As a leading 4-Bromo-2,3,5,6-Tetrafluorobenzotrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the main use of 4-Bromo-2,3,5, 6-Tetrafluorobenzotrifluoride
4-Bromo-2,3,5,6-tetrafluorotrifluorotoluene is widely used. In the field of medicine, it is often used as a key intermediate to help synthesize many specific drugs. Due to the fluorine atom, it can significantly change the physiological activity, lipophilic and metabolic stability of the compound, making the drug more effective and less side effects. For example, in the development of some anti-cancer drugs, it can optimize the molecular structure of the drug, enhance the targeting and inhibitory effect on cancer cells.
In the field of pesticides, it is also an important raw material. With its unique chemical structure, it participates in the synthesis of highly efficient, low-toxic and environmentally friendly pesticides. Fluorinated pesticides have strong insecticidal, bactericidal and herbicidal activities, which can effectively prevent and control crop diseases and pests, improve crop yield and quality, and reduce environmental pollution and impact on non-target organisms.
In the field of materials science, 4-bromo-2,3,5,6-tetrafluorotoluene also has important uses. It can be used to prepare fluorinated polymer materials, which have excellent heat resistance, chemical corrosion resistance and electrical properties. For example, it is used to make high-performance insulating materials for electronic devices to ensure stable operation in complex environments; or it is used to produce special coatings, which give materials good anti-corrosion, wear resistance and self-cleaning properties. It is widely used in high-end fields such as aerospace and automotive manufacturing.
What are the physical properties of 4-Bromo-2,3,5, 6-Tetrafluorobenzotrifluoride
4-Bromo-2,3,5,6-tetrafluorotrifluorotoluene is a kind of organic compound. Its physical properties are unique and of certain importance.
This compound exists in a liquid state under normal temperature and pressure. Looking at its color, it is usually colorless and transparent, with a pure and clear appearance, like a crystal clear liquid. Its smell is slightly irritating, and its unique smell can be sensed when smelled.
In terms of density, it is slightly heavier than water, so when mixed with water, it will sink to the bottom of the water. In terms of boiling point, due to the characteristics of molecular structure, it will transform from liquid to gaseous at a certain temperature range. Its melting point is relatively low, which means that it can maintain a liquid state near room temperature.
In terms of solubility, it exhibits good solubility in organic solvents, such as common ethanol and ether, and can blend with these organic solvents to form a uniform solution. However, in water, its solubility is quite limited, and the two are difficult to mix thoroughly.
The physical properties of 4-bromo-2,3,5,6-tetrafluorotoluene make it have specific uses and values in organic synthesis and other fields, and can provide unique reaction environments and conditions for many chemical reactions.
Is 4-Bromo-2,3,5, 6-Tetrafluorobenzotrifluoride chemically stable?
4-Bromo-2,3,5,6-tetrafluorotrifluorotoluene, this is an organic compound with relatively stable chemical properties. Due to its molecular structure, many fluorine atoms surround the benzene ring, and the electronegativity of fluorine atoms is quite high, which can increase the C-F bond energy and make the molecular structure more stable.
Looking at its stability, under normal conditions, it has a certain tolerance to heat, light and common chemical reagents. Excellent thermal stability, in a moderate heating environment, the molecular structure is difficult to damage. This characteristic is due to the high bond energy of the C-F bond, and more energy is required to break it.
In terms of chemical reactivity, due to the bromine atoms on the benzene ring, nucleophilic substitution can occur. However, due to the influence of the electronic effect of the fluorine atoms around the benzene ring, this reactivity may be slightly lower than that of conventional halogenated aromatics. The electron-absorbing induction effect of fluorine atoms reduces the electron cloud density of the benzene ring, which is not conducive to the attack of nucleophilic reagents.
In terms of oxidation and reduction reactions, the compound is usually stable. Since there are no active functional groups in the molecule that are easily oxidized or reduced, it is difficult for general oxidizing agents and reducing agents to interact with it.
In common organic solvents, 4-bromo-2,3,5,6-tetrafluorotoluene has a certain solubility and is soluble in halogenated hydrocarbon organic solvents such as dichloromethane and chloroform. This solubility is related to the polarity of its molecular structure. Although the polarity of the molecule is changed due to the fluorine atom, the whole still has a certain ability to interact with organic solvents.
In summary, 4-bromo-2,3,5,6-tetrafluorotoluene has relatively stable chemical properties. Although it can participate in some reactions under certain conditions, its stability makes it easier to control during storage and use.
What is the preparation method of 4-Bromo-2,3,5, 6-Tetrafluorobenzotrifluoride
The preparation method of 4-bromo-2,3,5,6-tetrafluorotoluene is an important research topic in the field of chemical synthesis. The preparation method is often obtained by bromination with fluoroaromatic hydrocarbons as starting materials.
Common starting materials, or 2,3,5,6-tetrafluorotoluene. To carry out bromination reaction, suitable brominating reagents can be selected, such as liquid bromine ($Br_2 $), and supplemented with catalysts. The catalyst is often Lewis acid, such as iron tribromide ($FeBr_3 $) or aluminum trichloride ($AlCl_3 $). Under suitable reaction conditions, such as specific temperature and reaction time, liquid bromine can be substituted with 2,3,5,6-tetrafluorotrifluorotoluene under the action of a catalyst, and bromine atoms are introduced at specific positions in the benzene ring to generate the target product 4-bromo-2,3,5,6-tetrafluorotrifluorotoluene.
The reaction temperature is quite critical. If it is too high, it may cause an increase in side reactions and affect the purity of the product. If it is too low, the reaction rate will be slow and take a long time. Generally speaking, the reaction temperature may be controlled between room temperature and tens of degrees Celsius, depending on the specific reaction system.
The reaction time also needs to be precisely controlled. If it is too short, the reaction will not be completed and the raw material will remain. If it is too long, it may damage the product or increase the side reaction. The reaction process is often monitored by thin-layer chromatography (TLC) or gas chromatography (GC), and the reaction can be stopped when the raw material is basically completely reacted.
After the reaction is terminated, a series of post-processing steps are required to purify the product. Usually washed with water to remove water-soluble impurities; then extracted with an organic solvent to collect the organic phase; then dried the organic phase to remove residual water; finally by distillation or column chromatography, high-purity 4-bromo-2,3,5,6-tetrafluorotrifluorotoluene is obtained.
This preparation method, although mainly based on a specific starting material and bromination reaction, may also have other variants, or involve different raw material selection, reaction conditions optimization, or the use of other brominating reagents, all of which are the exploration directions for improving the yield and purity of the product.
What is the price range of 4-Bromo-2,3,5 6-Tetrafluorobenzotrifluoride on the market?
4-Bromo-2,3,5,6-tetrafluorotrifluorotoluene, the price of this product in the market is difficult to set, due to a variety of reasons.
First, the supply and demand situation, the price is very large. If there are many people in the market, but the supply is scarce, the price will rise; on the contrary, if there are few people in the market and there is more supply, the price may drop. For example, when the electronics industry is booming and the demand for it increases sharply, the price will also rise.
Second, the manufacturing cost is also the key. If the price of raw materials fluctuates sharply, the price of the product will follow. If the price of bromine, fluoride and other raw materials required increases due to changes in the place of origin and policy adjustments, the cost of this product will increase and the price will also increase. And in the manufacturing process, energy consumption, labor and other costs will affect the final price.
Third, the quality difference leads to different prices. High purity, the process is complicated, the cost is high, and the price is high; and those with less purity, the price may be slightly lower. For example, in the field of fine chemicals, the purity requirements are extremely high. Although the price of high purity 4-bromo-2,3,5,6-tetrafluorotoluene is high, the demand still exists.
Fourth, market competition is also a price variable. There are many manufacturers and intense competition, in order to occupy the market or reduce prices to promote sales; if the market is monopolistic, the price is more vulnerable to manipulation.
To sum up, its market price fluctuates roughly between hundreds and thousands of yuan per kilogram, but the specific number is difficult to determine, and it must be studied in detail according to the current market conditions.