4 Amino 5 Chloro Benzotrifluoride
Fluoride Fluoropolymers Hydrofluoric Acid/Foaming Agent Fluoride Salt Fluorine-Containing

4-Amino-5-Chloro-Benzotrifluoride

Duxiu Chemical

Specifications

HS Code

371534

Chemical Formula C7H5ClF3N
Molecular Weight 195.57
Appearance Typically a colorless to light yellow liquid
Boiling Point Around 200 - 210 °C
Density Approx. 1.3 - 1.4 g/cm³
Solubility In Water Poorly soluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
Flash Point Probably in the range of 80 - 90 °C
Odor May have a pungent or characteristic organic odor
Chemical Formula C7H5ClF3N
Molecular Weight 195.57
Appearance A solid (usually white to off - white powder)
Melting Point Typically in a certain range (e.g., around 50 - 55 °C)
Boiling Point Appropriate boiling point value depending on pressure conditions
Density Specific density value (g/cm³)
Solubility Soluble in some organic solvents like dichloromethane, less soluble in water
Purity High - purity grades available, e.g., 98% or higher
Flash Point Relevant flash point value
Odor May have a characteristic organic odor

As an accredited 4-Amino-5-Chloro-Benzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - Amino - 5 - Chloro - Benzotrifluoride packaged in air - tight plastic bags.
Storage Store 4 - Amino - 5 - Chloro - Benzotrifluoride in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials like stainless steel or certain plastics. This helps prevent degradation and potential leakage, ensuring its stability and safety during storage.
Shipping 4 - Amino - 5 - Chloro - Benzotrifluoride is shipped in well - sealed containers, compliant with chemical transport regulations. Packaging safeguards against leakage. Shipment is via approved carriers, ensuring safe and proper handling during transit.
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4-Amino-5-Chloro-Benzotrifluoride
General Information
Historical Development
4-Amino-5-chlorotrifluorotoluene, the development of this substance, although it is difficult to study in detail at the beginning. However, looking at the evolution of modern chemistry, the method of its preparation has been gradually refined. At the beginning, there were many difficulties and obstacles in exploring the synthesis path. All kinds of attempts have failed again and again.
As time goes by, the chemical technology has become more and more mature, and the synthesis method has become more and more complete. The scientific researchers have worked hard to improve the process, so that the yield has gradually increased and the quality has been better. From the initial ignorance and exploration, to the orderly preparation of this compound today, the development of this compound has witnessed the progress of the chemical field. In the past, everyone worked together to study and achieve this result. Its historical evolution is really an important chapter in the development of chemistry.
Product Overview
4-Amino-5-chlorotrifluorotoluene is also a chemical product developed by us. This product has unique properties, its shape may be powder, color may be light yellow. Its chemical structure is exquisite, and the 4-amino group is associated with the 5-position chlorine atom and the trifluoromethyl group, giving it specific chemical activity.
In the reaction, it is often used as a key intermediate. Because the amino group is nucleophilic, the chlorine atom is replaceable, and the trifluoromethyl group gives the molecule a unique electronic effect, it can be involved in a variety of organic synthesis reactions, such as nucleophilic substitution and coupling.
It is used in many fields, in the synthesis of medicine, or as a key raw material for the preparation of special drugs; in material science, it can also contribute to the creation of new materials. Our researchers are working tirelessly on this product, hoping to tap its potential, so as to promote the progress of chemical technology and benefit the world.
Physical & Chemical Properties
4-Amino-5-chlorotrifluorotoluene has unique physical and chemical properties. Looking at its shape, it is usually a colorless to slightly yellow liquid at room temperature, clear and clear. Its taste has a slightly special smell.
In terms of its boiling point, it is about in a specific temperature range. This characteristic makes it possible to control the corresponding temperature when separating and purifying. The melting point is also a certain value, reflecting the critical conditions for the transformation of its solid state and liquid state.
As for solubility, it shows different degrees of solubility in many organic solvents. In some polar solvents, it is well soluble; in non-polar solvents, it is slightly soluble or even insoluble. The presence of amino groups with chlorine and trifluoromethyl groups makes them capable of participating in various chemical reactions, such as nucleophilic substitution, electrophilic substitution, etc., which is of great value in the field of organic synthesis.
Technical Specifications & Labeling
4-Amino-5-chlorotrifluorotoluene is a chemical we have painstakingly studied. Its process specifications and identification (product parameters) are crucial.
In terms of process specifications, it is necessary to clarify the method of synthesis. The selection of raw materials should be accurate, and the reaction conditions must be strictly controlled. Temperature, pressure, and catalyst dosage are all related to the purity and yield of the product.
In terms of identification (product parameters), purity is a very high standard, and the impurity content must be minimal. The appearance and color should also meet specific requirements, and the physical and chemical properties such as melting point and boiling point should be accurately determined and recorded in detail. Only in this way can we ensure that the quality of 4-amino-5-chlorotrifluorotoluene is good, and it can be properly applied in various fields, so as to live up to the painstaking research.
Preparation Method
The method of preparing 4-amino-5-chlorotrifluorotoluene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are selected from compounds containing specific groups, such as a halogenated aromatic hydrocarbon and related reagents containing amino groups and trifluoromethyl groups.
In the production process, the reaction temperature is first controlled in a moderate range, about XX to XX degrees Celsius, to achieve the best reaction activity. The first step of the reaction is to mix the halogenated aromatic hydrocarbon and the reagent in a specific solvent, stir well, and introduce a specific catalyst to promote the reaction between the two. The catalyst is prepared in precise proportions, and its unique catalytic mechanism reduces the activation energy of the reaction and accelerates the chemical bond breaking and recombination. Pure product of 4-amino-5-chlorotrifluorotoluene was obtained by separation and purification after stable reaction.
Chemical Reactions & Modifications
Yu has dedicated himself to the research of chemical products. Today, 4-amino-5-chlorotrifluorotoluene is the subject of discussion. The key to chemical reactions is the change of their quality and properties.
The preparation of 4-amino-5-chlorotrifluorotoluene, the reaction path is often related to a variety of reagents and conditions. In the past, the reaction method may have complicated and inefficient disadvantages, the yield is not ideal, and side reactions are frequent, making the purity of the product difficult to control.
However, the way of science lies in continuous change. Today's research strives to optimize its reaction. From the selection of catalysts to the precise regulation of reaction temperature and time, it is necessary to improve. The introduction of new catalysts can greatly increase the reaction activity, reduce the reaction barrier, and increase the reaction rate. The delicate control of temperature makes the reaction move towards the direction of the main product generation and inhibits side reactions.
After many changes, the yield of 4-amino-5-chlorotrifluorotoluene has been significantly improved, and the purity of the product has also been greatly improved. This is the result of unremitting exploration by chemical researchers, reform and innovation, and is expected to contribute to the development of related fields.
Synonyms & Product Names
4-Amino-5-chlorotrifluorotoluene, its synonymous name and the name of the product, are all subject to careful investigation by our chemical researchers. Its synonymous name, or varies due to different academic veins and regional habits, all refer to this specific chemical quality. As for the name of the product, it also varies according to the business plan and positioning.
In the field of chemistry, only by clearly distinguishing the name of the synonym can we study the classics and exchange the academic. Knowing the name of the product gives insight into the practical application and operation of the industry. 4-Amino-5-chlorotrifluorotoluene, its synonymous name and the name of the product, are like two paths to explore the mysteries of this chemical substance, helping us to gain a deeper understanding of its characteristics, uses and value, so as to promote the progress of chemical research and benefit the world.
Safety & Operational Standards
Safety and Operation Specifications for 4-Amino-5-chlorotrifluorotoluene
F 4-Amino-5-chlorotrifluorotoluene is also an important raw material for chemical synthesis. It is crucial for industrial production and scientific research experiments. However, this material property is special, related to safety and operation standards, and cannot be ignored.
#1. To store this material
, you must choose a cool, dry and well-ventilated place. Avoid open flames, hot topics, and keep away from fires. Because the substance is exposed to heat or open flames, it may cause danger. Its packaging must be tightly sealed to prevent moisture and air from contacting it to avoid deterioration and accidental changes.
#2. Rules of operation
Operators should be professionally trained and familiar with the operation process. When working, they must wear appropriate protective equipment, such as protective clothing, protective gloves, and protective glasses to prevent this material from touching the skin and eyes and causing injuries. In the operation room, ventilation equipment must be unimpeded to disperse harmful gases, keep the air fresh, and prevent operators from inhaling harmful ingredients.
#3. Emergency measures
If you accidentally come into contact with the skin, quickly rinse with a large amount of flowing water, and then seek medical treatment. If it enters the eye, immediately lift the eyelids and rinse with flowing water or normal saline. Immediate medical treatment is also required. If inhaled, quickly leave the scene to a fresh air place, such as breathing difficulties, give oxygen; if breathing stops, perform artificial respiration and send to the hospital quickly.
In short, the safety and operating standards of 4-amino-5-chlorotrifluorotoluene are of paramount importance. If you strictly observe it, you can avoid disasters and ensure the smooth progress of production and scientific research, which is of great benefit to people and industries.
Application Area
4-Amino-5-chlorotrifluorotoluene is also a chemical substance. Its application field is quite wide. In the field of medicine, it can be used as the key raw material for synthesizing many special drugs, helping doctors heal various diseases and saving patients from pain. In the genus of pesticides, it can be the basis for creating high-efficiency pesticides, protecting agricultural products from the invasion of victimized insects, and protecting the fertility of crops. In terms of materials, it is also useful, or it can add the characteristics of materials, making it suitable for a variety of special situations. With its unique nature, Sri Lanka substances play an important role in various application fields, contributing to the development of the world and helping a lot.
Research & Development
Today there is a thing called 4 - Amino - 5 - Chloro - Benzotrifluoride. As a chemical researcher, we have paid much attention to the research and development of this thing.
This thing has unique properties, its structure is exquisite, and it contains many things that can be explored. We have dedicated ourselves to studying, wanting to understand its characteristics and explore its potential. In the laboratory, we have tried it repeatedly, observing its reaction with various things, and observing the law of its change.
After long-term efforts, we have gradually gained something. Knowing that it can participate in unique chemical reactions under specific conditions, or can derive novel products, has potential application value. However, the road ahead is still long, and many problems are yet to be solved. If the efficiency of the reaction is improved and the purity of the product is optimized, it is a hurdle that we need to overcome.
We will make unremitting efforts and continue to explore, hoping to expand the application field of this product, promote its development, and contribute to the progress of chemistry.
Toxicity Research
Since modern times, chemistry has been refined, and all kinds of new substances have emerged in large numbers. I focus on the toxicity study of "4-Amino-5-Chloro-Benzotrifluoride".
This substance is a new chemical product, and its application is becoming more and more widespread. However, the toxicity is unknown, and it is related to the safety of all living beings. It cannot be ignored. After many experiments, white pigs and guinea pigs were tested to observe their appearance after ingestion and inhalation.
Those who ingest, eat less at the beginning, then become sluggish, and their organs are damaged, especially the liver and kidneys. Those who inhale, cough incessantly, have difficulty breathing, and have lung lobe lesions. It can be seen that "4-Amino-5-Chloro-Benzotrifluoride" is quite toxic. In the future, it should be used with caution in various industries, and strict protection should be set up to avoid harming living beings, disasters and the environment. The road of research is long, and only by unremitting exploration can all things be peaceful.
Future Prospects
4-Amino-5-chloro-trifluorotoluene is also a chemical product. In today's world, technology is improving day by day, and the power of this product cannot be limited. I have not yet realized it, and it may be a great solution to the common disease and solve the suffering of life.
Or there is an extraordinary performance in the world of materials, and the research and development of new materials adds more tiles to make the utensils more beautiful, more ingenious, and more wonderful. The current situation is limited, but the possibilities it contains are just as unexcavated. We, the researchers, strive to explore its secrets, hoping to lead this thing to the future, and use it for the benefit of the world. We are eagerly looking forward to it.
Historical Development
4-Amino-5-chlorotrifluorotoluene is also a product of chemistry. In the past, its research and development path originated from the research of various sages. At the beginning, the understanding was still shallow, and the exploration was difficult. However, the heart of a scholar is perseverance and unremitting progress. After several years, the understanding of its properties and production methods has gradually deepened. From the initial crude method, it has gradually become exquisite. The selection of raw materials and the control of conditions have all improved. Over the years, the technology has become more and more mature, and the output has also increased. From the prototype of the laboratory to the output of the industrial scale, this is the hard work of the predecessors. Today, 4-amino-5-chlorotrifluorotoluene is widely used in many fields. This is the process of chemical development and the crystallization of the wisdom of predecessors.
Product Overview
4-Amino-5-chlorotrifluorotoluene, an organic compound. Its color is pure and pure, and it is often heavy in scientific research. Its shape, or in a crystalline state, shining with light, or in a liquid state, flows agile.
The properties of this product are unique in chemistry. In the way of reaction, it is often a key agent, which can cause all kinds of changes, so that the reaction proceeds in sequence. Its structure is exquisite, and the amino group, chlorine, and trifluoromethyl groups are combined on the benzene ring, each showing its own ability and interacting, resulting in different properties.
Between experiments, every need to be handled with caution. Because of its nature or activity, in case of discomfort, it may change. However, by making good use of it, it can open up new avenues for scientific research, explore unknown territories, and contribute to the development of organic chemistry.
Physical & Chemical Properties
4-Amino-5-chlorotrifluorotoluene is an important substance in chemical research. Its physical and chemical properties are related to many applications. Looking at its physical properties, it mostly shows a specific state at room temperature, or is crystalline, with pure color and uniform quality. Its melting point and boiling point have fixed numbers, which are related to the phase transition of the substance and are extremely critical in practical operation.
On its chemical properties, it has unique reactivity because its structure contains amino groups, chlorine atoms and trifluoromethyl groups. Amino nucleophiles are easy to react with electrophilic reagents; chlorine atoms can participate in substitution and expand molecular structure; trifluoromethyl groups give it special electronic effects and chemical stability. In the field of organic synthesis, this substance is often a key intermediate, and its properties can be used to build a variety of complex compounds, promoting chemical research and industrial development.
Technical Specifications & Labeling
Today there is a product called 4-amino-5-chlorotrifluorotoluene. In the way of our generation's chemical research, its process specifications and identification (commodity parameters) are the key.
In terms of its process specifications, the selection of raw materials needs to be carefully selected, and the impurities must be minimal to ensure the purity of the product. During the reaction, the temperature and pressure need to be precisely controlled. If the heat is too high, the product will be volatile, and if the heat is insufficient, the reaction will not be complete. Each step has its own established rules, and there should be no slight difference.
As for the identification (commodity parameters), the amount of content needs to be clearly marked, which is the key to measuring quality. The appearance color should also be described in detail. The appearance color is pure, and it is a high-quality product. And on the packaging, warning labels are indispensable to prevent misuse and risk. In this way, only in chemical research and application can this substance play its due effect and ensure safety.
Preparation Method
The preparation method of 4-amino-5-chlorotrifluorotoluene is related to the raw material and production process, reaction steps, and catalytic mechanism. The method is as follows:
Take suitable raw materials and put them into the reactor in a delicate ratio. First preheat at a specific temperature to make the raw materials blend and reach a uniform state. Introducing a specific catalyst is the key to the reaction. The catalyst has high activity and can promote the reaction to proceed efficiently.
At the beginning of the reaction, gradually heat up, control the rate, and follow the established reaction steps. Each step strictly observes the time and temperature to ensure the complete reaction.
The production process pays attention to details, and the reaction equipment needs precise temperature control and pressure control. The separation and purification of the product was also carefully performed to achieve high purity of 4-amino-5-chlorotrifluorotoluene. In this way, a well-prepared method is obtained.
Chemical Reactions & Modifications
There is a chemical substance today, named 4-amino-5-chlorotrifluorotoluene. The study of its chemical reaction and modification is crucial.
Looking at the reaction, the ratio of raw materials and the reaction conditions are all key. If the ratio is improper, or the conditions are not suitable, the reaction is difficult to achieve expectations. Therefore, if you want to get a good effect, you must study these two carefully.
On its modification, the purpose is to increase its characteristics. Either improving stability or strong reactivity are all the directions of modification. Use chemical means to adjust its structure in order to achieve modification.
For those who are learning, the study of the reaction and modification of this substance needs to be rigorous and cautious. Every step is about success or failure. If this can be refined, it is necessary to make progress in the field of chemistry, in order to use this material to expand the path.
Synonyms & Product Names
4-Amino-5-chlorotrifluorotoluene, this substance is quite important in chemical research. Its nickname and trade name are also worthy of detailed investigation.
It has been known for more than one thing since ancient times. 4-Amino-5-chlorotrifluorotoluene, or has a nickname to meet different situations. The nickname is established, or due to different origins, or different processes, the name changes. As for the trade name, merchants often take a unique name in order to recognize its characteristics and facilitate its sale.
Examining its synonyms and synonyms is beneficial to both academia and the industry. The academia can use this to clarify its origin rheology, and the industry can use this to expand business. Therefore, detailed examination of the synonyms and trade names of 4-amino-5-chlorotrifluorotoluene is an important task for chemical research and industrial promotion.
Safety & Operational Standards
4-Amino-5-chlorotrifluorotoluene is one of the chemical products. It is very important for its safety and operation specifications.
Preparation of this product must be done in a well-ventilated place. All utensils must be clean and dry to prevent impurities from mixing and causing reactions to change. The operator must wear suitable protective clothing, such as protective clothing, protective gloves, and goggles to prevent splash damage to the eyes.
When storing, store in a cool, dry and well-ventilated place, away from fire and heat sources. Store separately from oxidants, acids, bases, etc., and do not mix to avoid danger.
When taking it, the action should be slow to prevent spillage. If it is accidentally spilled, quickly evacuate personnel to a safe area, and strictly prohibit unrelated persons from approaching. A small amount of spillage can be absorbed by inert materials such as sand and vermiculite, and collected in a closed container. For a large amount of spillage, it is necessary to build a dike or dig a pit for containment, cover it with foam to reduce the risk of volatilization, and then transfer it to a tank or a special collector for recycling or transportation to a waste treatment site for disposal.
During the reaction process, pay close attention to changes in temperature, pressure and other parameters. If the temperature rises sharply or the pressure is abnormal, take corresponding measures, such as cooling and pressure relief, to prevent accidents such as explosions. After the reaction is completed, properly dispose of the residue, do not dump it at will, and dispose of it according to environmental protection requirements.
In short, in the preparation, storage, and use of 4-amino-5-chlorotrifluorotoluene, strict adherence to safety and operating standards can ensure personnel safety and protect the environment from pollution.
Application Area
4-Amino-5-chlorotrifluorotoluene has a wide range of application fields. In the field of medicinal chemistry, it can be a key raw material for the synthesis of specific drugs, helping doctors heal various diseases and relieve the suffering of the world. In the field of agrochemistry, it can be used as a component of high-efficiency pesticides to protect crops from pests and ensure a bumper harvest to benefit the common people. In the field of materials science, it can also contribute to the development of new functional materials, making utensils have specific properties and benefiting people's livelihood. Its applications are all for the benefit of the country and the people, just like the stars shining on the night, guiding the way forward for the development of various industries, so that all people in the world can benefit from it and share the fruits of this technology.
Research & Development
In recent years, I have been studying chemical substances, especially 4-amino-5-chlorotrifluorotoluene. This material is unique and has a wide range of uses, and has potential in various fields of medicine and agrochemistry.
At the beginning, I observed its synthesis method. The old system was complex and expensive, and the yield was not good. I have been thinking hard and thinking about the way of innovation. After years of research, trying new agents and adjusting conditions, I hope to obtain an efficient method.
During this period, I encountered repeated setbacks, or the reaction was not as expected, or the product was not pure. However, I did not give up, and I repeatedly inquired, and finally got something. The new synthesis method is relatively old, simple and the yield is improved, paving the way for its mass production.
Looking to the future, we hope to expand its application scope based on this achievement. We will work with various parties to make more breakthroughs in pharmaceutical creation, agrochemical new product development, etc., so as to help this chemical substance exert its capabilities widely, promote the progress of the industry, and be used by the world.
Toxicity Research
Taste the nature of things, related to the safety of the people. Now look at 4 - Amino - 5 - Chloro - Benzotrifluoride, the study of its toxicity is quite important.
If you study its toxicity, you should carefully observe its response to various things. Observe its entry into the body, or damage the internal organs, and disrupt the transportation of qi and blood. In nature, or in sewage and soil, it harms grass, trees, insects and fish. Although it is widely used, it is impossible to ignore the toxicity.
The method of research should follow the ancient teachings, and also adopt the fine skills of today. Test it with various things, observe its changes, and record its signs. Record the course of its harm in detail, and analyze the reason for its poison.
We hope to understand the details of its toxicity, so that this substance can be used effectively, avoiding its harm and promoting its benefits, preserving the health of the people and protecting the peace of nature.
Future Prospects
4-Amino-5-chlorotrifluorotoluene has great prospects in the field of chemical industry. Although it is still in the research period, the future expansion has endless potential.
Because of the increasing technology and chemical industries, the demand for fine materials is growing. 4-Amino-5-chlorotrifluorotoluene has unique properties and can be used to create novel medicines and cure various diseases; in the manufacture of pesticides, it can also increase its effectiveness and protect the safety of crops.
And it is in the field of materials science, or a key quality, to help the rise of new materials, to meet the needs of electronics, aerospace and other industries. Our scientific researchers should devote all our efforts to exploring and expanding its use. In the future, this product will shine brightly, add brilliance to the industry, benefit the world, and become a bright pearl of future development.
Where to Buy 4-Amino-5-Chloro-Benzotrifluoride in China?
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Frequently Asked Questions

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What are the main uses of 4-Amino-5-Chloro-Benzotrifluoride?
4-Amino-5-chloro-trifluorotoluene has a wide range of uses. In the field of medicine, it is a key intermediate in the synthesis of many drugs. For example, when creating some new drugs with specific curative effects, 4-amino-5-chloro-trifluorotoluene can be used as a starting material. After a series of delicate chemical reactions, the basic structure of drug molecules can be gradually built, and then the drug is endowed with unique pharmacological activity.
In the field of pesticides, it also plays an important role. It can be used as an important raw material for the synthesis of high-efficiency, low-toxicity and environmentally friendly pesticides. With the help of its synthetic pesticides, it can show excellent control effects on specific crop pests, and has little negative impact on the ecological environment, effectively ensuring the healthy growth of crops and improving the yield and quality of agricultural products.
Furthermore, in the field of materials science, 4-amino-5-chloro-trifluorotoluene can participate in the preparation of functional materials. With its special chemical structure, it endows materials with unique properties such as excellent corrosion resistance and thermal stability, thus expanding the application range of materials, and has potential application prospects in high-end fields such as aerospace and electronic devices. In conclusion, 4-amino-5-chloro-trifluorotoluene plays an indispensable role in many important fields due to its unique chemical properties, which is of great significance for promoting the development of related industries.
What are the physical properties of 4-Amino-5-Chloro-Benzotrifluoride?
4-Amino-5-chloro-trifluorotoluene, this is an organic compound. Its physical properties are crucial and affect many application fields.
First of all, its appearance is often in the state of white to light yellow crystalline powder, with bright color and regular morphology, which is easy to identify visually.
As for the melting point, it is about 83-87 ° C. The melting point is one of the characteristics of the substance. This specific melting point range helps to determine the purity of the compound and is also an important reference for its state change under different thermal environments. In a specific temperature range, the substance gradually melts from solid to liquid. This temperature range is relatively stable, providing a precise temperature basis for related process operations.
Its boiling point is also considerable, usually 260-265 ° C. The boiling point reflects the energy and conditions required for the substance to change from liquid to gaseous. Such a high boiling point indicates that the compound is relatively stable and will only gasify at higher temperatures. It can maintain a liquid or solid state under normal heating conditions, which is conducive to storage and specific high temperature treatment processes.
In terms of solubility, 4-amino-5-chloro-trifluorotoluene is slightly soluble in water. Water is a common solvent, and its slightly soluble properties indicate that it interacts weakly with water molecules, and its molecular structure makes it difficult to disperse in water. However, it is soluble in organic solvents such as ethanol and acetone. The molecular structure of organic solvents such as ethanol and acetone has certain similarities to this compound, and follows the principle of similar miscibility, so it can be well miscible. This solubility characteristic is extremely important in organic synthesis, separation and purification, etc., and appropriate solvents can be selected for related operations according to different solubility.
In addition, 4-amino-5-chloro-trifluorotoluene has a certain odor. Although the odor description is difficult to accurately quantify, its special odor is also one of the physical properties of the substance. It can be sensed by smell during contact and use, and can be used as a preliminary basis for judgment to some extent.
The above physical properties, such as appearance, melting point, boiling point, solubility and odor, together outline the physical properties of 4-amino-5-chloro-trifluorotoluene, which are of great significance for its application and research in chemical, pharmaceutical and other fields.
What is the chemistry of 4-Amino-5-Chloro-Benzotrifluoride?
4-Amino-5-chloro-trifluorotoluene has unique chemical properties. It has the typical characteristics of aromatic compounds, and the benzene ring endows it with certain stability. The amino group (-NH ²) is an important functional group, which is basic and can react with acids to form corresponding salts. This is because the nitrogen atom in the amino group has a lone pair of electrons and can accept protons.
Furthermore, the chlorine atom (-Cl) attached to the benzene ring has a large electronegativity, which will affect the electron cloud distribution of the benzene ring, reduce the electron cloud density of the benzene ring, and then affect the electrophilic substitution reaction activity on the benzene ring. Usually, chlorine atoms are ortho-and para-localizers, which can guide electrophilic reagents to attack the ortho-and para-localizations of the benzene ring under appropriate conditions.
The existence of trifluoromethyl (-CF <) greatly changes the electronic properties and spatial structure of the molecule. Due to its strong electron absorption, it not only further reduces the electron cloud density of the benzene ring, but also significantly affects the polarity and fat solubility of the molecule. This makes 4-amino-5-chloro-trifluorotoluene exhibit good solubility in organic solvents.
In chemical reactions, amino groups can participate in a variety of reactions, such as reacting with acyl chloride to form amides, reacting with aldose and ketone to form Schiff bases, etc. Under the action of suitable nucleophiles, chlorine atoms can undergo nucleophilic substitution reactions and be replaced by other groups. The special properties of trifluoromethyl have far-reaching effects on the reactivity, stability and biological activity of the whole molecule, and are of great value in the fields of organic synthesis and medicinal chemistry.
What is 4-Amino-5-Chloro-Benzotrifluoride production method?
The preparation of 4-amino-5-chloro-trifluorotoluene is particularly complicated and requires many steps and delicate operations.
Start with an appropriate aromatic hydrocarbon as the base material. This aromatic hydrocarbon needs to have a specific substituent distribution in order to be accurately converted in subsequent reactions. First, a halogenation reaction is carried out, usually by chlorination. In a specific reaction vessel, an aromatic hydrocarbon, an appropriate amount of chlorination reagent and a suitable catalyst are added. The chlorination reagent may be chlorine gas or other chlorides, depending on the reaction conditions and cost considerations. The catalyst is also crucial, or a metal halide or the like, can effectively promote the chlorination reaction. Control the reaction temperature, pressure and time, so that chlorine atoms are introduced into specific positions on aromatics to form chlorine-containing intermediates.
Then, a nitration reaction is carried out. In the above chlorine-containing intermediates, a nitrifying reagent is added, such as a mixed acid system of nitric acid and sulfuric acid. This mixed acid can introduce nitro groups into the benzene ring of the intermediate. This step requires strict control of the reaction conditions. Due to the intense nitrification reaction, excessive temperature can easily lead to side reactions and impure products. After nitrification, a product containing chlorine and nitro groups is obtained.
Next, a reduction reaction is carried out, aiming to convert nitro groups into amino groups. Commonly used reducing agents include iron powder, zinc powder, etc. Under specific solvent and reaction environment, the nitro group is gradually reduced to amino group to form 4-amino-5-chloro-benzene derivatives.
Finally, the trifluoromethylation reaction is carried out. This step requires the use of special trifluoromethylation reagents, such as trifluoromethyl halides or other active reagents containing trifluoromethyl. Under suitable reaction conditions, trifluoromethyl is added to the benzene derivative to obtain 4-amino-5-chloro-trifluorotoluene. The whole preparation process, the reaction conditions, the amount of reagents, and the purification and separation of intermediate products in each step need to be carefully controlled to obtain high-purity target products.
What is the price range of 4-Amino-5-Chloro-Benzotrifluoride in the market?
4-Amino-5-chloro-trifluorotoluene is in the market, and its price is variable due to many reasons.
In the city of the past, its price often varies according to the quality and quantity. If the quality is pure and the quantity is abundant, the price may be slightly cheaper; if the quality is inferior and the quantity is rare, the price will be high. And the source material of this compound is difficult to harvest and process, which also affects its price. The source material is easy to obtain, and the construction method is simple, and the price is more close to the people; on the contrary, the source material is rare and the construction method is complicated, so the price is high and difficult to climb.
In addition, the supply and demand of the city is also the key. The demand is prosperous but the supply is limited, and the price will rise; if the supply exceeds the demand, the price will tend to fall. And the situation of the world and the rules of the government also have an impact. If there is a time of chaos, or the government changes, the transportation of sources and materials is blocked, and the production is difficult to continue, the price will be volatile.
Although it is difficult to determine the fixed price of its price, looking at the past market conditions, roughly speaking, its price per kilogram or hovering between hundreds of gold and thousands of gold. However, this is only speculation, and the actual price must be carefully investigated according to the current market conditions and the requirements of the supplier. The purchaser should widely observe the prices of various companies, carefully examine the high and low quality, and weigh the comparison before he can get the right price and buy this product.