iodobenzotrifluoride, organic compounds are also. Their physical and chemical properties are related to chemical research. This substance is at room temperature, or in a liquid state, with a specific color and taste. Its boiling point and melting point are the key to physical properties. In terms of chemistry, its molecular structure contains bromine, iodine and trifluoromethyl, so its reactivity is unique. The halogen atoms of bromine and iodine make it active in reactions such as nucleophilic substitution. The existence of trifluoromethyl affects the distribution of its electron cloud, causing its chemical behavior to be different from others. The study of the physical and chemical properties of this substance is of far-reaching significance in the fields of organic synthesis and materials science, and can provide a solid theoretical foundation for the creation of new compounds and the development of new materials.
Technical Specifications & Labeling
4 - Bromo - 2 - Iodobenzotrifluoride is a unique compound. Its preparation process depends on a precise process. First, select high-purity raw materials, which is the basis. The quality of the raw materials is related to the quality of the product. Then in a suitable reaction vessel, control the temperature and pressure, so that the reactants can react in an orderly manner according to a specific ratio. The reaction process must be strictly observed, such as observing the change of temperature. After the reaction is completed, the pure 4 - Bromo - 2 - Iodobenzotrifluoride can be obtained by separation and purification.
Its quality identification is based on a number of indicators. Looking at its color, it should be clear and pure, without variegated stains. Measure its purity, with precision instruments, to achieve extremely high values. Measuring its melting point and boiling point must conform to the established standards. In this way, it can be said that this product is suitable for industrial or scientific research needs and can be used in various fields.
Preparation Method
If you want to make 4 - Bromo - 2 - Iodobenzotrifluoride, you must study the raw materials and production process, reaction steps and catalytic mechanism in detail. The raw materials should be selected to be pure and suitable, such as compounds containing fluorine, bromine and iodine, to ensure a smooth reaction. The production process needs to be carefully planned, and temperature control, pressure control and reaction time are all critical.
At the beginning of the reaction step, the fluorine-containing substrate and brominated reagent are mixed in a specific ratio, and the reaction is initiated at a suitable temperature, so that the fluorine group and bromine group are bound in an orderly manner. Then, the iodizing reagent is introduced, and the iodine atom is properly integrated to achieve the desired molecular structure through precise regulation.
The catalytic mechanism is also important. The selection of high-efficiency catalysts can reduce the activation energy of the reaction and accelerate the reaction process. Or use metal catalysts, with their special electronic structure, to promote atomic rearrangement and bonding. In this way, after careful planning of each link, it is expected to efficiently prepare 4-Bromo-2-Iodobenzotrifluoride.
Chemical Reactions & Modifications
Fu 4 - Bromo - 2 - Iodobenzotrifluoride This substance, in the field of chemical synthesis, its reaction and modification are quite critical. The method of the past is often complicated and the yield is not good.
Looking at the chemical reaction of it now, if you want to find the best effect, you should study the conditions of the reaction. If the temperature is controlled, the reaction will be delayed if it is too low, and if it is too high or the side effects will be overgrown. And the purity and ratio of the reagent used also affect the success of the reaction.
As for the modification, he can be introduced to change its properties. Or increase its stability, or change its activity. After many attempts, if a specific reagent is reacted at a suitable temperature and pressure, the quality and quantity of the product can be improved.
However, the research of chemistry is never-ending. Although it has been achieved now, it still needs to be explored in the future, hoping to get better methods for the reaction and modification of 4-Bromo-2-Iodobenzotrifluoride to advance chemistry.
Synonyms & Product Names
4 - Bromo - 2 - Iodobenzotrifluoride, the synonyms and trade names of this object are the key to my chemical research. During my research process, I have carefully studied many classics, hoping to clarify the changes in its appellation.
In the past, the academic community called this object either according to its chemical structure characteristics, or according to the situation of its initial discovery. However, with the deepening of research, many synonyms have emerged. Some are named for their elemental composition, and some are named for their reaction characteristics. As for the name of the product, merchants mostly seek to be concise and easy to remember, in order to facilitate promotion. Therefore, they may take its key ingredients or use figurative words to recognize its characteristics.
I am well aware that the identification of synonyms and trade names of this thing is of great significance to chemical research and industrial applications. It can help researchers communicate accurately and avoid ambiguity; in industrial production, it can also enable all parties to clarify the things involved and move freely. So I often study to know the details, and make a small contribution to the progress of chemical research.
Safety & Operational Standards
4 - Bromo - 2 - Iodobenzotrifluoride is a halogen-containing organic compound, which is related to its safety and operating standards. When it is said in ancient Chinese, it can be expressed as follows:
4 - Bromo - 2 - Iodobenzotrifluoride is an organic compound, containing halogen elements. In the handling and storage of this thing, strict regulations must be followed to avoid risks.
This thing has the properties of halides, or there is a risk of irritation and poisoning. Touch it, it can damage the skin, eyes and breathing. Therefore, when handling, it is necessary to wear protective equipment, such as gloves, goggles, and anti-virus masks, and in a well-ventilated place to make the foul gas dissipate quickly and avoid harm to the body.
When storing, it should be placed in a cool, dry and ventilated place, away from fire and heat sources, to prevent it from being decomposed by heat and causing accidents. It should also be stored separately from oxidizing agents, alkalis and other substances to avoid their contact and reaction.
If there is a leak, the first thing to do is to evacuate everyone and prohibit unrelated people from approaching. The operator must wear protective clothing and clean the leak according to the specifications. When there is a small leak, it can be adsorbed by sand, vermiculite and other substances and put into a closed container; when there is a large leak, it needs to be blocked by an embankment and recycled or treated with professional equipment, so as not to pollute the environment.
Anyone who handles this thing must first know its nature, be familiar with the rules of its survival and handling, and practice it strictly, so that the security will be safe and everything will go well.
Application Area
4 - Bromo - 2 - Iodobenzotrifluoride is a unique chemical substance with a wide range of application fields. In the field of medicinal chemistry, this substance may be a key raw material for the synthesis of specific drugs. Because of its unique chemical structure, it can precisely combine with specific targets in organisms and help create new drugs for the treatment of difficult diseases.
In the field of materials science, 4 - Bromo - 2 - Iodobenzotrifluoride may be used to prepare materials with special properties. Through its participation in chemical reactions, it can improve the stability, heat resistance and corrosion resistance of materials, and has potential value in high-end material manufacturing.
Furthermore, in the field of organic synthetic chemistry, it can be used as an important synthetic building block. Chemists can use ingenious reaction design to construct complex and diverse organic molecular structures, which can contribute to the development of organic synthetic chemistry. All of this shows that 4 - Bromo - 2 - Iodobenzotrifluoride in various application fields, all of which cannot be ignored.
Research & Development
To taste the way of scientific research lies in unremitting research. Today there is a thing, named 4 - Bromo 2 - Iodobenzotrifluoride. Our generation has worked hard to explore its mysteries.
At the beginning, analyze its structure, gain insight into its characteristics, and clarify its reaction rules. Then set up various experiments, and after repeated trials, observe its changes under different conditions.
In the study of the reaction mechanism, I dare not slack off in the slightest. Strive to clarify the reason for each step, so that the path is obvious.
After long-term efforts, gradually gain something. In the synthesis method, find a way to optimize, hoping to increase the yield and reduce its cost. This is our wish for scientific research, hoping that this object will shine in many fields in the future, driving the wheel of development forward and seeking the well-being of the world.
Toxicity Research
Today there is a thing, named 4 - Bromo - 2 - Iodobenzotrifluoride. I am a chemical researcher, and I have studied its toxicity. The color, state, and taste of this thing have been carefully observed. After experimental investigation, its effects on organisms have been tested one by one. Looking at its contact with different substances, the changes that occur are recorded in the book.
Toxicity test, test it with all kinds of organisms. See it in the body of microinsects, which can disrupt its physiological order, causing its movement to be perverse and growth to be blocked. On green plants, it can damage its leaves, hinder its photosynthesis, and its vitality gradually decays. And when it enters water, it can be a sewage source, and all things in the water are affected by it.
I am well aware of the importance of toxicity research, which is related to the safety of all living beings. Therefore, I study day and night, hoping to obtain the truth, avoid its harm for the world, and use its benefits, so that this chemical substance will not be a disaster to the world, but can be used by everyone and benefit the world.
Future Prospects
Husband 4 - Bromo - 2 - Iodobenzotrifluoride, the thing of transformation is also. Today, this thing has its own characteristics and uses. In the future, there must be extraordinary benefits.
With its properties, anti-activity, it can be synthesized from a variety of raw materials. Unknown, or can be used in the new research field, large-scale color. The new system requires a lot of special compounds, this 4 - Bromo - 2 - Iodobenzotrifluoride may be able to provide it with the best quality, help the step, solve the disease of life.
And in the material science, it is also expected to be important. Or new functional materials can be developed, such as materials with special properties and light properties, to promote the development of electronics, light, etc.
I am convinced that in the next few days, 4 - Bromo - 2 - Iodobenzotrifluoride will be the best way to improve science and technology, and take the best steps to expand the new environment and add luster to human well-being.
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Frequently Asked Questions

As a leading 4-Bromo-2-Iodobenzotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-Bromo-2-Iodobenzotrifluoride?
4-Bromo-2-iodotrifluorotoluene has a wide range of uses. In the field of organic synthesis, it can be called a crucial intermediate.
It can be used to create a wide variety of drugs. Due to the design and construction of drug molecules, specific functional groups and structural fragments are often introduced, and the functional groups of 4-bromo-2-iodotrifluorotoluene, such as bromine, iodine and trifluoromethyl, can be connected to other organic molecules through various chemical reactions to construct drug molecular structures with specific biological activities. For example, in the research and development process of some anti-tumor drugs, compounds with inhibitory effect on tumor cell growth can be synthesized from this starting material through multi-step reaction.
In the field of materials science, it also has good performance. It can be used to prepare polymer materials with special properties. Due to the existence of trifluoromethyl, it can endow materials with characteristics such as excellent corrosion resistance and low surface energy. By introducing 4-bromo-2-iodotrifluorotoluene into the polymer chain, high-performance materials can be prepared for applications in aerospace, electronic devices and other fields. For example, in the aerospace field, the application of such materials can improve the corrosion resistance of aircraft parts and prolong their service life.
In the field of pesticides, 4-bromo-2-iodotrifluorotoluene also plays an important role. It can be used as a key intermediate for the synthesis of new pesticides. With its unique chemical structure, the synthesized pesticides often have the advantages of high efficiency, low toxicity and environmental friendliness, which helps to improve the yield and quality of crops while reducing the negative impact on the environment. For example, the synthesis of certain pesticides can effectively kill pests and have low toxicity to non-target organisms.
What are 4-Bromo-2-Iodobenzotrifluoride synthesis methods?
The synthesis method of 4-bromo-2-iodotrifluorotoluene is described in many ancient books. One common one is to use compounds containing benzene rings as starting materials, and add bromine and iodine atoms by halogenation reaction. For example, suitable benzene derivatives can be taken first, and under specific reaction conditions, bromination is performed with brominating reagents. Among the brominating reagents, liquid bromine, N-bromosuccinimide, etc. can be selected. The reaction needs to be catalyzed by a suitable catalyst such as iron or iron salt, and carried out in a suitable solvent such as dichloromethane, etc., so that bromine atoms are introduced at specific positions in the benzene ring.
Next, the iodization reaction is carried out with an iodizing reagent. The iodizing reagent can be selected from potassium iodide, cuprous iodide, etc., with appropriate ligands and bases, in a specific organic solvent such as N, N-dimethylformamide, under heating and other conditions, the iodine atom is connected to the bromine atom at the ortho-position of the benzene ring, and then the structure of 4-bromo-2-iodine is constructed.
There is another way, starting with the phenyl series that already contains trifluoromethyl. The substance is first selectively halogenated. According to the positioning effect of the substituent on the benzene ring, the reaction conditions and halogenation reagents are cleverly selected to make the bromine and iodine atoms connect at the desired position. In this process, the precise regulation of reaction conditions is crucial, such as temperature, reaction time, and the ratio of reagent dosage, which all have a significant impact on the reaction process and the yield and purity of the product.
Another literature mentions that the coupling reaction catalyzed by transition metals is used to synthesize. Using bromine, iodine precursors and trifluoromethylation reagents as raw materials, under the action of transition metal catalysts such as palladium and nickel, with the help of ligands, in a suitable base and solvent system, the target molecular structure is constructed through coupling reaction. This approach can effectively avoid the accumulation of impurities in the multi-step reaction and improve the purity and yield of the product. However, this method requires strict reaction conditions and catalysts, and the cost is relatively high.
What are the physical properties of 4-Bromo-2-Iodobenzotrifluoride?
4-Bromo-2-iodotrifluorotoluene is an important compound in organic chemistry. Its physical properties are unique and related to the application and reaction characteristics of this compound.
First of all, under normal temperature and pressure, 4-bromo-2-iodotrifluorotoluene is mostly colorless to light yellow liquid, with clear texture and fluidity. This appearance characteristic can be used as a preliminary basis for identification in many chemical processes and laboratory operations.
As for the boiling point, it is about 190-200 ° C. The importance of boiling point lies in the separation and purification of substances. During distillation operation, controlling this boiling point range can effectively separate 4-bromo-2-iodotrifluorotoluene from the mixed system to obtain a pure product.
In terms of melting point, its melting point is low, roughly around -20 ° C. The low melting point keeps the compound in a liquid state at room temperature, which is convenient for various solution preparation and reaction operations. In a low temperature environment, it is necessary to pay attention to its solidification characteristics so as not to affect the relevant working process.
The density is about 2.1 - 2.3 g/cm ³, which is higher than that of common organic solvents. This density property is of great significance in separation processes such as liquid-liquid extraction, which can be used to achieve effective stratification and separation of this compound from other liquids by means of density differences.
Solubility is also a key physical property. 4-Bromo-2-iodotrifluorotoluene is insoluble in water because water is a polar molecule, and the polarity of this compound is weak. According to the principle of "similar compatibility", the two are incompatible. However, it is soluble in most organic solvents, such as dichloromethane, chloroform, toluene, etc. This solubility makes it convenient to select suitable solvents in organic synthesis reactions, build a reaction environment, and promote the smooth progress of the reaction.
The physical properties of 4-bromo-2-iodotrifluorotoluene, such as appearance, boiling point, melting point, density and solubility, play a decisive role in its application in organic synthesis, chemical production and analysis and testing. In-depth understanding of these properties can better control the compound.
What are the chemical properties of 4-Bromo-2-Iodobenzotrifluoride?
4-Bromo-2-iodine trifluorotoluene, an organic compound. Its chemical properties are unique and it plays an important role in many organic synthesis reactions.
In terms of its reactivity, the presence of bromine and iodine atoms in the molecule makes it highly reactive. Bromine and iodine are both halogen elements, and the presence of halogen atoms makes this compound prone to nucleophilic substitution. In the presence of suitable nucleophiles, bromine or iodine atoms can be replaced by nucleophiles. For example, if sodium alcohol is used as a nucleophilic reagent, under suitable conditions, bromine or iodine atoms can be replaced by alkoxy groups to form corresponding ether compounds. In this process, the nucleophilicity of nucleophiles, reaction temperature, solvent and other factors have a significant impact on the reaction process and product formation.
Furthermore, due to the strong electron absorption of trifluoromethyl, the electron cloud density distribution on the benzene ring will be affected. Trifluoromethyl reduces the electron cloud density of the benzene ring, making the electrophilic substitution reaction on the benzene ring relatively difficult. Compared with similar benzene series compounds without trifluoromethyl, the electrophilic substitution requires more severe reaction conditions, and the substitution position is also affected by the positioning effect of trifluoromethyl. Usually, electrophilic reagents tend to attack positions on the benzene ring that are far away from the trifluoromethyl and have relatively high electron cloud density.
In addition, the carbon-halogen bond in the molecule of 4-bromo-2-iodotrifluorotoluene can undergo a reduction reaction under certain reduction conditions, and the halogen atoms can be removed by reduction to form benzene derivatives without halogen atoms. However, this reduction reaction requires the selection of suitable reducing agents and reaction conditions to ensure the selectivity and efficiency of the reaction.
In summary, the chemical properties of 4-bromo-2-iodotrifluorotoluene are determined by the halogen atoms and trifluoromethyl atoms it contains. In the field of organic synthesis, its active reactivity provides various possibilities for the construction of various organic compounds.
What is the price range of 4-Bromo-2-Iodobenzotrifluoride in the market?
4-Bromo-2-iodotrifluorotoluene is on the market, and its price range is difficult to determine. The price of this product often changes for a variety of reasons.
First, the cost of production is the main factor. If the price of raw materials fluctuates, the price of 4-bromo-2-iodotrifluorotoluene will fluctuate. If the bromide, iodide and fluorine-containing raw materials required for preparation are required, the price may vary due to the amount of minerals, the difficulty of production process, and changes in market supply and demand, which in turn affects the cost and price of this product.
Second, the complexity of the preparation process is also related. If the process is complex, requires multiple steps, high conditions, and the yield is not high, the cost will rise and the price will follow. Fine synthesis operations, strict control of reaction conditions, and complicated purification processes can all increase the cost, making it high in the market.
Furthermore, the situation of market supply and demand is the key. If there are many people, and the supply is limited, the price will rise; if the supply exceeds the demand, the price will fall. If the demand for this product in the pharmaceutical, materials and other industries increases sharply, but the production supply is not sufficient, the price will rise; conversely, if there is excess capacity and the demand is low, the price will go down.
In addition, regional differences also affect the price. Different places have different prices due to differences in transportation costs, tax policies, and market competition. In places with convenient transportation and fierce market competition, the price may be relatively low; in remote places with small markets, the price may be high.
From the above, the market price of 4-bromo-2-iodotrifluorotoluene ranges from a few yuan to a few tens of yuan per gram, but this is only a rough estimate. The actual price depends on the specific time, place, and supply and demand conditions.